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Intelligence Β· Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. ST-920

    SANGAMO THERAPEUTICS, INC

    Fabry Disease (X-linked lysosomal storage disease).

    phase 2 small molecule active

    1 trial

  2. STAT3 Inhibitor WP1066

    Moleculin Biotech

    Glioblastoma, IDH-Wildtype

    phase 2 small molecule active

    1 trial

  3. STC-15 in combination with toripalimab

    Coherus Oncology

    Solid Tumor

    phase 2 other active

    1 trial

  4. STK-001 - Single Ascending Doses

    Stoke Therapeutics

    Dravet Syndrome

    phase 2 small molecule completed

    1 trial

  5. STN1010904, Placebo (vehicle), STN1010904

    Santen Oy

    Fuchs Endothelial Corneal Dystrophy (FECD)

    phase 2 small molecule active

    1 trial

  6. STRO-002

    SUTRO BIOPHARMA, INC.

    Neoplasm Malignant

    phase 2 mab completed

    1 trial

  7. SUB01423MIG, SUB01423MIG, Colesevelam-matching placebo film-coated oral tablets (Unit Dose C)., Colesevelam-matching placebo film-coated oral tablets (Unit Dose D)., DISSENTEN 2 mg compresse

    Monte Rosa Therapeutics

    Bile acid diarrhoea

    phase 2 small molecule active

    1 trial

  8. SUL-238, Identical to test product except without active substance

    Sana Biotechnology

    Parkinson’s Disease

    phase 2 small molecule active

    1 trial

  9. SV-BR-1-GM

    BriaCell Therapeutics

    Breastcancer

    phase 2 mab completed

    1 trial

  10. SX-682

    United Therapeutics Europe Ltd

    Metastatic Castrate-Resistant Prostate Cancer (mCRPC)

    phase 2 small molecule active

    1 trial

  11. SY-1425, AZACITIDINE

    Lacuna Pharma Pty Ltd

    Acute Myeloid Leukemia (AML) Myelodysplastic Syndrome (MDS)

    phase 2 small molecule active

    1 trial

  12. SYNTOCINON 40 i.e./ml prΕ‘ilo za nos, raztopina, Oxytocin Placebo

    The George Institute

    schizophrenia or other primary psychotic disorders (SSD)

    phase 2 small molecule active

    1 trial

  13. SYR-619

    Takeda

    Diabetes Mellitus

    phase 2 small molecule terminated

    1 trial

  14. Sabin-Based Inactivated Poliomyelitis Vaccine (sIPV)

    Takeda

    Poliomyelitis

    phase 2 mab terminated

    1 trial

  15. Sacituzumab Tirumotecan

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Extensive-Stage Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  16. Sacituzumab Tirumotecan and Limertinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    EGFR-mutant Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  17. Sacituzumab Tirumotecan in combination with tislelizumab

    The First People's Hospital of Lianyungang

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  18. Sacituzumab tirumotecan

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    TNBC - Triple-Negative Breast Cancer

    phase 2 small molecule active

    1 trial

  19. Safety and efficacy of IMM-101 combined with stereotactic radiotherapy in patients with limited metastatic pancreatic cancer (MEPANC-1)

    Disc Medicine

    Limited metastatic pancreatic cancer

    phase 2 other active

    1 trial

  20. Sandwich stratergy

    The First People's Hospital of Lianyungang

    Acute Lymphobkastic Leukemia

    phase 2 other active

    1 trial

  21. Saphnelo 300 mg concentrate for solution for infusion, Saphnelo placebo

    Disc Medicine

    Sjogren's disease

    phase 2 small molecule active

    1 trial

  22. Sapropterin

    BioMarin Pharmaceutical Australia Pty Ltd

    Phenylketonuria

    phase 2 small molecule terminated

    1 trial

  23. Sapropterin

    BioMarin Pharmaceutical Australia Pty Ltd

    GTP Cyclohydrolase Deficiency

    phase 2 small molecule completed

    1 trial

  24. Sapropterin Dihydrochloride

    BioMarin Pharmaceutical Australia Pty Ltd

    Intermittent Claudication

    phase 2 small molecule completed

    1 trial

  25. Sapropterin Dihydrochloride

    BioMarin Pharmaceutical Australia Pty Ltd

    Endothelial Dysfunction

    phase 2 small molecule completed

    1 trial

  26. Sapropterin Dihydrochloride

    BioMarin Pharmaceutical Australia Pty Ltd

    Sickle Cell Disease

    phase 2 small molecule completed

    1 trial

  27. Sarcosine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Schizophrenias

    phase 2 small molecule completed

    1 trial

  28. Sarcosine and D-serine

    Hospital Authority, Hong Kong

    Schizophrenias

    phase 2 small molecule completed

    1 trial

  29. Sargramostim

    Hospital Authority, Hong Kong

    COVID

    phase 2 small molecule completed

    1 trial

  30. Sargramostim

    United Therapeutics Europe Ltd

    COVID-19

    phase 2 small molecule completed

    1 trial

  31. Sargramostim

    United Therapeutics Europe Ltd

    Covid19

    phase 2 small molecule completed

    1 trial

  32. Sargramostim

    Hospital Authority, Hong Kong

    Pulmonary Alveolar Proteinosis, Autoimmune

    phase 2 small molecule completed

    1 trial

  33. Sarilumab

    Regeneron UK Limited

    Morphea, Plaque Form

    phase 2 small molecule terminated

    1 trial

  34. Sarilumab

    Regeneron UK Limited

    Ankylosing Spondylitis

    phase 2 small molecule terminated

    2 trials

  35. Sarilumab

    Regeneron UK Limited

    Juvenile Idiopathic Arthritis

    phase 2 small molecule completed

    1 trial

  36. Sarilumab SAR153191 (REGN88)

    Regeneron UK Limited

    Juvenile Idiopathic Arthritis

    phase 2 small molecule active

    1 trial

  37. Saruparib

    AstraZeneca AB

    Advanced/Recurrent Ovarian cancer

    phase 2 small molecule active

    1 trial

  38. Saruparib, Camizestrant, Datopotamab deruxtecan, PACLITAXEL , Saruparib, DS-8201a, Saruparib, Saruparib

    AstraZeneca AB

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  39. Saruparib, ZYTIGA 500 mg film-coated tablets, Erleada 60 mg film-coated tablets, Saruparib, Xtandi - 40 mg soft capsules, Prednisone Mylan Pharma 5 mg compresse, NUBEQA 300 mg film-coated tablets, Saruparib

    AstraZeneca AB

    Metastatic Prostate Cancer

    phase 2 small molecule active

    1 trial

  40. Sasanlimab Prefilled syringe

    Pfizer

    Carcinoma, Non-Small-Cell Lung

    phase 2 small molecule terminated

    1 trial

  41. Sativex

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 2 small molecule completed

    1 trial

  42. Sativex

    Jazz Pharmaceuticals Ireland Limited

    Cancer

    phase 2 small molecule completed

    2 trials

  43. Savolitinib

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  44. Savolitinib, TAGRISSO 40 mg film-coated tablets, TAGRISSO 80 mg film-coated tablets, Savolitinib

    AstraZeneca AB

    EGFRm+ and MET+, Locally Advanced or Metastatic Non Small Cell Lung Cancer.

    phase 2 small molecule active

    1 trial

  45. Savolitinib, TAGRISSO 80 mg film-coated tablets, TAGRISSO 40 mg film-coated tablets, TAGRISSO 80 mg film-coated tablets, Savolitinib, TAGRISSO 40 mg film-coated tablets, TAGRISSO 40 mg film-coated tablets, TAGRISSO 40 mg film-coated tablets, TAGRISSO 80 mg film-coated tablets, TAGRISSO 80 mg film-coated tablets

    AstraZeneca AB

    EGFRm+ and MET+, Locally Advanced or Metastatic Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  46. Saxenda 6 mg/mL solution for injection in pre-filled pen, Saxenda 6 mg/mL solution for injection in pre-filled pen, Placebo for PF-07976016, Saxenda 6 mg/mL solution for injection in pre-filled pen

    Pfizer Australia Pty Ltd

    Obesity, Overweight

    phase 2 small molecule active

    1 trial

  47. Scaling and root planing, and Septilin for 7 days

    BRIGHT MINDS BIOSCIENCES INC.

    Chronic Periodontitis

    phase 2 small molecule completed

    1 trial

  48. Scemblix 20 mg film-coated tablets, Tasigna 200 mg hard capsules, Scemblix 40 mg film-coated tablets, Tasigna 150 mg hard capsules

    Novartis Pharmaceuticals

    Chronic myeloid leukemia

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources Β· All pipeline programs

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