Friday, July 10, 2026

Intelligence · Clinical pipeline

Rare disease · Phase II

Rare disease programs at Phase II — ClinicalTrials.gov pipeline intelligence.

Programs 6

Quick answer

Rare disease Phase II programs: NovaPharmaNews indexes 6 matching clinical development programs from ClinicalTrials.gov with sponsor, modality, and NCT cross-links.

Top sponsors

Pipeline programs

  1. AXS-05 (dextromethorphan-bupropion)

    Axsome Therapeutics

    Treatment Resistant Depression

    phase 2 small molecule terminated

    1 trial
  2. Almonertinib 110 MG

    Chinese University of Hong Kong

    Rare Tumor

    phase 2 small molecule active

    1 trial
  3. Dextromethorphan-Bupropion

    Axsome Therapeutics

    Major Depressive Disorder (MDD)

    phase 2 small molecule active

    1 trial
  4. Nintedanib,Dextromethorphan

    The First People's Hospital of Lianyungang

    Idiopathic Pulmonary Fibrosis (IPF)

    phase 2 small molecule active

    1 trial
  5. Rapamune 1 mg/mL oral solution

    Tour Hekla

    Lingual microcystic lymphatic malformations (LMLMs) are rare congenital vascular malformations, presenting as clusters of cysts filled with lymph fluid or blood. They are responsible for a heavy burden even with small well-limited lesions because of oozing, bleeding, infections, or even speech, chewing or breathing impairment. Pain and aesthetic prejudice are also frequently reported

    phase 2 small molecule active

    1 trial
  6. WO42178

    Hoffmann-La Roche

    Persistent or Recurrent Rare Epithelial Ovarian Tumors

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many rare disease Phase II programs exist?

6 programs match both the therapeutic area and stage filters in our published index.