Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Leukine for Ovarian cancer

    Nordic Bioscience A/S

    Ovarian cancer

    phase 2 small molecule active

    1 trial
  2. Leukocyte-Poor Platelet Rich Plasma (LP-PRP)

    United Therapeutics Europe Ltd

    Osteoarthritis, Knee

    phase 2 mab active

    1 trial
  3. Leuprolide acetate

    Voyager Therapeutics

    Alzheimer Disease

    phase 2 small molecule completed

    2 trials
  4. Leuprolide or goserelin

    NORTHWEST BIOTHERAPEUTICS INC

    Cancer

    phase 2 small molecule completed

    1 trial
  5. Leuprorelin

    Takeda

    Prostatic Neoplasms

    phase 2 small molecule completed

    1 trial
  6. Leuprorelin (GF)

    Takeda

    Uterine Fibroids

    phase 2 small molecule completed

    1 trial
  7. Levact 2 for Relapsed/refractory large B-cel…

    The George Institute

    Relapsed/refractory large B-cell non-Hodgkin lymphoma, mantle cell lymphoma, and follicular lymphoma

    phase 2 small molecule active

    1 trial
  8. Levoleucovorin Calcium

    United Therapeutics Europe Ltd

    Autism Spectrum Disorder

    phase 2 small molecule active

    1 trial
  9. Levosimendan

    TENAX THERAPEUTICS, INC.

    Hypertension Pulmonary Secondary

    phase 2 small molecule completed

    1 trial
  10. Levosimendan

    TENAX THERAPEUTICS, INC.

    Hypertension Pulmonary Secondary Heart Failure

    phase 2 small molecule completed

    1 trial
  11. Levothyroxine sodium new formulation

    Takeda

    Hypothyroidism

    phase 2 small molecule completed

    1 trial
  12. LiPlaCis

    Allarity Therapeutics

    Phase 1: Advanced or Refractory Solid Tumours

    phase 2 small molecule completed

    1 trial
  13. Libmeldy 2-10 x 10^6 cells/mL dispersion for infusion

    Orchard Therapeutics (Netherlands) B.V.

    Metachromatic Leukodystrophy (MLD)

    phase 2 small molecule active

    1 trial
  14. Lidocaine HCl

    BRIGHT MINDS BIOSCIENCES INC.

    Postherpetic Neuralgia

    phase 2 small molecule active

    1 trial
  15. Lidocaine Hydrochloride, Injectable

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Postoperative Chronic Pain

    phase 2 small molecule active

    1 trial
  16. Lidocaína B. Braun /ml solución inyectable for headache pain related to SAH, S…

    The George Institute

    headache pain related to SAH, Spontaneous subarachnoid hemorrhage

    phase 2 small molecule active

    1 trial
  17. Lifei Qingchang Granules

    The First People's Hospital of Lianyungang

    Bronchiectasis

    phase 2 small molecule active

    1 trial
  18. Lifileucel

    Iovance Biotherapeutics B.V.

    Endometrial Cancer

    phase 2 mab active

    1 trial
  19. Lifileucel

    Iovance Biotherapeutics B.V.

    Metastatic Melanoma

    phase 2 mab completed

    2 trials
  20. Lifileucel

    Iovance Biotherapeutics B.V.

    Melanoma (Skin Cancer)

    phase 2 mab active

    1 trial
  21. Lifitegrast

    Takeda

    Dry Eye

    phase 2 small molecule completed

    1 trial
  22. Lifitegrast

    Takeda

    Allergic Conjunctivitis

    phase 2 small molecule completed

    1 trial
  23. Light-activated AU-011

    Aura Biosciences

    Uveal Melanoma

    phase 2 small molecule completed

    1 trial
  24. Linaclotide 145 micrograms

    IRONWOOD PHARMACEUTICALS INC

    Opioid-Induced Constipation

    phase 2 small molecule completed

    1 trial
  25. Linaclotide Acetate

    IRONWOOD PHARMACEUTICALS INC

    Irritable Bowel Syndrome With Constipation

    phase 2 small molecule completed

    1 trial
  26. Linaclotide Dose A

    IRONWOOD PHARMACEUTICALS INC

    Irritable Bowel Syndrome With Constipation

    phase 2 small molecule terminated

    1 trial
  27. Linezolid

    BRIGHT MINDS BIOSCIENCES INC.

    Pulmonary Tuberculosis

    phase 2 small molecule completed

    1 trial
  28. Linezolid

    BRIGHT MINDS BIOSCIENCES INC.

    Tuberculosis, Meningeal

    phase 2 small molecule completed

    1 trial
  29. Linperlisib combination with obinutuzumab

    The First People's Hospital of Lianyungang

    Lymphoma

    phase 2 small molecule active

    1 trial
  30. Lintuzumab-Ac225

    Actinium Pharmaceuticals

    Acute Myeloid Leukemia

    phase 2 mab active

    2 trials
  31. Linvoseltamab

    Regeneron UK Limited

    Smoldering Multiple Myeloma (SMM)

    phase 2 small molecule active

    1 trial
  32. Linvoseltamab

    Regeneron UK Limited

    Recurrent Multiple Myeloma

    phase 2 mab active

    1 trial
  33. Linvoseltamab

    Regeneron UK Limited

    Relapsed/Refractory Multiple Myeloma

    phase 2 small molecule active

    1 trial
  34. Linvoseltamab

    Regeneron UK Limited

    Relapsed/Refractory Systemic Light Chain Amyloidosis

    phase 2 small molecule active

    1 trial
  35. Linvoseltamab

    Regeneron UK Limited

    Monoclonal Gammopathy of Undetermined Significance (MGUS)

    phase 2 small molecule active

    1 trial
  36. Lipid Lowering Medication

    Grace Therapeutics

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial
  37. Liposomal Annamycin

    Moleculin Biotech

    Leukemia, Myeloid, Acute

    phase 2 small molecule completed

    3 trials
  38. Liposomal Annamycin (L-Annamycin)

    Moleculin Biotech

    Sarcoma,Soft Tissue

    phase 2 small molecule completed

    1 trial
  39. Liposomal Bupivacaine

    United Therapeutics Europe Ltd

    Femoral Fractures

    phase 2 small molecule terminated

    1 trial
  40. Liposomal Irinotecan

    United Therapeutics Europe Ltd

    Oncology

    phase 2 small molecule completed

    1 trial
  41. Liposomal bupivacaine

    United Therapeutics Europe Ltd

    Blunt Chest Wall Trauma

    phase 2 small molecule completed

    1 trial
  42. Liposomal doxorubicin hydrochloride

    Teva Pharma GmbH

    Breast Cancer

    phase 2 small molecule completed

    1 trial
  43. Liposomal irinotecan

    The First People's Hospital of Lianyungang

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule active

    1 trial
  44. Liposome bupivacaine

    Pacira Ireland Limited

    Hallux Valgus (Bunions)

    phase 2 small molecule completed

    1 trial
  45. Liposome bupivacaine + bupivacaine

    Pacira Ireland Limited

    Dupuytren's Contracture of the Hand (Viking's Disease)

    phase 2 small molecule completed

    1 trial
  46. Liposome-encapsulated Daunorubicin-Cytarabine

    Jazz Pharmaceuticals Ireland Limited

    Essential Thrombocythemia

    phase 2 small molecule terminated

    1 trial
  47. Liposome-encapsulated Daunorubicin-Cytarabine

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome

    phase 2 small molecule active

    1 trial
  48. Liposome-encapsulated Daunorubicin-Cytarabine

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia

    phase 2 small molecule active

    2 trials

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.