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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. SB-509

    SANGAMO THERAPEUTICS, INC

    Diabetes Mellitus, Type 1

    phase 2 small molecule completed

    4 trials

  2. SB-728-T

    SANGAMO THERAPEUTICS, INC

    HIV

    phase 2 gene therapy completed

    2 trials

  3. SB-728mR-T

    SANGAMO THERAPEUTICS, INC

    Human Immunodeficiency Virus (HIV)

    phase 2 gene therapy completed

    1 trial

  4. SB-913

    SANGAMO THERAPEUTICS, INC

    Mucopolysaccharidosis II

    phase 2 mab terminated

    1 trial

  5. SB497115

    GlaxoSmithKline

    Thrombocytopaenia

    phase 2 small molecule completed

    1 trial

  6. SB497115

    GlaxoSmithKline

    Purpura, Thrombocytopaenic, Idiopathic

    phase 2 small molecule completed

    1 trial

  7. SBRT combined with Nimotuzumab followed by Tislelizumab

    The First People's Hospital of Lianyungang

    Nasopharyngeal Cancinoma (NPC)

    phase 2 small molecule active

    1 trial

  8. SBRT combined with PD-1 inhibitors and thoracic hyperthermia

    The First People's Hospital of Lianyungang

    Stereotactic Body Radiation Therapy; PD-1 Inhibitor; Hyperthermia; NSCLC

    phase 2 other active

    1 trial

  9. SBRT combined with Tislelizumab followed by Tislelizumab

    Zibo Municipal Hospital

    NSCLC

    phase 2 small molecule active

    1 trial

  10. SCB01A

    Biotech Pharmaceutical Co.,

    Head and Neck Neoplasms

    phase 2 small molecule terminated

    1 trial

  11. SCD-044 Tablets 0.1mg, SCD-044 Tablets 0.6mg, SCD-044 Tablets 0.3mg, SCD-044 Tablets 1.0mg, placebo to match SCD-044 tablets

    Lacuna Pharma Pty Ltd

    atopic dermatitis

    phase 2 small molecule active

    1 trial

  12. SCD-044 Tablets 0.3mg, SCD-044 Tablets 0.6mg, SCD-044 Tablets 1.0mg, SCD-044 Tablets 0.1mg, placebo to match SCD-044 tablets

    Lacuna Pharma Pty Ltd

    moderate to severe plaque psoriasis

    phase 2 small molecule active

    1 trial

  13. SCENESSE 16 mg implant

    Clinuvel Europe Limited

    Erythropoietic Protoporphyria (EPP)

    phase 2 small molecule active

    1 trial

  14. SD-101 dermal cream (6%)

    BRIGHT MINDS BIOSCIENCES INC.

    Epidermolysis Bullosa

    phase 2 small molecule terminated

    1 trial

  15. SDREGN2810

    Regeneron UK Limited

    Advanced Non-Small Cell Lung Carcinoma

    phase 2 small molecule terminated

    1 trial

  16. SDX-101 (R-Etodolac)

    Teva Pharma GmbH

    Multiple Myeloma

    phase 2 small molecule terminated

    1 trial

  17. SDX-105

    Teva Pharma GmbH

    Non-Hodgkin's Lymphoma

    phase 2 small molecule completed

    1 trial

  18. SDZ MSL-109

    Ultragenyx UK Limited

    Cytomegalovirus Infections

    phase 2 small molecule completed

    1 trial

  19. SELINEXOR

    Karyopharm Therapeutics Inc

    Myelofibrosis

    phase 2 small molecule active

    1 trial

  20. SELPERCATINIB, SELPERCATINIB

    Wuhan Createrna Science and Technology Co., Ltd

    Male or female patients age 12 years or older with a locally advanced or metastatic solid tumor with evidence of a RET gene alteration in tumor and/or blood.

    phase 2 small molecule active

    1 trial

  21. SELPERCATINIB, Selpercatinib, Selpercatinib, SELPERCATINIB, Selpercatinib

    Wuhan Createrna Science and Technology Co., Ltd

    Pediatric Patients with Advanced RET-Altered Solid or Primary Central Nervous System Tumors

    phase 2 small molecule active

    1 trial

  22. SELUMETINIB, CASODEX 50 mg compresse rivestite con film, OLAPARIB

    Istituto Gentili S.r.l.

    Metastatic breast cancer

    phase 2 small molecule active

    1 trial

  23. SELUMETINIB, SELUMETINIB, Selumetinib, Selumetinib

    AstraZeneca AB

    Neurofibromatosis Type 1 (NF1) Related Plexiform Neurofibromas (PN)

    phase 2 small molecule active

    1 trial

  24. SENS-401 (R-Azasetron Besylate)

    Orion Laboratories Pty.

    Hearing Loss

    phase 2 small molecule completed

    1 trial

  25. SER-109

    Seres Therapeutics

    Clostridium Difficile

    phase 2 small molecule completed

    1 trial

  26. SERETIDE Rotacaps

    GlaxoSmithKline

    Asthma

    phase 2 small molecule completed

    1 trial

  27. SG+I

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    TNBC, Triple Negative Breast Cancer

    phase 2 small molecule active

    1 trial

  28. SGT-001

    Solid Biosciences

    Duchenne Muscular Dystrophy

    phase 2 gene therapy active

    1 trial

  29. SHJ002/Vehicle

    Biotech Pharmaceutical Co.,

    Dry Eye Disease

    phase 2 small molecule completed

    1 trial

  30. SHP611

    Shire

    Metachromatic Leukodystrophy (MLD)

    phase 2 small molecule active

    1 trial

  31. SHP611

    Takeda

    Metachromatic Leukodystrophy (MLD)

    phase 2 small molecule active

    1 trial

  32. SHP626

    Mirum Pharmaceuticals International B.V.

    Non-Alcoholic Steatohepatitis

    phase 2 small molecule completed

    3 trials

  33. SHP648

    Takeda

    Hemophilia B

    phase 2 gene therapy terminated

    1 trial

  34. SHP655

    Takeda

    Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

    phase 2 small molecule completed

    1 trial

  35. SHR-1139 Injection

    The First People's Hospital of Lianyungang

    Pyoderma Gangrenosum

    phase 2 small molecule active

    1 trial

  36. SHR-1210

    The First People's Hospital of Lianyungang

    Resectable Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial

  37. SHR-1210

    Hospital Authority, Hong Kong

    Renal Cell Carcinoma

    phase 2 mab active

    1 trial

  38. SHR-1701

    The First People's Hospital of Lianyungang

    Gastric Adenocarcinoma

    phase 2 small molecule active

    1 trial

  39. SHR-1701 Combined With Fluazopalil

    Hunan Province Tumor Hospital

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  40. SHR-A1921 injection and adebrelimab injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NSCLC

    phase 2 small molecule active

    1 trial

  41. SHR20004

    Jian Li

    Obesity

    phase 2 small molecule active

    1 trial

  42. SHR2554/AZA + Overlapped TBF

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 2 other active

    1 trial

  43. SI-B001

    Sichuan Baili Pharmaceutical Co.,

    Non Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  44. SIKLOS PAEDIATRIC 50mg dispersible tablets

    THERAVIA

    Sickle Cell Disease

    phase 2 small molecule active

    1 trial

  45. SILIMARIN 200 mg compresse rivestite, Kisqali 200 mg film-coated tablets

    Fondazione Telethon ETS

    hormone receptor positive, HER2-negative breast cancer

    phase 2 small molecule active

    1 trial

  46. SILTUXIMAB , PREDNISOLONE , CYCLOPHOSPHAMIDE , CARBOPLATIN , PARACETAMOL , ETOPOSIDE , VINCRISTINE , LENALIDOMIDE , DIPHENHYDRAMINE , GEMCITABINE , PREDNISONE , OXALIPLATIN , TOCILIZUMAB , Epcoritamab, Epcoritamab, DEXAMETHASONE , DOXORUBICIN , CYTARABINE , RITUXIMAB , IFOSFAMIDE , ANAKINRA , BENDAMUSTINE

    Genmab A/S

    Lymphoma of B-cell origin

    phase 2 small molecule active

    1 trial

  47. SILTUXIMAB, Tarlatamab, Tarlatamab

    Amgen

    Small Cell Lung Cancer (SCLC)

    phase 2 small molecule active

    1 trial

  48. SION-719

    Sionna Therapeutics

    Cystic Fibrosis (CF)

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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