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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Selinexor 60 mg

    Karyopharm Therapeutics Inc

    Myelofibrosis

    phase 2 small molecule active

    1 trial

  2. Selpercatinib

    Eli Lilly and Company

    Medullary Thyroid Cancer

    phase 2 small molecule active

    1 trial

  3. Selpercatinib Monotherapy

    United Therapeutics Europe Ltd

    Differentiated Thyroid Cancer

    phase 2 small molecule active

    1 trial

  4. Selumetinib

    United Therapeutics Europe Ltd

    Malignant Peripheral Nerve Sheath Tumors

    phase 2 small molecule completed

    1 trial

  5. Selumetinib

    United Therapeutics Europe Ltd

    Metastatic Thyroid Gland Carcinoma

    phase 2 small molecule completed

    1 trial

  6. Semaglutide

    United Therapeutics Europe Ltd

    Cardiomyopathy

    phase 2 small molecule active

    1 trial

  7. Semaglutide

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 2 small molecule active

    1 trial

  8. Semaglutide (Rybelsus®)

    The First People's Hospital of Lianyungang

    Obesity-related Male Infertility

    phase 2 small molecule active

    1 trial

  9. Semaglutide Pen Injector

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder

    phase 2 small molecule active

    1 trial

  10. Senicapoc

    BRIGHT MINDS BIOSCIENCES INC.

    Mild Cognitive Impairment

    phase 2 small molecule active

    1 trial

  11. Serdexmethylphenidate

    ZEVRA THERAPEUTICS, INC.

    Idiopathic Hypersomnia

    phase 2 small molecule completed

    1 trial

  12. Serelaxin

    Novartis Pharmaceuticals

    Acute Heart Failure

    phase 2 small molecule completed

    1 trial

  13. Serlopitant

    VYNE Therapeutics

    Pruritus

    phase 2 small molecule terminated

    1 trial

  14. Serlopitant High Dose

    VYNE Therapeutics

    Pruritus

    phase 2 small molecule completed

    1 trial

  15. Serlopitant Tablet

    VYNE Therapeutics

    Epidermolysis Bullosa

    phase 2 small molecule completed

    1 trial

  16. SerpinPC

    Centessa Pharmaceuticals plc

    Hemophilia B with Inhibitor

    phase 2 small molecule terminated

    1 trial

  17. Serplulimab

    The First People's Hospital of Lianyungang

    Colorectal Cancer (Diagnosis)

    phase 2 small molecule active

    1 trial

  18. Serplulimab

    The First People's Hospital of Lianyungang

    HER2-positive Gastric Cancer

    phase 2 small molecule active

    1 trial

  19. Serplulimab

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 2 small molecule active

    1 trial

  20. Serratus Plane block (single injection)

    The First People's Hospital of Lianyungang

    Serratus Plane Block

    phase 2 other active

    1 trial

  21. Sertraline

    BRIGHT MINDS BIOSCIENCES INC.

    Alcoholism

    phase 2 small molecule terminated

    1 trial

  22. Sertraline

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  23. Sertraline combined with Lactobacillus crispatus

    The First People's Hospital of Lianyungang

    Major Depressive Disorder (MDD)

    phase 2 other active

    1 trial

  24. Sertraline+Antibiotic (penicillin/azithromycin)

    CNS Pharmaceuticals

    Pandas

    phase 2 small molecule terminated

    1 trial

  25. Setmelanotide

    Rhythm Pharmaceuticals Netherlands B.V.

    Overweight

    phase 2 small molecule completed

    1 trial

  26. Setmelanotide

    Rhythm Pharmaceuticals Netherlands B.V.

    Prader-Willi Syndrome

    phase 2 small molecule active

    2 trials

  27. Setmelanotide

    Rhythm Pharmaceuticals Netherlands B.V.

    Overweight and Obesity

    phase 2 small molecule completed

    1 trial

  28. Setmelanotide

    Rhythm Pharmaceuticals Netherlands B.V.

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial

  29. Setmelanotide

    Rhythm Pharmaceuticals Netherlands B.V.

    Genetic Obesity

    phase 2 small molecule completed

    2 trials

  30. Sevasemten

    Edgewise Therapeutics

    Becker Muscular Dystrophy

    phase 2 small molecule active

    2 trials

  31. Sevasemten 10 mg

    Edgewise Therapeutics

    Becker Muscular Dystrophy

    phase 2 small molecule active

    1 trial

  32. Sevasemten Dose 1

    Edgewise Therapeutics

    Duchenne Muscular Dystrophy

    phase 2 small molecule active

    2 trials

  33. Short-term Pre-OPerative Durvalumab (MEDI 4736) in early small triple negative breast cancer patients (POP-Durva)

    The George Institute

    Untreated small triple negative breast cancer

    phase 2 other active

    1 trial

  34. Sialic Acid Extended Release (SA-ER)

    Ultragenyx UK Limited

    GNE Myopathy

    phase 2 small molecule completed

    1 trial

  35. Sibeprenlimab, Sibeprenlimab placebo

    Otsuka Beijing Research Institute

    Treatment of Sjögren’s disease

    phase 2 small molecule active

    1 trial

  36. Sigvotatug vedotin, PF-08634404

    Pfizer Australia Pty Ltd

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  37. Sildenafil

    United Therapeutics Europe Ltd

    Scleroderma

    phase 2 small molecule active

    1 trial

  38. Sildenafil 50 mg Oral Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Erectile Dysfunction

    phase 2 small molecule completed

    1 trial

  39. Sildenafil Citrate

    United Therapeutics Europe Ltd

    Edema, Pulmonary

    phase 2 small molecule completed

    1 trial

  40. Silodosin

    Hospital Authority, Hong Kong

    Premature Ejaculation

    phase 2 small molecule active

    1 trial

  41. Siltuximab

    Janssen Cilag International NV

    Multicentric Castleman's Disease

    phase 2 small molecule completed

    1 trial

  42. Siltuximab

    United Therapeutics Europe Ltd

    Schwannomatosis

    phase 2 small molecule active

    1 trial

  43. Silycus®

    Istituto Gentili S.r.l.

    Cushing's disease

    phase 2 small molecule active

    1 trial

  44. Sindillimab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial

  45. Single Site Pacing

    Rhythm Pharmaceuticals Netherlands B.V.

    Acute Myocardial Infarction

    phase 2 other completed

    1 trial

  46. Single-centre, randomised, double-blind, split-face comparative design clinical trial to evaluate the efficacy and safety of the topical formulation with 4% hydroquinone and 0,025% tretinoin versus the formulation with 4% hydroquinone in patients with facial melasma

    Lacuna Pharma Pty Ltd

    facial melasma

    phase 2 other active

    1 trial

  47. Single-dose regimen of high dosage investigational sIPV

    Sinovac Research and Development Co.,

    Poliomyelitis

    phase 2 mab completed

    1 trial

  48. Sinovac Low-dosage PCV24

    Sinovac Research and Development Co.,

    Pneumococcal Infectious Disease

    phase 2 mab completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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