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Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. SIROLIMUS

    Pari Pharma GmbH

    Adult patients (men and women) (≥ 18 years of age) with cutaneous sarcoidosis involving the face

    phase 2 small molecule active

    1 trial

  2. SIROLIMUS, BEKEMV 300 mg concentrate for solution for infusion, SIROLIMUS, PREDNISONE, METHYLPREDNISOLONE SODIUM SUCCINATE, PARACETAMOL, Epysqli 300 mg concentrate for solution for infusion, PREDNISONE, DIPHENHYDRAMINE HYDROCHLORIDE, SIROLIMUS, PREDNISONE, RITUXIMAB, RITUXIMAB, ECULIZUMAB, BEKEMV 300 mg concentrate for solution for infusion, AAV9.LAMP2B, DIPHENHYDRAMINE HYDROCHLORIDE, PARACETAMOL, METHYLPREDNISOLONE SODIUM SUCCINATE, PREDNISONE, SIROLIMUS, BEKEMV 300 mg concentrate for solution for infusion

    Lacuna Pharma Pty Ltd

    Danon Disease

    phase 2 small molecule active

    1 trial

  3. SIROLIMUS, SIROLIMUS

    Lacuna Pharma Pty Ltd

    Subjects diagnosed with port wine stains

    phase 2 small molecule active

    1 trial

  4. SIRT Yttrium-90

    Chinese University of Hong Kong

    Cholangio Carcinoma

    phase 2 small molecule completed

    1 trial

  5. SK-PC-B70M

    Chemical Works of Gedeon Richter Plc. (Gedeon Richter Plc.)

    Alzheimer's Disease

    phase 2 small molecule completed

    1 trial

  6. SKB103 for injection monotherapy

    Sichuan Provincial People's Hospital

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  7. SKY0402

    Pacira Ireland Limited

    Inguinal Hernia

    phase 2 small molecule completed

    1 trial

  8. SKY0402

    Pacira Ireland Limited

    Postoperative Pain

    phase 2 small molecule completed

    3 trials

  9. SKY0402 + bupivacaine HCl

    Pacira Ireland Limited

    Postoperative Pain

    phase 2 small molecule completed

    1 trial

  10. SL-BUP

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Use Disorder (OUD)

    phase 2 small molecule active

    1 trial

  11. SLN124

    Silence Therapeutics plc

    Polycythemia Vera

    phase 2 small molecule active

    1 trial

  12. SLN360

    Silence Therapeutics plc

    Cardiovascular Diseases

    phase 2 small molecule completed

    1 trial

  13. SM101

    Takeda

    Immunoglobulin A Nephropathy

    phase 2 mab terminated

    1 trial

  14. SMT19969

    Summit Therapeutics

    Clostridium Difficile Infection

    phase 2 small molecule completed

    1 trial

  15. SNA02-48

    Sinovac Research and Development Co.,

    Tetanus

    phase 2 mab active

    1 trial

  16. SNDX-5613

    Syndax Pharmaceuticals

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial

  17. SNDX-6352

    Syndax Pharmaceuticals

    Coronavirus

    phase 2 small molecule terminated

    1 trial

  18. SNS-101 (anti-VISTA)

    Regeneron UK Limited

    Solid Tumor, Adult

    phase 2 small molecule active

    1 trial

  19. SNS-301

    Sensei Biotherapeutics

    Squamous Cell Carcinoma of the Head and Neck

    phase 2 small molecule terminated

    1 trial

  20. SNS-301

    Sensei Biotherapeutics

    Myelodysplastic Syndromes

    phase 2 small molecule terminated

    1 trial

  21. SNUBH-NM-333(18F)

    Hospital Authority, Hong Kong

    Alzheimer Disease

    phase 2 other terminated

    1 trial

  22. SODIUM CHLORIDE

    Lacuna Pharma Pty Ltd

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial

  23. SODIUM CHLORIDE , DII235

    Novartis Pharmaceuticals

    Cardiovascular risk reduction in participants with elevated Lp(a)

    phase 2 small molecule active

    1 trial

  24. SODIUM CHLORIDE SOLUTION 0.9%

    Lacuna Pharma Pty Ltd

    Acute Ischemic Stroke

    phase 2 small molecule active

    1 trial

  25. SODIUM CHLORIDE SOLUTION 0.9%, mRNA-1345

    Moderna Biotech Spain

    Respiratory syncytial virus

    phase 2 small molecule active

    1 trial

  26. SODIUM CHLORIDE, ADALIMUMAB, LAD191, LAD191 placebo

    Almirall, S.A.

    Moderate-to-severe hidradenitis suppurativa

    phase 2 small molecule active

    1 trial

  27. SODIUM CHLORIDE, ARO-DUX4

    Sarepta Therapeutics

    Facioscapulohumeral muscular dystrophy (FSHD)

    phase 2 small molecule active

    1 trial

  28. SODIUM CHLORIDE, ENTR-601-45

    Entrada Therapeutics

    Duchenne Muscular Dystrophy

    phase 2 small molecule active

    1 trial

  29. SODIUM CHLORIDE, LIDOCAINE HYDROCHLORIDE MONOHYDRATE

    The George Institute

    Colon cancer

    phase 2 small molecule active

    1 trial

  30. SODIUM CHLORIDE, MYDRIASERT, insert ophtalmique, 0.34 % tropicamide/ 2.5 % phenylephrine hydrochloride

    Lacuna Pharma Pty Ltd

    to obtain pre-operative mydriasis or for diagnostic purposes

    phase 2 small molecule active

    1 trial

  31. SODIUM LAURILSULFATE, Canoderm 5 % kräm, Aqua ad iniectabilia Braun Lösungsmittel zur Herstellung von Parenteralia, Propyless 200 mg/g kutan emulsion, Miniderm 20 % kräm, CARBAMIDE, COMBINATIONS

    Nordic Bioscience A/S

    Atopic dermatitis

    phase 2 small molecule active

    1 trial

  32. SOF

    Gilead Sciences Ireland UC

    Hepatitis C Virus Infection

    phase 2 small molecule completed

    1 trial

  33. SOF

    Gilead Sciences Ireland UC

    HCV Infection

    phase 2 small molecule completed

    1 trial

  34. SOLDESAM 0,2% gocce orali, soluzione, DARZALEX 1800 mg solution for injection, Imnovid 3 mg hard capsules, SOLDESAM 8 mg/2 ml soluzione iniettabile, Imnovid 4 mg hard capsules, Imnovid 1 mg hard capsules, Imnovid 2 mg hard capsules

    Fondazione Telethon ETS

    Multiple Myeloma relapsed and/or refractory

    phase 2 small molecule active

    1 trial

  35. SOLDESAM 0,2% gocce orali, soluzione, Pepaxti 20 mg powder for concentrate for solution for infusion, SOLDESAM 8 mg/2 ml soluzione iniettabile

    Fondazione Telethon ETS

    Relapsed Multiple Myeloma

    phase 2 small molecule active

    1 trial

  36. SOTATERCEPT, SOTATERCEPT, sotatercept, sotatercept

    Merck Sharp and Dohme

    Pulmonary Hypertension

    phase 2 small molecule active

    1 trial

  37. SOTATERCEPT, sotatercept

    Merck Sharp and Dohme

    Pulmonary arterial hypertension

    phase 2 small molecule active

    1 trial

  38. SOTATERCEPT, sotatercept, sotatercept, SOTATERCEPT

    Merck Sharp and Dohme

    Pulmonary Arterial Hypertension (PAH)

    phase 2 small molecule active

    1 trial

  39. SOTORASIB

    Amgen

    KRAS p.G12C Mutant Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  40. SOTORASIB

    Amgen

    Non-small cell lung cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  41. SOX Chemotherapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Gastroesophageal Junction Adenocarcinoma

    phase 2 small molecule active

    1 trial

  42. SPD476 is a polymeric matrix formulation that displays both delayed- and extended-release of mesalazine

    Takeda

    Colitis, Ulcerative

    phase 2 small molecule completed

    1 trial

  43. SPD489 (lisdexamfetamine dimesylate)

    Takeda

    Schizophrenia and Predominant Negative Symptoms

    phase 2 small molecule completed

    1 trial

  44. SPD489 20 mg

    Takeda

    Sleep Deprivation

    phase 2 small molecule completed

    1 trial

  45. SPD503 (Guanfacine HCl)

    Takeda

    Attention Deficit Disorder With Hyperactivity

    phase 2 small molecule completed

    1 trial

  46. SPD503 (extended-release Guanfacine hydrochloride)

    Takeda

    Generalized Anxiety Disorder (GAD)

    phase 2 small molecule completed

    1 trial

  47. SPD557

    Takeda

    Gastroesophageal Reflux Disease

    phase 2 small molecule terminated

    1 trial

  48. SPD602

    Takeda

    Iron Overload Due to Repeated Red Blood Cell Transfusions

    phase 2 small molecule terminated

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

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