Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. MLN1202 Placebo

    Takeda

    Diabetic Nephropathy

    phase 2 small molecule terminated

    1 trial
  2. MLS-101 (Part I)

    Mineralys Therapeutics

    Hypertension, Renal

    phase 2 small molecule completed

    1 trial
  3. MLS-101-206

    Mineralys Therapeutics

    Chronic Kidney Disease

    phase 2 small molecule completed

    1 trial
  4. MMV390048 40mg

    CNS Pharmaceuticals

    Malaria

    phase 2 small molecule completed

    1 trial
  5. MN-166 (50 mg) First

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Abuse

    phase 2 small molecule completed

    1 trial
  6. MOGAMULIZUMAB

    Ningbo Cancer Hospital

    Cutaneous T-cell lymphoma, a category of cancers of lymphocytes (a type of white blood cells) that primarily involve the skin, Cutaneous T-cell lymphoma (Mycosis Fungoides (MF)) and Sézary Syndrome (SS))

    phase 2 small molecule active

    1 trial
  7. MOL4239

    Moleculin Biotech

    Psoriasis

    phase 2 small molecule completed

    1 trial
  8. MOR 106

    Lakefront Biotherapeutics NV

    Atopic Dermatitis

    phase 2 small molecule terminated

    1 trial
  9. MOR106

    Lakefront Biotherapeutics NV

    Atopic Dermatitis

    phase 2 small molecule terminated

    1 trial
  10. MOR208C115

    Incyte

    Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

    phase 2 small molecule active

    1 trial
  11. MORAb-202-G000-201

    Eisai Co.,

    Solid tumors in 4 tumor types: platinum resistant ovarian cancer, triple-negative breast cancer (TNBC), endometrial cancer (EC), and non-small cell lung cancer adenocarcinoma; NSCLC).

    phase 2 small molecule active

    1 trial
  12. MP-424 (Telaprevir)

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 2 small molecule completed

    1 trial
  13. MPH966

    Mereo BioPharma Group plc

    Hematologic Malignancy

    phase 2 small molecule terminated

    1 trial
  14. MR-130A-01

    Mylan Pharma UK

    Investigation of maintenance of ovulation inhibition after intentional application errors for indication of contraception in healthy subjects

    phase 2 small molecule active

    1 trial
  15. MRG003

    Shanghai University of Traditional Chinese Medicine

    Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck

    phase 2 small molecule active

    1 trial
  16. MRG003 combined with Dalpicicilip

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head and Neck Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  17. MRG003 combined with Pucotenlimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head and Neck Squamous Cell Carcinoma (HNSCC)

    phase 2 small molecule active

    1 trial
  18. MRTX1719

    Bristol-Myers Squibb Australia Pty Ltd

    Advanced or Metastatic Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  19. MRX-6

    Akari Therapeutics Plc

    Atopic Dermatitis

    phase 2 small molecule terminated

    1 trial
  20. MRx-4DP0004

    4D Molecular Therapeutics

    COVID-19

    phase 2 small molecule terminated

    1 trial
  21. MRx0518

    4D Molecular Therapeutics

    Urothelial Carcinoma

    phase 2 small molecule terminated

    1 trial
  22. MRx0518

    4D Molecular Therapeutics

    Oncology

    phase 2 small molecule terminated

    1 trial
  23. MS200095-0031

    Merck Sharp and Dohme

    Lung Cancer

    phase 2 small molecule active

    1 trial
  24. MS200569_0003

    Merck Sharp and Dohme

    Systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE)

    phase 2 small molecule active

    1 trial
  25. MS201924_0002

    Merck Sharp and Dohme

    Epithelial ovarian cancer that progressed on prior PARP inhibitor therapy

    phase 2 small molecule active

    1 trial
  26. MS201924_0022

    Merck Sharp and Dohme

    Non-Squamous Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  27. MSC

    Shandong University

    Type 2 Diabetes

    phase 2 mab active

    1 trial
  28. MSC

    The Children's Hospital of Zhejiang University School of Medicine

    BPD - Bronchopulmonary Dysplasia

    phase 2 small molecule active

    1 trial
  29. MSC and PRP

    Hospital Authority, Hong Kong

    Type 1 Diabetes Mellitus

    phase 2 mab active

    1 trial
  30. MSC-NTF cells transplantation (IM)

    BRAINSTORM CELL THERAPEUTICS INC.

    Amyotrophic Lateral Sclerosis

    phase 2 mab completed

    1 trial
  31. MSC-NTF-002-HMO-CTIL

    BRAINSTORM CELL THERAPEUTICS INC.

    Amyotrophic Lateral Sclerosis

    phase 2 mab completed

    1 trial
  32. MT-2-02

    Minoryx Therapeutics S.L.

    CEREBRAL X-LINKED ADRENOLEUKODYSTROPHY (CALD)

    phase 2 other active

    1 trial
  33. MT-2-04

    Minoryx Therapeutics S.L.

    Rett Syndrome

    phase 2 small molecule active

    1 trial
  34. MT-401

    Marker Therapeutics

    Acute Myeloid Leukemia

    phase 2 small molecule terminated

    1 trial
  35. MVA-NP+M1

    Barinthus Biotherapeutics plc.

    Influenza

    phase 2 mab completed

    2 trials
  36. MVA85A

    United Therapeutics Europe Ltd

    Tuberculosis

    phase 2 mab completed

    1 trial
  37. MZE829

    Maze Therapeutics

    Proteinuric Kidney Disease

    phase 2 small molecule active

    1 trial
  38. MZE829

    Maze Therapeutics

    APOL1 Kidney Disease (AKD)

    phase 2 small molecule active

    1 trial
  39. MaZiRenWan (MZRW)

    Hong Kong Baptist University

    Functional Gastrointestinal Disorders

    phase 2 small molecule completed

    1 trial
  40. MaaT033 capsule

    Regeneron UK Limited

    NSCLC (Advanced Non-small Cell Lung Cancer)

    phase 2 small molecule active

    1 trial
  41. Magnesium Sulfate

    United Therapeutics Europe Ltd

    Traumatic Brain Injury

    phase 2 small molecule terminated

    1 trial
  42. Maralixibat

    Mirum Pharmaceuticals International B.V.

    Progressive Familial Intrahepatic Cholestasis

    phase 2 small molecule completed

    1 trial
  43. Maralixibat

    Mirum Pharmaceuticals International B.V.

    Biliary Atresia

    phase 2 small molecule completed

    1 trial
  44. Maralixibat

    Mirum Pharmaceuticals International B.V.

    Cholestatic Liver Disease

    phase 2 small molecule completed

    1 trial
  45. Maralixibat

    Mirum Pharmaceuticals International B.V.

    Intrahepatic Cholestasis of Pregnancy

    phase 2 small molecule active

    1 trial
  46. Maraviroc

    Pfizer

    Arthritis, Rheumatoid

    phase 2 small molecule terminated

    1 trial
  47. Maribavir

    Takeda

    Cytomegalovirus Infection

    phase 2 small molecule completed

    1 trial
  48. Marijuana blunt

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Dependence

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.