Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 103 of 151

  1. Phase 1b: APG-115+pembrolizumab

    Ascentage Pharma Group

    Unresectable or Metastatic Melanoma or Advanced Solid Tumors

    phase 2 small molecule active

    1 trial

  2. Phase I Study of PM534 Administered to Patients with Advanced Solid Tumors

    Lacuna Pharma Pty Ltd

    Advanced Solid Tumors

    phase 2 other active

    1 trial

  3. Phase I Study of PM534 to Patients with Advanced Solid Tumors

    Lacuna Pharma Pty Ltd

    Advances solid tumors

    phase 2 other active

    1 trial

  4. Phenoptin

    BioMarin Pharmaceutical Australia Pty Ltd

    Tetrahydrobiopterin Deficiencies

    phase 2 small molecule completed

    1 trial

  5. Phosphate buffered saline for SC administration

    Alnylam Netherlands B.V.

    Type 2 Diabetes Mellitus

    phase 2 small molecule active

    1 trial

  6. Piclidenoson

    Can-Fite BioPharma

    COVID-19

    phase 2 small molecule completed

    1 trial

  7. Piclidenoson

    Can-Fite BioPharma

    Lowe Syndrome

    phase 2 small molecule active

    1 trial

  8. Pimavanserin

    Acadia Pharmaceuticals B.V.

    Agitation and Aggression in Alzheimer's Disease

    phase 2 small molecule completed

    1 trial

  9. Pimavanserin

    Acadia Pharmaceuticals B.V.

    Parkinson's Disease

    phase 2 small molecule terminated

    1 trial

  10. Pimavanserin

    Acadia Pharmaceuticals B.V.

    Treatment of Depression in Adults With Parkinson's Disease (PD)

    phase 2 small molecule completed

    1 trial

  11. Pimavanserin 34 mg

    Acadia Pharmaceuticals B.V.

    Intermittent Explosive Disorder

    phase 2 small molecule active

    1 trial

  12. Pimavanserin 34 mg

    Acadia Pharmaceuticals B.V.

    Agitation and Aggression in Alzheimer's Disease

    phase 2 small molecule terminated

    1 trial

  13. Pimavanserin 34 milligrams (MG) [Nuplazid]

    Acadia Pharmaceuticals B.V.

    Schizophrenia

    phase 2 small molecule terminated

    1 trial

  14. Pimavanserin Tartrate 34 Mg ORAL CAPSULE [NUPLAZID]

    Acadia Pharmaceuticals B.V.

    Autism Spectrum Disorder

    phase 2 small molecule active

    1 trial

  15. Pimavanserin tartrate

    Acadia Pharmaceuticals B.V.

    Alzheimer's Disease Psychosis

    phase 2 small molecule completed

    1 trial

  16. Pioglitazone

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorder

    phase 2 small molecule completed

    1 trial

  17. Pioglitazone

    Takeda

    Oxidative Stress

    phase 2 small molecule completed

    1 trial

  18. Pioglitazone

    Takeda

    Inflammation

    phase 2 small molecule completed

    1 trial

  19. Pioglitazone

    Takeda

    Depressive Disorder, Major

    phase 2 small molecule completed

    1 trial

  20. Pioglitazone

    Takeda

    Chronic Pancreatitis

    phase 2 small molecule completed

    1 trial

  21. Pioglitazone and atorvastatin

    Takeda

    Cardiovascular Diseases

    phase 2 small molecule completed

    1 trial

  22. Pioglitazone and azilsartan

    Takeda

    Diabetes Mellitus

    phase 2 small molecule completed

    1 trial

  23. Piqray 50 mg and 200 mg film-coated tablets

    Wuhan Createrna Science and Technology Co., Ltd

    metasatic breast cancer, hormon positive, her 2 negative

    phase 2 small molecule active

    1 trial

  24. Pirarubicin

    The First People's Hospital of Lianyungang

    Upper Tract Urothelial Carcinoma

    phase 2 small molecule active

    1 trial

  25. Pirfenidone

    United Therapeutics Europe Ltd

    Cardiac Failure

    phase 2 small molecule completed

    1 trial

  26. Pirfenidone Solution for Inhalation

    Lacuna Pharma Pty Ltd

    Interstitial Lung Diseases (ILD), including but not limited to idiopathic pulmonary fibrosis (IPF)

    phase 2 small molecule active

    1 trial

  27. Pirfenidone Solution for Inhalation

    Lacuna Pharma Pty Ltd

    Progressive pulmonary fibrosis [PPF] Idiopathic pulmonary fibrosis [IPF]

    phase 2 small molecule active

    1 trial

  28. Piromelatine (Neu-P11)

    Lacuna Pharma Pty Ltd

    idiopathic (isolated) Rapid Eye Movement Behavior Disorder

    phase 2 small molecule active

    1 trial

  29. Pirtobrutinib, Placebo tablets

    Eli Lilly Co.

    Immune Thrombocytopenia

    phase 2 small molecule active

    1 trial

  30. Pitolisant Oral Tablet

    Harmony Biosciences Holdings

    Myotonic Dystrophy 1

    phase 2 small molecule completed

    1 trial

  31. Pitolisant oral tablets

    Harmony Biosciences Holdings

    Prader-Willi Syndrome

    phase 2 small molecule completed

    1 trial

  32. Placebo

    Cardiff Oncology

    Metastatic Breast Cancer

    phase 2 small molecule terminated

    1 trial

  33. Placebo

    PTC THERAPEUTICS, INC.

    Friedreich's Ataxia

    phase 2 small molecule completed

    1 trial

  34. Placebo

    PTC THERAPEUTICS, INC.

    Leigh Syndrome

    phase 2 small molecule completed

    1 trial

  35. Placebo

    IONIS PHARMACEUTICALS INC

    Mild Hypertension

    phase 2 small molecule completed

    1 trial

  36. Placebo

    IONIS PHARMACEUTICALS INC

    Hypertension

    phase 2 small molecule completed

    2 trials

  37. Placebo

    Jazz Pharmaceuticals Ireland Limited

    Viruria

    phase 2 small molecule completed

    1 trial

  38. Placebo

    Jazz Pharmaceuticals Ireland Limited

    Parkinson Disease

    phase 2 small molecule completed

    1 trial

  39. Placebo

    NEUROCRINE BIOSCIENCES INC

    Major Depressive Disorder

    phase 2 small molecule completed

    1 trial

  40. Placebo

    Viking Therapeutics

    Weight Loss

    phase 2 small molecule completed

    1 trial

  41. Placebo

    NEUROCRINE BIOSCIENCES INC

    Anhedonia

    phase 2 small molecule completed

    1 trial

  42. Placebo

    RIGEL PHARMACEUTICALS INC

    Acute Respiratory Distress Syndrome

    phase 2 small molecule active

    1 trial

  43. Placebo

    Biocryst

    Paroxysmal Nocturnal Hemoglobinuria (PNH)

    phase 2 small molecule terminated

    1 trial

  44. Placebo

    Biocryst

    Gout

    phase 2 small molecule completed

    3 trials

  45. Placebo

    Alnylam Netherlands B.V.

    Cerebral Amyloid Angiopathy

    phase 2 small molecule active

    1 trial

  46. Placebo

    Alnylam Netherlands B.V.

    IgA Nephropathy (IgAN)

    phase 2 small molecule terminated

    1 trial

  47. Placebo

    IONIS PHARMACEUTICALS INC

    NAFLD

    phase 2 small molecule completed

    1 trial

  48. Placebo

    IRONWOOD PHARMACEUTICALS INC

    Functional Constipation in Children Ages 6-17 Years

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.