Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10647689

    Apelin receptor agonists and methods of use thereof

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10646593

    Activatable membrane-interacting peptides and methods of use

    The Regents of the University of California · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10647785

    High concentration chitosan-nucleic acid polyplex compositions

    ENGENE, INC. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10646588

    RP2 and RPGR vectors for treating X-linked retinitis pigmentosa

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10646578

    Polymer derivatives having particular atom arrangements

    Nektar Therapeutics · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10646557

    Vaccine composition

    TURNSTONE LIMITED PARTNERSHIP · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10646574

    Formulations of intraarticular pharmaceutical agents and methods for preparing and using the same

    The Board of Regents of the University of Texas System · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10646575

    Heterocyclic degronimers for target protein degradation

    C4 THERAPEUTICS, INC. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10646591

    Imaging agents for imaging protease activity and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10647661

    Carboxamides as modulators of sodium channels

    Vertex Pharmaceuticals Incorporated · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10647720

    Pyrimido-pyridazinone compounds and methods of use thereof

    Asana BioSciences, LLC · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10648001

    Method of treating mucopolysaccharidosis type I or II

    Sangamo Therapeutics, Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10647964

    Non-neuroinvasive viruses and uses thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10647754

    Stabilized single human CD4 domains and fusion proteins

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10649053

    Cardiac late gadolinium enhancement MRI for patients with implanted cardiac devices

    The Regents of the University of California · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10646481

    Pharmaceutical composition and administrations thereof

    Vertex Pharmaceuticals Incorporated · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10647711

    Azepin-2-one derivatives as RSV inhibitors

    Enanta Pharmaceuticals, Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10646577

    mTORC1 inhibitors

    The Regents of the University of California · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10646523

    Combination comprising spirulina and palmitoylethanolamide and/or salts or pharmaceutically acceptable derivatives thereof and their formulations, for use in the prevention and/or in the treatment of hyperactivated tissue conditions

    AGAIN LIFE ITALIA SRL · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10646537

    Traditional Chinese medicine for treating abdominal obesity

    INFINITUS (CHINA) COMPANY LTD. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10646475

    SHMT inhibitors

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10646438

    Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine

    The Board of Regents of the University of Texas System · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10646517

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10647697

    Nrf2 activating compounds and uses thereof

    Rigel Pharmaceuticals, Inc. · Granted Tue May 12 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 07 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. WO 2020095183

    COMBINAISON POUR LE TRAITEMENT DU CANCER

    PFIZER [US] · Granted Thu May 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. WO 2020094634

    PROMÉDICAMENTS DE THIOPHÈNE DE NALTROXÈNE POUR COMPOSITIONS INJECTABLES À ACTION PROLONGÉE ET PROCÉDÉS ASSOCIÉS

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu May 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed May 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10653727

    Use of gram negative species to treat atopic dermatitis

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10653150

    Shelf life and color profile of resin compositions with silver nanoparticles

    The Board of Regents of the University of Texas System · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10653704

    Inhalable formulation

    Teva Branded Pharmaceutical Products R&D, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10653721

    Peroxide formulations and methods and applicators for using the same

    Aclaris Therapeutics, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10653169

    Food thickening agent, method for producing food thickening agent

    Kent Precision Foods Group, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10655183

    Carcinoma diagnosis and treatment based on ODC1 genotype

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10653173

    Method for masking unpleasant taste

    Analyticon Discovery GmbH · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10655109

    Recombinant respiratory syncytial virus stains with mutations in the M2-2 ORF providing a range of attenuation phenotypes

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10654898

    Recombinant human/bovine parainfluenza virus 3 (B/HPIV3) expressing a chimeric RSV/BPIV3 F protein and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10654864

    Modified cytotoxins and their therapeutic use

    The Regents of the University of California · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10654802

    Indoline derivatives and method for using and producing the same

    Arizona Board of Regents on Behalf of the University · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10654850

    Pyridazinones and methods of use thereof

    Goldfinch Bio, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10653725

    Methods for improving health of farmed fish

    AKER BIOMARINE ANTARCTIC AS · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10653749

    Targeting GIV-GEF-GI signaling for treating diverse diseases

    The Regents of the University of California · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10653789

    Polymer-drug conjugates for combination anticancer therapy

    The Regents of the University of California · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10653723

    Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10653710

    Combination therapy for treating malignancies

    Agios Pharmaceuticals, Inc. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10653689

    Combination-based treatment method

    Nektar Therapeutics · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10653665

    Method of treatment

    VANDA PHARMACEUTICALS INC. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10653172

    Natural stilbenes as sweeteners or sweetener enhancer

    Analyticon Discovery GmbH · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10653652

    Use of (1S,3S)-3-amino-4-(difluoromethylidene) cyclopentane-1-carboxylic acid and (S)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid in the treatment of tinnitus, acute sensorineural hearing loss, meniere'S disease, tourette'S syndrome, attention deficit hyperactivity disorder and addiction

    OVID THERAPEUTICS INC. · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10653743

    Methods for the treatment of depression and anxiety by a melanocortin 5 receptor antagonist, PG-20N

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 14 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.