Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10633363

    EPAC1 activators as HIV latency reversal agents (LRA)

    The Board of Regents of the University of Texas System · Granted Tue Apr 28 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 23 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 2020131224

    Methods for Synthesis of Radionuclide Complex

    ADVANCED ACCELERATOR APPLICATIONS ITALY S R L [IT] · Granted Thu Apr 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. DE 202020000818

    Mittel zur äußeren Pflege der Haut von Tieren, insbesondere von Pferden

    CP PHARMA HANDELSGESELLSCHAFT MBH [DE] · Granted Mon May 04 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Sun Apr 29 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10640487

    Solid state forms of Nilotinib salts

    Teva Pharmaceuticals USA, Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10639278

    Delivery of agents using metastable liposomes

    LIPELLA PHARMACEUTICALS, INC. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10639277

    Multi-functional echogenic immunoliposomes for directed stem cell delivery to atheroma

    The Board of Regents of the University of Texas System · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10639289

    Application of neuraminidase and inhibitors thereof in myocardial ischemia and myocardial infarction

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10639302

    Use of CDK9 inhibitors to reduce cartilage degradation

    The Regents of the University of California · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10639272

    Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10639375

    Progesterone formulations

    Compass Therapeutics LLC · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10639320

    Pharmaceutical composition comprising gold-containing agent for preventing or treating liver fibrosis or liver cirrhosis

    KOREA UNITED PHARM. INC. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10639383

    Methods and compositions for engineering immunity

    Sangamo Therapeutics, Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10639308

    sGC stimulators

    Cyclerion Therapeutics, Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10639357

    Enzymes and methods for cleaving N-glycans from glycoproteins

    The Regents of the University of California · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10640771

    Compositions and methods for treating and preventing macular degeneration

    THE UNITED STATES OF AMERICA AS REPRESENTED BY THE · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10640571

    Human monoclonal antibodies specific for glypican-3 and use thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10640485

    Methods and compounds for restoring mutant p53 function

    PMV PHARMACEUTICALS, INC. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10639360

    Methods for treating hypophosphatemic disorders

    Ultragenyx Pharmaceutical Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10639348

    Peptides with anti-cancer activity

    IDP DISCOVERY PHARMA, S.L. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10640770

    Hepatitis D virus (HDV) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10640534

    Therapeutically active compositions and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10640511

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10639350

    Methods and pharmaceutical compositions for improving wound healing using CD24

    The Medical Research, Infrastructure and Health Services Fund of the Tel-Aviv Medical Center · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10640535

    Identification of MHC class I phospho-peptide antigens from breast cancer utilizing SHLA technology and complementary enrichment strategies

    The Board of Regents of the University of Oklahoma · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10640558

    Anti-IL-25 antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10640570

    Chimeric antigen receptors, compositions, and methods

    Regents of the University of Minnesota · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10640566

    Nucleic acid molecules encoding antibodies to the human glucagon receptor

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10640791

    Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

    The Regents of the University of California · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10640517

    Bicyclic heterocyclyl derivatives as IRAK4 inhibitors

    Aurigene Discovery Technologies Limited · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10640501

    Methods of preparing inhibitors of influenza viruses replication

    Vertex Pharmaceuticals Incorporated · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10640493

    Phthalazine derivatives as inhibitors of PARP1, PARP2, and/or tubulin useful for the treatment of cancer

    The Regents of the University of California · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10639330

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10639303

    Alkaloids and their preparation and application as anti-HSV-1 agents

    OCEAN UNIVERSITY OF CHINA · Granted Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 30 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. AR 113437

    INHIBIDORES MITOCONDRIALES PARA EL TRATAMIENTO DE TRASTORNOS DE PROLIFERACIÓN

    BASILEA PHARM INT AG [CH] · Granted Wed May 06 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue May 01 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. CA 3118090

    COMPOSITIONS ET PROCEDES POUR EDITION DU GENOME A MEDIATION PAR NHEJ

    CRISPR THERAPEUTICS AG [CH] · Granted Thu May 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10646443

    Sustained release olanzapine formulations

    TEVA PHARMACEUTICALS INTERNATIONAL GMBH · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10647697

    Nrf2 activating compounds and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10646480

    Formulations of pimavanserin

    ACADIA Pharmaceuticals Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10646481

    Pharmaceutical composition and administrations thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10646435

    Pasty bio-adhesive sustained release compositions

    CARE & PHARMA PERSPECTIVES SA · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10646474

    Glucocorticoid receptor modulators to treat pancreatic cancer

    Corcept Therapeutics Incorporated · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10647710

    Thiazole derivative and applications thereof

    Medshine Discovery Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10647711

    Azepin-2-one derivatives as RSV inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10646577

    mTORC1 inhibitors

    The Regents of the University of California · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10646537

    Traditional Chinese medicine for treating abdominal obesity

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10646475

    SHMT inhibitors

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10646438

    Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine

    The Board of Regents of the University of Texas System · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10646485

    Process of making stable abuse-deterrent oral formulations

    Collegium Pharmaceutical, Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.