Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10654898

    Recombinant human/bovine parainfluenza virus 3 (B/HPIV3) expressing a chimeric RSV/BPIV3 F protein and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10654864

    Modified cytotoxins and their therapeutic use

    The Regents of the University of California · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10654802

    Indoline derivatives and method for using and producing the same

    Arizona Board of Regents on Behalf of the University · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10653789

    Polymer-drug conjugates for combination anticancer therapy

    The Regents of the University of California · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10653723

    Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10653710

    Combination therapy for treating malignancies

    Agios Pharmaceuticals, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10653689

    Combination-based treatment method

    Nektar Therapeutics · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10653665

    Method of treatment

    VANDA PHARMACEUTICALS INC. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10653172

    Natural stilbenes as sweeteners or sweetener enhancer

    Analyticon Discovery GmbH · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10653652

    Use of (1S,3S)-3-amino-4-(difluoromethylidene) cyclopentane-1-carboxylic acid and (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid in the treatment of tinnitus, acute sensorineural hearing loss, meniere'S disease, tourette'S syndrome, attention deficit hyperactivity disorder and addiction

    OVID THERAPEUTICS INC. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10653725

    Methods for improving health of farmed fish

    AKER BIOMARINE ANTARCTIC AS · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10653727

    Use of gram negative species to treat atopic dermatitis

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10653800

    Oligonucleotide-based probes for detection of bacterial nucleases

    INTEGRATED DNA TECHNOLOGIES, INC. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10654916

    Compositions and methods for the treatment of neuromyelitis optica

    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10653169

    Food thickening agent, method for producing food thickening agent

    Kent Precision Foods Group, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10653173

    Method for masking unpleasant taste

    Analyticon Discovery GmbH · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 2020155578

    Pharmaceutical Formulations for Subcutaneous Administration

    ABBVIE INC [US] · Granted Thu May 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10662295

    Trehalose hydrogels for stabilization and delivery of proteins

    The Regents of the University of California · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10660856

    Porous silica gel as a carrier for liquid technologies

    W.R. Grace & Co.-Conn. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10660850

    Compositions and methods of making brittle-matrix particles through blister pack freezing

    The Board of Regents of the University of Texas System · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10660895

    Methods for treating amyotrophic lateral sclerosis

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10662146

    Prodrugs of fencamfamine

    Praxis Bioresearch, LLC · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10660947

    Vaccine composition

    TURNSTONE LIMITED PARTNERSHIP · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10661095

    Photodynamic therapy for use in treating cancer

    The Board of Regents of the University of Texas System · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10660968

    Spirocyclic degronimers for target protein degradation

    C4 THERAPEUTICS, INC. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10662183

    Inhibitors of myocardin-related transcription factor and serum response factor (MRTF/SRF)-mediated gene transcription and methods for use of the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10660901

    Pyrrolobenzodiazepines and conjugates thereof

    Mersana Therapeutics, Inc. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10660904

    Optimizing mifepristone levels for cushing's patients

    Corcept Therapeutics Incorporated · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10662184

    Benzenesulfonamide compounds and their use as therapeutic agents

    Xenon Pharmaceuticals Inc. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10662192

    Modulators of ATP-binding cassette transporters

    Vertex Pharmaceuticals Incorporated · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10662161

    Pyrimidines and uses thereof

    Regents of the University of Minnesota · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10662440

    Self-limiting viral vectors encoding nucleases

    Precision BioSciences, Inc. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10662425

    Materials and methods for treatment of autosomal dominant retinitis pigmentosa

    CRISPR THERAPEUTICS AG · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10662244

    Methods for tumor treatment using CD3XCD20 bispecific antibody

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10662416

    Engineered meganucleases specific for recognition sequences in the hepatitis B virus genome

    Precision BioSciences, Inc. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10662430

    RNA interference in ocular indications

    Phio Pharmaceuticals Corp. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10663473

    Method of identifying a status of a mucosal intestinal epithelial barrier to improve treatment of inflammatory bowel disease

    Maximus Diagnostic Technologies LLC · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10662238

    Single domain VHH antibodies directed to norovirus GI.1 and GII.4 and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10660918

    Method for enhancing insulin like growth factor 1 receptor expression of mesenchymal stem cell, method for isolating mesenchymal stem cell, and use of mesenchymal stem cell

    China Medical University · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10660889

    Compounds for treatment of cancer

    Curegenix, Inc. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10662160

    Crystalline salts of a plasma kallikrein inhibitor

    BioCryst Pharmaceuticals, Inc. · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10662215

    Cyclic peroxides as prodrugs for selective delivery of agents

    The Regents of the University of California · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10660923

    Sinusitis diagnostics and treatments

    The Regents of the University of California · Granted Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 21 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10669347

    Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use

    Sutro Biopharma, Inc. · Granted Tue Jun 02 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10669298

    Mannose derivatives for treating bacterial infections

    Vertex Pharmaceuticals Incorporated · Granted Tue Jun 02 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10668129

    Synergistic combination of neuronal viability factors and uses thereof

    The Regents of the University of California · Granted Tue Jun 02 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10668107

    Methods of transdifferentiation and methods of use thereof

    TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD. · Granted Tue Jun 02 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10668049

    Methods of treating cognitive decline with transforming growth factor beta inhibitors

    The Regents of the University of California · Granted Tue Jun 02 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 28 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.