Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11084850

    Recombinant prefusion RSV F proteins and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11084865

    VEGF antagonist formulations suitable for intravitreal administration

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11083696

    Dispersion anaesthetic device

    University College Cardiff Consultants Limited · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11083801

    Factor VIII mutation repair and tolerance induction

    The United States Government Represented by the Departrment of Veteran Affairs · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11083635

    Tampon delivery system for a pharmaceutical, holistic or medicinal component

    Herphoric, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11084798

    2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors

    IDEAYA Biosciences, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11084842

    Glucopyranosyl derivative and use thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11083708

    Pharmacological restoration of epithelial or endothelial barrier integrity by agents blocking EPAC/RAP1 signaling

    The Regents of the University of California · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11083720

    Indazole inhibitors of fructokinase (KHK) and methods of use in treating KHK-mediated disorders or diseases

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11083736

    Compositions comprising triterpenoids

    REGENERA PHARMA LTD. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11083752

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Aug 10 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 05 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11091525

    Method of refolding an interleukin-2 (IL-2) protein

    Nektar Therapeutics · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11091467

    Modulators of THR-β and methods of use thereof

    Aligos Therapeutics, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11090224

    Adaptor for a dispensing container in a planetary mixer

    MEDISCA PHARMACEUTIQUE INC. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11090286

    Methods of treating and preventing breast cancer with S-equol

    The Board of Regents of the University of Texas System · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11090290

    Clonidine and/or clonidine derivatives for use in the prevention of skin injury resulting from radiotherapy

    Monopar Therapeutics Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11090272

    Lurasidone solid dispersion and preparation method thereof

    SUNSHINE LAKE PHARMA CO., LTD. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11090325

    Compositions for treating ebola virus infection

    RedHill Biopharma Ltd. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11090326

    Fixed-dose pharmaceutical composition comprising rifabutin, clarithromycin, and clofazimine

    RedHill Biopharma Ltd. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11090310

    Methods and compositions for treating hypertriglyceridemia

    The Regents of the University of California · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11090313

    Methods for inhibiting muscle atrophy

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11090349

    Plant extract obtained from Morus plant leaves, compositions containing same, method of extraction and uses thereof

    Botanic Century (Beijing) Co. Ltd. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11090361

    Activin receptor type IIa variants and methods of use thereof

    Keros Therapeutics, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11090396

    Compounds and methods for the detection of TRPV-6 cancers and drug delivery

    Soricimed Biopharma Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11091441

    Solid state crystalline forms of a selective potassium channel modulator

    Xenon Pharmaceuticals Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11091473

    Compounds for pain treatment, compositions comprising same, and methods of using same

    ACADIA Pharmaceuticals Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11091464

    Pyridazinone compounds and uses thereof

    EDGEWISE THERAPEUTICS, INC. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11091795

    Compositions and methods for diagnosing and treating arrhythmias

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11091761

    Organic compositions to treat HSF1-related diseases

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11091561

    HER-2 binding antibodies

    MAB Discovery GmbH · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11091555

    Method of treating gastric cancer with anti-FGFR2-IIIb antibodies and modified FOLFOX6 chemotherapy

    Five Prime Therapeutics, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11091532

    T cell which co-expresses a CD19 chimeric antigen receptor and a CD22 chimeric antigen receptor

    AUTOLUS LIMITED · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11091534

    Factor VIII complex with XTEN and von Willebrand Factor protein, and uses thereof

    BIOVERATIV THERAPEUTICS INC. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11091529

    Peptides having reduced toxicity that stimulate cholesterol efflux

    The Regents of the University of California · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11091519

    Purification of virus like particles

    Takeda Vaccines, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11091518

    Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same

    Inovio Pharmaceuticals, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11091516

    Synthetic binder of breast cancer stem cells

    The Board of Regents of the University of Texas System · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11091509

    HPPK inhibitors useful as antibacterial agents

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11091501

    Heterocyclic compounds as RSV inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11091495

    Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors

    Mirati Therapeutics, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11090293

    Use of gaboxadol for the treatment of Tourette syndrome, tics and stuttering

    OVID THERAPEUTICS INC. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11090269

    Controlled release dosage forms for high dose, water soluble and hygroscopic drug substances

    Jazz Pharmaceuticals, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11090285

    Treatment of circadian rhythm disorders

    VANDA PHARMACEUTICALS INC. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11090332

    Antigen specific mRNA cellular cancer vaccines

    Regen Biopharma, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11090344

    Adenovirus and immunomodulator combination therapy

    The Board of Regents of the University of Texas System · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11091472

    PI-kinase inhibitors with anti-infective activity

    The Regents of the University of California · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11090311

    Methods and compositions comprising ursolic acid and/or resveratrol for treating diabetes, or cancer

    The Board of Regents of the University of Texas System · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11090308

    Methods of treating liver disorders or lipid disorders with a THR-beta agonist

    Madrigal Pharmaceuticals, Inc. · Granted Tue Aug 17 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 12 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.