Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2044

Annual patent cliff calendar for 2044 — US pharmaceutical patents by expiration date.

Patents
1,766

Quick answer

1,766 indexed pharmaceutical patents have expiration dates in 2044. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 12064472

    Southern cattle tick vaccine product

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 12064411

    Methods of administering solriamfetol to lactating women

    AXSOME MALTA LTD. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 12064402

    Binge behavior regulators

    CLEARMIND MEDICINE INC. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 12064507

    Composition and method for oral treatment of leukemia

    Provectus Pharmatech, Inc. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 12064511

    Lipid nanoparticles containing silyl lipids for use in vaccines and gene therapy

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 12064476

    Zika virus immunogenic compositions

    Regents of the University of Minnesota · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 12065404

    C4-carboxylic acid-substituted tryptamine derivatives and methods of using

    Enveric Biosciences Canada Inc. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 12065416

    cGAS antagonist compounds

    The Board of Regents of the University of Texas System · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 12065412

    CFTR regulators and methods of use thereof

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 12065485

    Treatment of staphylococcal disorders

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 12065489

    Claudin-6 antibodies and drug conjugates

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 12065448

    Heteroaryl plasma kallikrein inhibitors

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 12065479

    Force sensor cleavage domain containing chimeric polypeptides and methods of use thereof

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 12065493

    Anti-MICA/B antibodies that block MICA/B shedding and methods of use

    Cullinan Mica Corporation · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 12065498

    Methods of making bispecific anti-CD307E and anti-BCMA chimeric antigen receptors and uses of the same

    Cell Design Labs, Inc. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 12065506

    Anti-TMPRSS2 antibodies and antigen-binding fragments

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 12068729

    Anti-factor XII/XIIa antibodies and uses thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 12064512

    Silyl lipids suitable for enhanced delivery of anti-viral therapeutics

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 12064488

    Nitroxide containing amyloid binding agents for imaging and therapeutic uses

    The Regents of the University of California · Granted Tue Aug 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 15 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 12070509

    Nucleic acids and methods of treatment for cystic fibrosis

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 12070444

    Modulation of molecular markers using S-equol

    The Board of Regents of the University of Texas System · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 12071632

    Chimeric vectors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 12071636

    Pasteurella multocida strains and vaccines having hyaC and nanP deletions

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 12070502

    Process for reducing subvisible particles in a pharmaceutical formulation

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 12071619

    SERPINA1 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 12072338

    Pharmaceutical peptides for the treatment of inflammatory diseases

    PROTAGONISTS LTD. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 12071468

    Purification of Factor VIII subspecies

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 12071516

    Polymeric stabilizing formulations

    Nano Precision Medical, Inc. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 12071477

    Anti-folate receptor alpha antibody conjugated with hemiasterlins

    Sutro Biopharma, Inc. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 12070460

    Methods of treating skin cancer with Carboxypeptidase Vitellogenic Like (CPVL) inhibitors

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 12070510

    Injection of single-stranded or self-complementary adeno-associated virus 9 into the cerebrospinal fluid

    REGENXBIO INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 12070594

    Biomedical electrode with anti-microbial properties

    COMPASS HEALTH BRANDS CORP. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 12071436

    Anti-parasitic compounds and uses thereof

    The Regents of the University of California · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 12070495

    HIV RNA vaccines

    The United States of America, as represented by the Department of Health and Human Services · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 12070628

    Low energy immune priming for treating cancer and metastasis

    Montefiore Medical Center · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 12071411

    Inhibitors of HIF-2α and methods of use thereof

    Arcus Biosciences, Inc. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 12071391

    Methods for making and using endoxifen

    ATOSSA THERAPEUTICS, INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 12071438

    Crystal forms of an ALK2 inhibitor

    Keros Therapeutics, Inc. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 12071442

    Substituted pyrrolo[3,4-c]pyridines as HPK1 antagonists

    Nimbus Saturn, Inc. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 12070500

    Use of semaphorin-4D antibodies in combination with an immune modulating therapy to inhibit tumor growth and metastasis

    VACCINEX, INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 12071413

    Azole derivatives as apelin receptor agonist

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 12070506

    Steroids and antibody-conjugates thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 12070472

    Treatment of drug resistant proliferative diseases with telomerase mediated telomere altering compounds

    The Board of Regents of the University of Texas System · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 12071434

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 12071414

    Apelin receptor agonists and methods of use thereof

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 12070443

    Methods of treating and preventing breast cancer with S-equol

    The Board of Regents of the University of Texas System · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 12071428

    Indazole compounds as kinase inhibitors

    TYRA BIOSCIENCES, INC. · Granted Tue Aug 27 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 22 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. WO 2024175803

    COMPOSÉS POUR LE TRAITEMENT DE MALADIES MYÉLOÏDES AVEC DES ANOMALIES CHROMOSOMIQUES

    AB SCIENCE [FR] · Granted Thu Aug 29 2024 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 24 2044 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2044?

1,766 published patents in our USPTO index have expiration dates falling in calendar year 2044.