Neurology & CNS · Phase II

Top sponsors

• BRIGHT MINDS BIOSCIENCES 13 programs
• United Therapeutics Europe 12 programs
• Chinese Academy of 11 programs
• Teva Pharma 11 programs
• Jazz Pharmaceuticals Ireland 10 programs
• Acadia Pharmaceuticals 9 programs
• HOFFMANN-LA ROCHE 9 programs
• George Institute for 8 programs
• SUPERNUS PHARMACEUTICALS 8 programs
• Cognition Therapeutics 7 programs
• Takeda 7 programs
• Anaxis Pharma 6 programs

1. 0.9% sodium chloride, GADOTERIC ACID

   Eli Lilly Co.

   Relapsing Multiple Sclerosis

   phase 2 · small molecule · active

   1 trial →

2. 1462rot25ct

   Lacuna Pharma Pty Ltd

   Parkinson's disease

   phase 2 · small molecule · active

   1 trial →

3. 18870

   Disc Medicine

   Chronic obstructive pulmonary disease (COPD), amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), and atypical Parkinson disorder (APD), particularly multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and corticobasal syndrome (CBS).

   phase 2 · small molecule · active

   1 trial →

4. 18F-92

   The First People's Hospital of Lianyungang

   Alzheimer's Disease

   phase 2 · small molecule · active

   1 trial →

5. 18FMC225_FPG

   Fondazione Telethon ETS

   depression

   phase 2 · small molecule · active

   1 trial →

6. 219867

   GlaxoSmithKline

   Alzheimer's Disease

   phase 2 · small molecule · active

   1 trial →

7. 223646

   GlaxoSmithKline

   Alzheimer's Disease

   phase 2 · other · active

   1 trial →

8. 283PD201

   Biogen

   Parkinson's Disease

   phase 2 · small molecule · active

   1 trial →

9. 5-(1-(2-[18F] fluoroethoxy))-[3-(6 for Alzheimers Disease, sporadic Ce…

   Disc Medicine

   Alzheimers Disease, sporadic Cerebral Amyloid Angiopathy, Parkinson

   phase 2 · small molecule · active

   1 trial →

10. 64042056ALZ2001

    Janssen-Cilag International N.V.

    Preclinical Alzheimer’s Disease

    phase 2 · small molecule · active

    1 trial →

11. A phase 2 trial assessing Ifenprodil as a ReM... for Multiple sclerosis

    Pari Pharma GmbH

    Multiple sclerosis

    phase 2 · other · active

    1 trial →

12. ABBV-552

    AbbVie

    Alzheimer's Disease (AD)

    phase 2 · small molecule · completed

    1 trial →

13. ACP-103

    Acadia Pharmaceuticals B.V.

    Schizophrenia

    phase 2 · small molecule · completed

    1 trial →

14. ACP-104

    Acadia Pharmaceuticals B.V.

    Schizophrenia

    phase 2 · small molecule · completed

    2 trials →

15. ACT-1004-1239 matching placebo

    Lacuna Pharma Pty Ltd

    Progressive multiple sclerosis (MS)

    phase 2 · small molecule · active

    1 trial →

16. ACT16753

    Sanofi-aventis Healthcare Pty Ltd

    Multiple sclerosis

    phase 2 · small molecule · active

    1 trial →

17. ACT16877

    Sanofi-aventis Healthcare Pty Ltd

    Multiple Sclerosis

    phase 2 · small molecule · active

    1 trial →

18. ACU193-201

    Acumen Pharmaceuticals

    Early Alzheimer’s Disease (Mild Cognitive Impairment and Mild Dementia Due to Alzheimer’s Disease)

    phase 2 · small molecule · active

    1 trial →

19. ADX48621

    Addex Therapeutics

    Parkinson's Disease

    phase 2 · small molecule · completed

    1 trial →

20. AH0003

    Lacuna Pharma Pty Ltd

    Alzheimer’s Disease

    phase 2 · small molecule · active

    1 trial →

21. ALECTINIB

    Hoffmann-La Roche

    ALK fusion-positive extracranial solid or primary CNS tumors who have progressed following prior treatment or who have no satisfactory treatment available

    phase 2 · small molecule · active

    1 trial →

22. AMBROXOL , Microcrystalline cellulose

    Disc Medicine

    Parkinson's disease

    phase 2 · small molecule · active

    1 trial →

23. AMX0035

    Amylyx Pharmaceuticals EMEA B.V.

    Alzheimer Disease

    phase 2 · small molecule · completed

    1 trial →

24. ARICEPT 10mg comprimidos recubiertos con película

    The George Institute

    Parkinson's disease

    phase 2 · small molecule · active

    1 trial →

25. ARO-MAPT-SC

    Arrowhead Pharmaceuticals Ireland Limited

    Alzheimer Disease

    phase 2 · small molecule · active

    1 trial →

26. ATA188

    Evidence Based Cataract Study Group

    Primary Progressive Multiple Sclerosis

    phase 2 · mab · terminated

    1 trial →

27. AV-101

    Vistagen Therapeutics

    Parkinson Disease

    phase 2 · small molecule · active

    1 trial →

28. AXS-05

    Axsome Therapeutics

    Treatment Resistant Depression

    phase 2 · small molecule · completed

    1 trial →

29. AXS-05 (dextromethorphan-bupropion)

    Axsome Therapeutics

    Treatment Resistant Depression

    phase 2 · small molecule · terminated

    1 trial →

30. Active Treatment- CT1812 100 mg

    COGNITION THERAPEUTICS INC

    Alzheimer Disease

    phase 2 · small molecule · completed

    1 trial →

31. Active drug: pimavanserin 17mg (2 strength tablets)

    Acadia Pharmaceuticals B.V.

    Parkinson Disease

    phase 2 · small molecule · completed

    1 trial →

32. Amiloride

    United Therapeutics Europe Ltd

    Secondary Progressive Multiple Sclerosis

    phase 2 · small molecule · completed

    1 trial →

33. Aplindore

    LIGAND PHARMACEUTICALS INC

    Early Stage Parkinson's Disease

    phase 2 · small molecule · completed

    1 trial →

34. Armodafinil

    Teva Pharma GmbH

    Bipolar I Depression

    phase 2 · small molecule · completed

    1 trial →

35. Atomoxetin STADA 40 mg Hartkapseln, GELATIN

    Pari Pharma GmbH

    Healthy subjects with no neurological or psychiatric disorders

    phase 2 · small molecule · active

    1 trial →

36. Azeliragon

    vTv Therapeutics

    Alzheimer Disease

    phase 2 · small molecule · terminated

    1 trial →

37. B-CIT and SPECT imaging

    United Therapeutics Europe Ltd

    Parkinson Disease

    phase 2 · small molecule · completed

    1 trial →

38. BHV-7000, BHV-7000

    Biohaven Bioscience Ireland Limited

    Refractory Focal Onset Epilepsy

    phase 2 · small molecule · active

    1 trial →

39. BHV7000-302

    Biohaven Bioscience Ireland Limited

    Refractory Focal Onset Epilepsy

    phase 2 · small molecule · active

    1 trial →

40. BIIB122 225 mg

    Denali Therapeutics

    Parkinson Disease

    phase 2 · small molecule · active

    1 trial →

41. BIIB122, Placebo to BIIB122

    Denali Therapeutics

    Parkinson’s disease

    phase 2 · small molecule · active

    1 trial →

42. BMB-101

    BRIGHT MINDS BIOSCIENCES INC.

    Absence Epilepsy

    phase 2 · small molecule · active

    1 trial →

43. BP42155

    Hoffmann-La Roche

    Alzheimer's disease

    phase 2 · small molecule · active

    1 trial →

44. BP44745

    Hoffmann-La Roche

    Alzheimer’s Disease

    phase 2 · small molecule · active

    1 trial →

45. BP46016

    Hoffmann-La Roche

    Progressive Forms of Multiple Sclerosis (PMS)

    phase 2 · small molecule · active

    1 trial →

46. Berubicin hydrochloride

    Rani Therapeutics Holdings

    central nervous system (CNS) lymphomas

    phase 2 · small molecule · active

    1 trial →

47. Bone marrow mesenchymal stem cells autologous

    Lxo Ireland Designated Activity Company

    Multiple Sclerosis

    phase 2 · other · completed

    1 trial →

48. Bupropion

    BRIGHT MINDS BIOSCIENCES INC.

    Schizophrenia and Disorders With Psychotic Features

    phase 2 · small molecule · completed

    1 trial →

Frequently asked questions