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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 1 of 151

  1. "Endostar"

    The First People's Hospital of Lianyungang

    Esophageal

    phase 2 small molecule terminated

    1 trial

  2. (+)-α-DIHYDROTETRABENAZINE

    Lacuna Pharma Pty Ltd

    Tardive dyskinesia

    phase 2 small molecule active

    1 trial

  3. (+)-α-DIHYDROTETRABENAZINE

    Lacuna Pharma Pty Ltd

    tardive dyskinesia

    phase 2 small molecule active

    1 trial

  4. (+)-α-DIHYDROTETRABENAZINE, ADE513 placebo

    Lacuna Pharma Pty Ltd

    Tardive dyskinesia

    phase 2 small molecule active

    1 trial

  5. (Z)-endoxifen

    ATOSSA THERAPEUTICS, INC.

    Breast Neoplasms

    phase 2 small molecule active

    1 trial

  6. -

    Disc Medicine

    Intrahepatic cholangiocarcinoma (iCCA)

    phase 2 small molecule active

    1 trial

  7. -

    Ningbo Cancer Hospital

    Unresectable intrahepatic cholangiocarcinoma

    phase 2 small molecule active

    1 trial

  8. -

    Talion

    Primary or advanced breast cancer LumA or ER+ Lobular subtypes.

    phase 2 small molecule active

    1 trial

  9. -

    Lacuna Pharma Pty Ltd

    Myocardial Infarction, Acute Heart Failure, Left Sided

    phase 2 small molecule active

    1 trial

  10. -

    The George Institute

    Cytomegalovirus infection post allogeneic allogeneic HLA-identical familial PHT

    phase 2 small molecule active

    1 trial

  11. -, Pred Forte 10 mg/ml colirio en suspensión

    AbbVie Deutschland GmbH & Co. KG

    platinum-resistant advanced high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancers.

    phase 2 small molecule active

    1 trial

  12. -aminosalicylic acid

    Ultragenyx UK Limited

    Ulcerative Colitis

    phase 2 small molecule completed

    1 trial

  13. 0% N2O

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 2 small molecule completed

    2 trials

  14. 0.2mg group

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Opioid Dependence

    phase 2 small molecule active

    1 trial

  15. 0.5% Ivermectin lotion

    United Therapeutics Europe Ltd

    Pediculosis Capitis

    phase 2 small molecule completed

    1 trial

  16. 0.59 mg fluocinolone acetonide intravitreal implant

    Bausch & Lomb Incorporated

    Diabetic Macular Edema

    phase 2 small molecule completed

    1 trial

  17. 0.9% NaCl 2000ml

    Universal Integrated

    Brain Infarct

    phase 2 small molecule completed

    1 trial

  18. 0.9% Sodium Chloride Injection

    GlaxoSmithKline

    Non-alcoholic Fatty Liver Disease

    phase 2 small molecule active

    1 trial

  19. 0.9% Sodium Chloride Injection, mRNA-3705

    Moderna Biotech Spain

    Isolated Methylmalonic Acidemia Due to Methylmalonyl-CoA Mutase Deficiency

    phase 2 small molecule active

    1 trial

  20. 0.9% Sodium chloride - inhalation solution

    Arrowhead Pharmaceuticals Ireland Limited

    Inflammatory Lung Disease

    phase 2 small molecule active

    1 trial

  21. 0.9% sodium chloride

    The First People's Hospital of Lianyungang

    Kidney Disease, Chronic

    phase 2 small molecule active

    1 trial

  22. 0.9% sodium chloride aqueous solution for IV infusion

    Chiesi Farmaceutici S.p.A

    Idiopathic pulmonary fibrosis (IPF)

    phase 2 small molecule active

    1 trial

  23. 0.9% sodium chloride, GADOTERIC ACID

    Eli Lilly Co.

    Relapsing Multiple Sclerosis

    phase 2 small molecule active

    1 trial

  24. 01-02-TL-375-015

    Takeda

    Drug Abuse

    phase 2 small molecule completed

    1 trial

  25. 1% tenofovir gel

    BRIGHT MINDS BIOSCIENCES INC.

    HIV Infections

    phase 2 small molecule completed

    1 trial

  26. 1-(3-(fluoro-18F)benzyl)guanidine ([18F]mFBG)

    Disc Medicine

    Pheochromocytoma – endocrine adrenal tumor

    phase 2 small molecule active

    1 trial

  27. 1. Intranasal oxytocin spray

    United Therapeutics Europe Ltd

    Autism Spectrum Disorder

    phase 2 small molecule active

    1 trial

  28. 1.6

    Disc Medicine

    HIV-1

    phase 2 small molecule active

    1 trial

  29. 1/BOB1

    Disc Medicine

    B-cell Acute Lymphoblastic Leukemia, Multiple Myeloma, Non-Hodgkin B-cell lymphoma

    phase 2 small molecule active

    1 trial

  30. 10 GE Xenokidney

    United Therapeutics Europe Ltd

    ESRD (End-Stage Renal Disease)

    phase 2 mab active

    1 trial

  31. 10 mg PRAX-114

    Chongqing Precision Biotech Co., Ltd

    Major Depressive Disorder

    phase 2 small molecule completed

    1 trial

  32. 10 mg PRAX-114

    Praxis Precision Medicines

    Major Depressive Disorder

    phase 2 small molecule completed

    1 trial

  33. 10 mg/kg CM-101

    Chemomab Therapeutics

    Systemic Sclerosis

    phase 2 small molecule on hold

    1 trial

  34. 100 mg PRAX-944

    Chongqing Precision Biotech Co., Ltd

    Essential Tremor

    phase 2 small molecule completed

    1 trial

  35. 100 μg KIO-301

    KIORA PHARMACEUTICALS INC

    Retinitis Pigmentosa

    phase 2 small molecule active

    1 trial

  36. 100U EV71 vaccine with adjuvant

    Sinovac Research and Development Co.,

    Infection, Viral, Enterovirus

    phase 2 mab completed

    1 trial

  37. 101090401IN

    Santen Oy

    Fuchs Endothelial Corneal Dystrophy (FECD)

    phase 2 small molecule active

    1 trial

  38. 10353

    Disc Medicine

    Patients with metastatic solid tumours, where clinical data has shown a rationale for ICI therapy.

    phase 2 small molecule active

    1 trial

  39. 10mg DS-8500a tablet

    Daiichi Sankyo

    Type 2 Diabetes Mellitus

    phase 2 small molecule completed

    1 trial

  40. 111-205

    BioMarin Pharmaceutical Australia Pty Ltd

    Achondroplasia

    phase 2 small molecule active

    1 trial

  41. 111-208

    BioMarin Pharmaceutical Australia Pty Ltd

    Achondroplasia

    phase 2 small molecule active

    1 trial

  42. 111-210

    BioMarin Pharmaceutical Australia Pty Ltd

    Idiopathic Short Stature (ISS)

    phase 2 small molecule active

    1 trial

  43. 111-211

    BioMarin Pharmaceutical Australia Pty Ltd

    Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome

    phase 2 small molecule active

    1 trial

  44. 111-212

    BioMarin Pharmaceutical Australia Pty Ltd

    Hypochondroplasia

    phase 2 small molecule active

    1 trial

  45. 114055

    GlaxoSmithKline

    Systemic Lupus Erythematosus

    phase 2 small molecule active

    1 trial

  46. 12.5mg sunitinib with Cisplatin and Gemcitabine

    Hospital Authority, Hong Kong

    Nasopharyngeal Carcinoma

    phase 2 small molecule completed

    1 trial

  47. 12916

    Bayer AG

    "Patients with interstitial lung disease associated pulmonary hypertension"

    phase 2 other active

    1 trial

  48. 1366-0055

    Boehringer Ingelheim

    clinically significant portal hypertension (CSPH) in decompensated cirrhosis due to non-cholestatic liver disease

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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