Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 12053519

    HIV-1 Env fusion peptide nanoparticle carrier conjugates and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 06 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12053481

    Compositions and methods for deep dermal drug delivery

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue Aug 06 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12055553

    Method for diagnosing risk for inflammatory disease through glycan profiling

    The Regents of the University of California · Granted Tue Aug 06 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12053534

    Radiolabeled anti-PD-L1 antibodies for immuno-PET imaging

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 06 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 01 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. WO 2024162304

    LIPIDE CARBAMOYLE OU LIPIDE D'URÉE AYANT CHACUN UNE AMINE CYCLIQUE, NANOPARTICULES LIPIDIQUES LE CONTENANT ET COMPOSITION PHARMACEUTIQUE

    ASTELLAS PHARMA INC [JP] · Granted Thu Aug 08 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 03 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12060555

    MicroRNA-33 inhibitors and use thereof in the treatment of pulmonary fibrosis

    UNIVERSITY OF CONNECTICUT · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12060566

    Self-inactivating lentiviral vector comprising a FOXP3 expression cassette

    The Regents of the University of California · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 12061206

    Diagnosis and treatment of autoimmune diseases

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 12060590

    PH20 polypeptide variants, formulations and uses thereof

    HALOZYME, INC. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 12059214

    System and method of performing treatment along a lumen network

    Covidien LP · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 12060327

    Psychotropic agents and uses thereof

    LB PHARMACEUTICALS INC. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 12059471

    Complex

    UNITED IMMUNITY, CO., LTD. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 12060346

    Inhibitors of APOL1 and methods of using same

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 12059474

    Methods for selecting antibodies that specifically bind glycosylated immune checkpoint proteins

    The Board of Regents of the University of Texas System · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 12059413

    Methods of inhibiting viruses using compositions targeting TSG101-ubiquitin interaction

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 12059477

    Nanomaterials

    Beam Therapeutics Inc. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 12060398

    Fibrous proteinaceous networks and methods of use thereof

    Northwestern University · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 12059443

    Method for treating cancer using dengue virus serotype 1 (DENV-1)

    PrimeVax Immuno-Oncology · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 12059468

    Carbohydrate conjugates as delivery agents for oligonucleotides

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12059400

    Medical compound

    VERA SALUS RICERCA S.R.L. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 12060350

    Therapeutic compounds and methods of use thereof

    Regents of the University of Minnesota · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 12060497

    Coatings containing polymer modified enzyme for stable self-cleaning of organic stains

    Regents of the University of Minnesota · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 12060396

    Fused in sarcoma (FUS) nuclear translocation inhibitors for preventing fibrosis

    THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 12059437

    Methods and compositions for hematopoietic stem cell mobilization

    The Regents of the University of California · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 12060428

    Anti-IL36R antibodies

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 12060362

    Inhibitors of glucose transporters (GLUTs)

    Lead Discovery Center GmbH · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 12059407

    Compositions and methods for delivery of macromolecules

    The Regents of the University of California · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 12060419

    CD79A chimeric antigen receptors

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 12060558

    Methods and compositions for treatment of cholesteryl ester storage disease

    STOKE THERAPEUTICS, INC. · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 12059418

    Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 12060382

    Crystalline phases of 5,6-dichloro-2-(isopropylamino)-(1 β-L-ribofuranosyl)-1H-benzimidazole

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 13 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 08 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. UY 40647

    DERIVADOS DE ETILSULFONA/SULFOXIMINA-PIRIDINA SUSTITUIDOS CON TETRAZOL

    BOEHRINGER INGELHEIM VETMEDICA GMBH [DE] · Granted Thu Aug 15 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. UY 40645

    DERIVADOS DE ETIL-SULFOXIMA-PIRIDINA SUSTITUIDOS CON CICLOPROPIL-(HETERO)ARILO

    BOEHRINGER INGELHEIM VETMEDICA GMBH [DE] · Granted Thu Aug 15 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. UY 40646

    DERIVADOS DE N-ÓXIDO DE ETIL-SULFONA/SULFOXIMINA-PIRIDINA SUSTITUIDOS CON CICLOPROPIL-(HETERO)ARILO

    BOEHRINGER INGELHEIM VETMEDICA GMBH [DE] · Granted Thu Aug 15 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 10 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 12064507

    Composition and method for oral treatment of leukemia

    Provectus Pharmatech, Inc. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 12064512

    Silyl lipids suitable for enhanced delivery of anti-viral therapeutics

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 12064488

    Nitroxide containing amyloid binding agents for imaging and therapeutic uses

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 12064399

    Use of cannabinoids in the treatment of epilepsy

    JAZZ PHARMACEUTICALS RESEARCH UK LIMITED · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 12065432

    Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid

    Vertex Pharmaceuticals Incorporated · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 12066246

    Target residual moisture content for lyophilized drug product

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 12065458

    Trialkyne linking agents and methods of use

    Arrowhead Pharmaceuticals, Inc. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 12064514

    Ultrasound-sensitive peptide particles for spatially resolved molecule delivery

    THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 12064502

    Peptide exhibiting wrinkle-improving activity and uses thereof

    CAREGEN CO., LTD. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 12064413

    Methods of treating melanoma with S-equol

    The Board of Regents of the University of Texas System · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 12064398

    Parenteral formulations

    JAZZ PHARMACEUTICALS RESEARCH UK LIMITED · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 12064453

    Biochemical and biomechanical conditioning for enhancing personalized mesenchymal stem cell therapies

    The Board of Regents of the University of Texas System · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 12068729

    Anti-factor XII/XIIa antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 12065506

    Anti-TMPRSS2 antibodies and antigen-binding fragments

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.