Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. CA 3144557

    LIGANDS D'ANTIGENE MEMBRANAIRE SPECIFIQUE DE LA PROSTATE (PSMA) ET LEURS UTILISATIONS

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Jan 07 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 02 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. WO 2021001362

    LIGANDS D'ANTIGÈNE MEMBRANAIRE SPÉCIFIQUE DE LA PROSTATE (PSMA) ET LEURS UTILISATIONS

    ADVANCED ACCELERATOR APPLICATIONS ITALY SRL [IT] · Granted Thu Jan 07 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 02 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10889637

    Methods of treating an osteolytic tumor and spinal cord injury by administering connexin (Cx) 43 hemichannel-binding antibodies

    The Board of Regents of the University of Texas System · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10888565

    Compounds and compositions for ossification and methods related thereto

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10888617

    Cured oil-hydrogel biomaterial compositions for controlled drug delivery

    ATRIUM MEDICAL CORPORATION · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10889556

    Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease

    The Regents of the University of California · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10889834

    Methods and compositions for enhancing targeted transgene integration

    Sangamo Therapeutics, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10888578

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10888597

    Composition for treating brain stroke

    ENLIVEN BIOTECHNOLOGY CO, LTD. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10889576

    Phthalazinone compounds and methods for the treatment of cystic fibrosis

    Flatley Discovery Lab, LLC · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10888618

    Method of treating cancer

    Intensity Therapeutics, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10888619

    Stable aqueous etanercept composition

    Coherus BioSciences, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10889543

    Fine-tune modulators of neuronal excitability for neuropsychiatric disorders

    The Board of Regents of the University of Texas System · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10889813

    Programmed cell death 1 ligand 1 (PD-L1) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10888529

    Vehicles for the transfection of miRNAs

    UNIVERSIDAD DEL PAÍS VASCO / EUSKAL HERRIKO UNIBERTSITATEA · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10888558

    Regimens of tafenoquine for prevention of malaria in malaria-naive subjects

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10888601

    Use of a VEGF antagonist to treat angiogenic eye disorders

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10889592

    Thienopyrazine carboxamides as ubiquitin-specific protease inhibitors

    Valo Early Discovery, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10889577

    Solid forms of an sGC stimulator

    Cyclerion Therapeutics, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10889580

    Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof

    VTV THERAPEUTICS LLC · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10889587

    Tebipenem pivoxil crystalline forms, compositions including the same, methods of manufacture, and methods of use

    SPERO THERAPEUTICS, INC. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10889607

    Sialic acid analogs

    Ultragenyx Pharmaceutical Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10889817

    Oligonucleotide therapy for Leber Congenital Amaurosis

    ProQR Therapeutics II B.V. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10889538

    Medium chain fatty acid esters of beta-hydroxybutyrate and butanediol and compositions and methods for using same

    The Regents of the University of California · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10888517

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10889562

    Prodrugs of Nrf2 activating compounds and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10888499

    Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom

    Aquestive Therapeutics, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10888581

    Chimeric antigen receptor and methods of use thereof

    The Regents of the University of California · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10889625

    Peptide-based methods for treating neurological injury

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10888516

    Soluble estradiol capsule for vaginal insertion

    Compass Therapeutics LLC · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10888609

    CD200 inhibitors and methods of use thereof

    Regents of the University of Minnesota · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10888589

    Modulation of stem cells using zinc finger proteins

    Sangamo Therapeutics, Inc. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10889561

    Process of making somatostatin modulators

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10888554

    Salts of heterocyclic modulators of HIF activity for treatment of disease

    The Board of Regents of the University of Texas System · Granted Tue Jan 12 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 07 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. WO 2021005497

    ANTAGONISTES DU CGRP ET DÉRIVÉS DE CLOSTRIDIUM POUR LE TRAITEMENT DE TROUBLES ASSOCIÉS À LA DÉPRESSION CORTICALE ENVAHISSANTE

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Jan 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. WO 2021005493

    ANTAGONISTES DU CGRP ET TOXINES BOTULINIQUES POUR LE TRAITEMENT DE TROUBLES INFLAMMATOIRES ET NEUROLOGIQUES

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Jan 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. WO 2021005494

    ANTAGONISTES DU CGRP ET DÉRIVÉS DE CLOSTRIDIALES POUR LE TRAITEMENT DE TROUBLES NEUROPSYCHIATRIQUES ET NEUROLOGIQUES

    ALLERGAN PHARMACEUTICALS INT LTD [IE] · Granted Thu Jan 14 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jan 09 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10894061

    Therapeutic methods involving modulating inflammasome activation of myeloid-derived suppressor cells

    Regents of the University of Minnesota · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10894007

    Hair care composition with encapsulated moisturizers and method to deliver extended moisture release to the hair

    Henkel (China) Investment Co., Ltd. · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10894077

    Synthetic methylmalonyl-CoA mutase transgene for the treatment of MUT class methylmalonic acidemia (MMA)

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10894053

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10894044

    Combination of topoisomerase-I inhibitors with immunotherapy in the treatment of cancer

    The Board of Regents of the University of Texas System · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10894786

    Substituted pyrazole derivatives as selective CDK12/13 inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10894816

    Use of IL-15 to increase thymic output and to treat lymphopenia

    The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10894033

    Multicyclic compounds and methods of use thereof

    PGI Drug Discovery LLC · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10894034

    Anti-neoplastic compounds and methods targeting QSOX1

    ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10894087

    Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds

    Nektar Therapeutics · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10894050

    Methods of synthesizing thyroid hormone analogs and polymorphs thereof

    Madrigal Pharmaceuticals, Inc. · Granted Tue Jan 19 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jan 14 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.