Monday, June 15, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11078298

    Antibodies to ubiquitin C-terminal hydrolase L1 (UCH-L1) and glial fibrillary acidic protein (GFAP) and related methods

    BANYAN BIOMARKERS, INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11078264

    Inhibiting granulocyte macrophage-colony stimulating factor (GM-CSF) prevents preterm birth

    UNIVERSITY OF CONNECTICUT · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11078257

    Recombinant gram negative bacteria and methods of generating and utilizing same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11078486

    Compounds and methods for reducing ATXN2 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11078250

    High-activity long-acting hypoglycemic fusion protein as well as preparation method and medical application thereof

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11078256

    Methods and compositions for inhibiting cancer cell growth

    The Board of Regents of the University of Texas System · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11077123

    Use of bile acids and bile salts as anti bacterial agents for inhibition of bacterial conjugation and horizontal gene transfer

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11078227

    5′-cyclo-phosphonate modified nucleotides

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11078205

    Selective inhibitors of protein arginine methlytransferase 5 (PRMT5)

    Prelude Therapeutics, Incorporated · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11078239

    Prefusion PIV F immunogens and their use

    The United States of America as Represented by the Secretary, Dept. of Health and Human Services · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11078245

    Colon and pancreas cancer peptidomimetics

    PRECISION BIOLOGICS, INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11077057

    Polymer-grafted nanobins

    Northwestern University · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11076599

    Antimicrobial coating comprising chalcogenide nano-particles capped by chitosan

    The Board of Regents of the University of Texas System · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11077068

    Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions

    Aquestive Therapeutics, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11077090

    Compounds and compositions and uses thereof

    PGI Drug Discovery LLC · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11077101

    Compounds and methods of use

    Tango Therapeutics, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11078170

    Cyclic sulfamide compounds and methods of using same

    ASSEMBLY BIOSCIENCES, INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11077072

    Binge behavior regulators

    CLEARMIND MEDICINE INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11077078

    Compositions and methods for the treatment of cancer

    KoDiscovery, LLC · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11077079

    GHB formulation and method for its manufacture

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11077108

    Allosteric corticotropin-releasing factor receptor 1 (CRFR1) antagonists that decrease p-tau and improve cognition

    The Regents of the University of California · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11077117

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11077114

    Stabilized formulations of CNS compounds

    Supernus Pharmaceuticals, Inc. · Granted Tue Aug 03 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 29 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. WO 2021152186

    ANTICORPS CCR8 POUR APPLICATIONS THÉRAPEUTIQUES

    BAYER AG [DE] · Granted Thu Aug 05 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 31 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11083736

    Compositions comprising triterpenoids

    REGENERA PHARMA LTD. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11083850

    Secure smart dosing system with automated delivery, measurement, and management

    Vivera Pharmaceuticals Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11084809

    N-((HET)arylmethyl)-heteroaryl-carboxamides compounds as kallikrein inhibitors

    KalVista Pharmaceuticals Limited · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11083794

    Methods and compositions for self-regulated release of active pharmaceutical ingredient

    Acurx Pharmaceuticals, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11083788

    Nanoemulsion compositions for preventing, suppressing or eliminating allergic and inflammatory disease

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11083797

    Long-acting polymeric delivery systems

    Heron Therapeutics, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11083753

    Targeted replacement of endogenous T cell receptors

    The Regents of the University of California · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11083730

    Long-acting polymeric delivery systems

    Heron Therapeutics, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11084844

    Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom

    Ionis Pharmaceuticals, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11084856

    Interleukin-4 receptor-binding fusion proteins and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11084859

    Targeted mutant interferon-gamma and uses thereof

    Orionis Biosciences, Inc · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11084795

    CFTR regulators and methods of use thereof

    The Regents of the University of California · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11084872

    Method for treating breast cancer

    ADC THERAPEUTICS SA · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11083745

    Antisense oligomers for treatment of autosomal dominant mental retardation-5 and Dravet Syndrome

    STOKE THERAPEUTICS, INC. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11083737

    Methods of administering deflazacort therapy

    PTC THERAPEUTICS, INC. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11083708

    Pharmacological restoration of epithelial or endothelial barrier integrity by agents blocking EPAC/RAP1 signaling

    The Regents of the University of California · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11083720

    Indazole inhibitors of fructokinase (KHK) and methods of use in treating KHK-mediated disorders or diseases

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11083752

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11083758

    Placental membrane preparations and methods of making and using same for regenerating cartilage and spinal intervertebral discs

    Prime Merger Sub, LLC · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11083799

    Materials and methods for treatment of hereditary haemochromatosis

    CRISPR THERAPEUTICS AG · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11083801

    Factor VIII mutation repair and tolerance induction

    The United States Government Represented by the Departrment of Veteran Affairs · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11084798

    2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors

    IDEAYA Biosciences, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11084842

    Glucopyranosyl derivative and use thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11084850

    Recombinant prefusion RSV F proteins and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.