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Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 12036194

    Methods of administering solriamfetol to lactating women

    AXSOME MALTA LTD. · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 12036269

    Human-enzyme mediated depletion of homocysteine for treating patients with hyperhomocysteinemia and homocystinuria

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 12036319

    Polyvalent sting activating compositions and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 12036231

    Cyclic dinucleotides as agonists of stimulator of interferon gene dependent signalling

    The Board of Regents of the University of Texas System · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 12036314

    Compositions and methods for in situ-forming tissue constructs

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 12036266

    Activatable cytokine polypeptides and methods of use thereof

    Werewolf Therapeutics, Inc. · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 12036205

    Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and cognitive disorders

    Amazentis SA · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 12037401

    Anti-TrkB monoclonal antibodies and methods of use

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 11 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. WO 2024149832

    SARNA (VRP) MODIFIÉ RECOMBINANT POUR VACCIN CONTRE LE CANCER

    BAVARIAN NORDIC AS [DK] · Granted Thu Jul 18 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jul 13 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 12043843

    Materials and methods for treatment of hemoglobinopathies

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 12042479

    Use of topical formulations of cannabinoids in the treatment of epidermolysis bullosa and related connective tissue disorders

    INMED PHARMACEUTICALS INC. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 12042558

    Method and formulation for improving roflumilast skin penetration lag time

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 12042543

    Substituted 3-amino-5-phenylbenzamide compounds as covalent inhibitors of enhancer zeste homolog 2 (EZH2) and proteolysis-targeting chimeric derivatives thereof (PROTACs) that induce degradation of EZH2

    Northwestern University · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 12043847

    Compositions and methods for treating acne

    The Regents of the University of California · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 12042541

    Lipids and compositions for the delivery of therapeutics

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 12043833

    Targeted compositions

    ARBUTUS BIOPHARMA CORPORATION · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 12043667

    CLEC12a binding polypeptides and uses thereof

    Inhibrx Biosciences, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 12042529

    Optimization of enzyme replacement therapy for treatment of homocystinuria

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 12042487

    Method for reducing side effects from administration of phosphodiesterase-4 inhibitors

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 12042510

    Modulators of IRF4 expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 12042538

    Methods of reducing particle formation and compositions formed thereby

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 12042554

    Compositions and methods for blocking ultraviolet radiation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 12043601

    N-substituted-1H-1,2,4-triazole-3-carboxamides, analogues thereof, and methods of treatment using same

    The Regents of the University of Colorado · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 12043607

    HDAC inhibitors and therapeutic use thereof

    Tango Therapeutics, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 12043831

    Modulation of alpha synuclein expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 12043610

    Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors

    BioCryst Pharmaceuticals, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 12043629

    RIP1K inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 12043640

    Prodrugs of STAT3 inhibitors

    Tvardi Therapeutics, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 12043620

    Benzazole compounds and methods for making and using the compounds

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 12043650

    Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulator (CFTR) gene

    Sangamo Therapeutics, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 12043655

    Constitutively active chimeric cytokine receptors

    Allogene Therapeutics, Inc. · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 12043660

    10E8 neutralizing antibody variants that bind to the MPER region of HIV-1 GP41 and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 23 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 18 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. CN 118401500

    Process for preparing mixtures of dimeric macrocyclic intermediates comprising gadolinium complexes

    BRACCO IMAGING SPA · Granted Fri Jul 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Jul 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. NZ 743471

    Improved immunoglobulin variable domains

    ABLYNX NV · Granted Fri Jul 26 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Jul 21 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 12048317

    Astaxanthin-containing condiment and a preparation method therefor

    South China University of Technology · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 12049471

    Cyano cyclobutyl compounds for Cbl-b inhibition and uses thereof

    NURIX THERAPEUTICS, INC. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 12049479

    Foot and mouth disease virus (FMDV) consensus proteins, coding sequences therefor and vaccines made therefrom

    Inovio Pharmaceuticals, Inc. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 12048749

    C40-, C28-, and C-32-linked rapamycin analogs as mTOR inhibitors

    Revolution Medicines, Inc. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 12049487

    Universal chimeric antigen receptor T-cell preparation technique

    GRACELL BIOTECHNOLOGIES (SHANGHAI) CO., LTD. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 12048710

    Compositions and methods for modification of biomolecules

    The Regents of the University of California · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 12049486

    PAC1 receptor agonists (MAXCAPs) and uses thereof

    The United States Government represented by the Department of Veterans Affairs · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 12049644

    Platform for generating safe cell therapeutics

    The Regents of the University of California · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 12050227

    Lipid nanodisc formation by acryloyl-based copolymers

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 12049670

    Proprotein convertase subtilisin/kexin type 1 (PCSK1) variants and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 12049630

    Factor XII (F12) iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 12049628

    Transthyretin (TTR) iRNA compositions and methods of use thereof for treating or preventing TTR-associated diseases

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 12049652

    PH20 polypeptide variants, formulations and uses thereof

    HALOZYME, INC. · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 12049645

    Differentiation of pancreatic endocrine cells

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 25 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.

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