Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11738035

    Method for treating anxiety disorders, headache disorders, and eating disorders with psilocybin

    Compass Pathfinder Limited · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11737978

    Compositions and methods of using propylene sulfide-based polymers for treatment of Chagas disease

    Northwestern University · Granted Tue Aug 29 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 24 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11746087

    C4-carboxylic acid-substituted tryptamine derivatives and methods of using

    Enveric Biosciences Canada Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11746152

    Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated PD-L1

    The Board of Regents of the University of Texas System · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11746155

    Cannabinoid receptor type 1 (CB1) binding proteins and uses thereof

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11746126

    Bicyclic peptide ligands with detectable moieties and uses thereof

    BicycleRD Limited · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11744892

    Constrained conditionally activated binding proteins

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11744816

    Fixed dose combinations and formulations comprising ETC1002 and ezetimibe and methods of treating or reducing the risk of cardiovascular disease

    Esperion Therapeutics, Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11746077

    2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione for suppressing and treating alpha-synucleinopathies, tauopathies, and other disorders

    PTC THERAPEUTICS, INC. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11744887

    Coronavirus vaccine compositions and methods

    ARCTURUS THERAPEUTICS, INC. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11744885

    Vaccines for recurrent respiratory papillomatosis and methods of using the same

    Inovio Pharmaceuticals, Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11744834

    Metal-porphyrin complexes for the inactivation of the biological activity of opioids

    The Government of the United States of America, as represented by the Secretary of the Navy · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11744831

    Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11744867

    Modulation of microbial synthesis of 4-ethylphenol and 4-ethylphenyl sulfate in behavior and disease

    The Regents of the University of California · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11744812

    Methods of treatment

    First Wave Bio, Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11744828

    Regimens of tafenoquine for prevention of malaria in malaria-naïve subjects

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11746151

    Compositions and methods for treating cancer

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11744837

    Use of cortisol in assessment and prophylactic treatment of hypokalemia associated with glucocorticoid receptor modulator treatment of Cushing's syndrome patients

    Corcept Therapeutics Incorporated · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11744873

    Compositions and methods for the treatment of metabolic and liver disorders

    Viking Therapeutics, Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11744876

    Immunomodulator antibody drug conjugates and uses thereof

    Sutro Biopharma, Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11745026

    Laser assisted wound healing protocol and system

    THE BIOREGENTECH INSTITUTE, INC. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11744893

    Constrained conditionally activated binding proteins

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11745179

    Microfluidic systems and methods for lipoplex-mediated cell transfection

    The Regents of the University of California · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11744898

    Multi-arm polymer conjugates of TLR agonist compounds and related immunotherapeutic treatment methods

    Nektar Therapeutics · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11746102

    Polymorphs of selinexor

    Karyopharm Therapeutics Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11746109

    Crystalline forms of 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one hemihydrate

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11746120

    Stat degraders and uses thereof

    Kymera Therapeutics, Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11746124

    Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates

    Ludwig-Maximilians-Universitat Munchen · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11746335

    Development of dengue virus vaccine components

    The Government of the United States of American, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11749394

    Method and apparatus for providing a pharmacokinetic drug dosing regimen

    Takeda Pharmaceutical Company Limited · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11744790

    Compositions and methods for blocking ultraviolet radiation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11744800

    Methods of use of emulsion formulations of an NK-1 receptor antagonist

    Heron Therapeutics, Inc. · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11744926

    Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications

    The Board of Regents of the University of Texas System · Granted Tue Sep 05 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Aug 31 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. CA 3245150

    COMBINAISONS AVEC UN ANTICORPS ANTI-CD39 HUMAIN, UN ANTICORPS ANTI-PD-1 HUMAIN ET UNE CHIMIOTHÉRAPIE CONTRE LE CANCER GASTRIQUE

    TRISHULA THERAPEUTICS INC [US] · Granted Thu Sep 07 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Sep 02 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11752214

    Protein-antiviral compound conjugates

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11753369

    Creatine prodrugs, compositions and methods of use thereof

    Ultragenyx Pharmaceutical Inc. · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11753377

    Crystal form of 2-methyl-2-propanol and amino-substituted aryl compound

    ZHUHAI UNITED LABORATORIES CO., LTD. · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11752221

    Brush-arm star polymer imaging agents and uses thereof

    BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11752184

    Bioactive concentrates and uses thereof

    PURPLE MUNDO, INC. · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11753398

    Therapeutic compounds

    C4X Discovery Limited · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11752190

    Modulators of complement activity

    RA PHARMACEUTICALS, INC. · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11753444

    Modulation of structured polypeptide specificity

    BicycleRD Limited · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11752217

    Hydrogel prodrug for treatment

    Viking Scientific, Inc. · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11753655

    Compositions and methods for treatment of neurological disorders

    The Board of Regents of the University of Texas System · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11753627

    Dengue tetravalent vaccine containing a common 30 nucleotide deletion in the 3′-UTR of dengue types 1,2,3, and 4, or antigenic chimeric dengue viruses 1,2,3, and 4

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11753447

    Cyclic peptides, methods of synthesis, and methods of treatment

    The Regents of the University of California · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11753408

    Compounds and method for blocking transmission of malarial parasite

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11752137

    Ophthalmic compositions for treating ocular Demodex using lotilaner formulations

    Tarsus Pharmaceuticals, Inc. · Granted Tue Sep 12 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Sep 07 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.