Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11730775

    Methods for treatment of Clostridium difficile infection or recurrence or symptoms thereof

    Seres Therapeutics, Inc. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11730723

    Compounds and methods for treating viral infections

    LEXICON PHARMACEUTICALS, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11730741

    6-chromanol derivatives for use as a medicament

    Sulfateq B.V. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11730802

    Zika vaccines and immunogenic compositions, and methods of using the same

    Takeda Vaccines, Inc. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11730767

    Methods, apparatuses and systems for instilling stem cells and pharmaceuticals into the human ventricular system

    Regeneration Biomedical, Inc. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11730740

    Laureth-4 containing topical formulations

    ARCUTIS BIOTHERAPEUTICS, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11730178

    Extraction method

    Poly Gain Pte Ltd · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11730794

    Use of a VEGF antagonist to treat angiogenic eye disorders

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11730801

    Live attenuated Zika virus with 3'UTR deletion, vaccine containing and use thereof

    The Board of Regents of the University of Texas System · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11730720

    ALK5 inhibitors

    Theravance Biopharma R&D IP, LLC · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11730717

    Melanin-inspired antimicrobial

    THE BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECHANICAL COLLEGES · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11730709

    Compositions and methods for treating severe pain

    Infirst Healthcare Limited · Granted Tue Aug 22 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 17 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. WO 2023159093

    COMPOSITIONS NUTRITIONNELLES COMPRENANT DES OLIGOSACCHARIDES DE LAIT MATERNEL ET DE L'IMMUNOGLOBULINE BOVINE

    ABBOTT LAB [US] · Granted Thu Aug 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. WO 2023156493

    FORMES CRISTALLINES DE NALTREXONE

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Aug 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. WO 2023158844

    COMPOSITIONS NUTRITIONNELLES EN POUDRE TRAITÉES THERMIQUEMENT ET PROCÉDÉS DE MAINTIEN DE (2S)-HESPÉRIDINE

    ABBOTT LAB [US] · Granted Thu Aug 24 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Aug 19 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11739123

    Process for the preparation of cyclic depsipeptides

    OnKure, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11739294

    Compositions and methods for treating retinal diseases

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11738085

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11739068

    Polymorphs of N-[(3-fluoro-4-methoxypyridin-2-yl)methyl]-3-(methoxymethyl)-1-({4-[(2-oxopyridin-1-yl)methyl]phenyl}methyl)pyrazole-4-carboxamide and salts thereof

    KalVista Pharmaceuticals Limited · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11737983

    Storage stable sincalide formulations

    MAIA PHARMACEUTICALS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11737979

    Method of making lipid-encapsulated RNA nanoparticles

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11737978

    Compositions and methods of using propylene sulfide-based polymers for treatment of Chagas disease

    Northwestern University · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11738035

    Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin

    Compass Pathfinder Limited · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11738053

    Methods and compositions for treating chronic granulomatous disease

    The Board of Regents of the University of Texas System · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11739297

    Method of increasing tumor killing activity of macrophages or monocytes comprising chimeric antigen receptor

    Carisma Therapeutics Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11739152

    Antibodies which bind Fc receptors (FcRn)

    Takeda Pharmaceutical Company Limited · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11739074

    Ras inhibitors

    Revolution Medicines, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11738119

    Antimicrobial catheters

    The Board of Regents of the University of Texas System · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11739101

    Bifunctional degraders of hematopoietic progenitor kinase and therapeutic uses thereof

    NURIX THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11739162

    Side chain modified peptoids useful as structure-stabilizing coatings for biomaterials

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11739309

    CRISPR-Cas12J effector polypeptides and methods of use thereof

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11739345

    Methods of treating phenylketonuria

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11738070

    Methods and compositions for improved cognition

    The Regents of the University of California · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11738015

    Pharmaceutical compositions and methods of using the same

    NODEN PHARMA DESIGNATED ACTIVITY COMPANY · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11737981

    Cellulosic polymer nanoparticles and methods of forming them

    THE TRUSTEES OF PRINCETON UNIVERSITY · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11737993

    Multiple myeloma treatment

    VANDA PHARMACEUTICALS INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11738009

    Bicyclic compounds and their use in the treatment of cancer

    TEMPEST THERAPEUTICS, INC. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11737991

    Eutectic formulations of cyclobenzaprine hydrochloride and amitriptyline hydrochloride

    TONIX PHARMA LIMITED · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11738019

    Substituted heterocycles as antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11738022

    Methods for inducing pupil dilation

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11738050

    Compounds binding to fibroblast activation protein alpha

    Regents of the University of Minnesota · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11738038

    Highly active compounds against COVID-19

    Atea Pharmaceuticals, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11739132

    Separation moieties and methods of use thereof

    Werewolf Therapeutics, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11739133

    T-cell modulatory multimeric polypeptides and methods of use thereof

    Cue Biopharma, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11738116

    Expanded nanofiber structures comprising electrospun nanofibers and a plurality of holes and methods of making and use thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11739063

    DREADD actuators

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11739086

    Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same

    Aclaris Therapeutics, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11739093

    Substituted pyrazolopyrazines, imidazopyrazines and [1,2,4]triazolopyrazines as allosteric SHP2 inhibitors

    Revolution Medicines, Inc. · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.