Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11760794

    Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 11760790

    Neutralizing antibodies to HIV-1 Env and their use

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 11760789

    Broadly neutralizing antibodies against HIV

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 11760740

    Highly purified pharmaceutical grade tasimelteon

    VANDA PHARMACEUTICALS INC. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 11760761

    Methods and compositions for targeting PD-L1

    Aligos Therapeutics, Inc. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 11759526

    Method and molecules

    The Regents of the University of California · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 11760755

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 11759515

    Compositions and methods for inducing immune responses

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 11759522

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 11759482

    Methods and compositions for treating skeletal muscular dystrophy

    Capricor, Inc. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 11759446

    Liquid tasimelteon formulations and methods of use thereof

    VANDA PHARMACEUTICALS INC. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 11759459

    Treatment of pain by subarachnoid administration of sustained-release liposomal anesthetic compositions

    Pacira Pharmaceuticals, Inc. · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. CN 116783219

    T cell recruitment polypeptides based on TCR alpha/beta reactivity

    ABLYNX NV · Granted Tue Sep 19 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 14 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 11767330

    Citrate salt, pharmaceutical compositions, and methods of making and using the same

    FOGHORN THERAPEUTICS INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 11767321

    5- and 6-azaindole compounds for inhibition of BCR-ABL tyrosine kinases

    Enliven Inc. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 11767325

    Substituted [1,2,4]triazolo[4,3-a]pyrazines as ion channel modulators

    PRAXIS PRECISION MEDICINES, INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 11767303

    Compounds and methods for inhibiting viral replication and methods of treating and preventing flaviviral infections

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 11766476

    Genomic deletion in African swine fever vaccine allowing efficient growth in stable cell lines

    The United States of America, as represented by the Secretary of Agriculture · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 11766032

    Genetically modified non-human animals expressing human EPO

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 11766558

    Biomedical electrode with anti-microbial properties

    COMPASS HEALTH BRANDS CORP. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 11766403

    Peptide-targeted liposomal delivery for treatment, diagnosis, and imaging of diseases and disorders

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 11766408

    Compositions and methods for organ specific delivery of nucleic acids

    The Board of Regents of the University of Texas System · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 11766402

    Methods for production of MSC-derived exosomes

    The Board of Regents of the University of Texas System · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 11766432

    Cleavable conjugates of catechol compounds and water-soluble polymers and methods of treatment using the same

    Serina Therapeutics, Inc. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 11769597

    Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 11767500

    Systems for producing cellular immunotherapeutics and methods of use thereof

    Northwestern University · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 11766489

    Adeno-associated virus variant capsids and use for inhibiting angiogenesis

    4D MOLECULAR THERAPEUTICS INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 11766487

    Treatments for retinal disease

    4D MOLECULAR THERAPEUTICS INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 11767334

    Heteroaryl inhibitors of PDE4

    Tetra Discovery Partners · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 11767355

    Methods for modulating an immune response

    Cue Biopharma, Inc. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 11767526

    Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 11767367

    Monoclonal antibody neo-201 for the treatment of human carcinomas

    PRECISION BIOLOGICS, INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 11767358

    Human antibodies to Bet v 1 and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 26 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 21 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. WO 2023183767

    MÉTHODES ET COMPOSITIONS POUR AUGMENTER LA SENSIBILITÉ À L'INSULINE

    ABBOTT LAB [US] · Granted Thu Sep 28 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 23 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 2023302008

    METHODS OF ADMINISTERING INTRAVENOUS MELOXICAM IN A BOLUS DOSE

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Sep 28 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 23 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 11771752

    Composition for oral or nasal delivery of tetanus, diphtheria, and pertussis vaccine alone or in combination using neurotoxin associated proteins

    Prime Bio, Inc. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 11773148

    Tau peptide immunogen constructs

    UNITED NEUROSCIENCE · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 11773138

    Polypeptides including a beta-tricalcium phosphate-binding sequence and uses thereof

    Theradaptive, Inc. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 11773156

    Anti-hemagglutinin antibodies and methods of use thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 11773103

    IRAK4 degraders and uses thereof

    Kymera Therapeutics, Inc. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 11773076

    Crystalline forms of a somatostatin modulator

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 11773110

    Heterocycle amines and uses thereof

    Ligand Pharmaceuticals Incorporated · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 11773085

    Methods and compounds for treating disorders

    FOGHORN THERAPEUTICS INC. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 11773057

    Naphthalenesulfonamide compound, preparation method, and application

    CHINA PHARMACEUTICAL UNIVERSITY · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 11771879

    Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device

    Rani Therapeutics, LLC · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 11773185

    Anti-BACE1 antibodies and methods of use thereof

    DENALI THERAPEUTICS INC. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 11773393

    Treatment of liver diseases with cell death inducing DFFA like effector B (CIDEB) inhibitors

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 11771739

    Methods and compositions for treating microbial inflammation

    THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS · Granted Tue Oct 03 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 28 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.