Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2043

Annual patent cliff calendar for 2043 — US pharmaceutical patents by expiration date.

Patents
1,718

Quick answer

1,718 indexed pharmaceutical patents have expiration dates in 2043. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11638761

    Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy

    Dyne Therapeutics, Inc. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11639504

    Methods and compositions for regulation of transgene expression

    Sangamo Therapeutics, Inc. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11638704

    Bicyclic compounds and their use in the treatment of cancer

    TEMPEST THERAPEUTICS, INC. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11638708

    Method of treatment of aggression

    Supernus Pharmaceuticals, Inc. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11638753

    Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy

    PDS Biotechnology Corporation · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11638747

    WT1 vaccine

    Inovio Pharmaceuticals, Inc. · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 11639359

    Bryoid compositions, methods of making and use thereof

    Aphios Corporation · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 11639364

    Potent sialyltransferase inhibitors

    Stichting Radboud universitair medisch centrum · Granted Tue May 02 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Apr 27 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. WO 2023077094

    TRAITEMENT D'UN TROUBLE DÉPRESSIF MAJEUR

    ABBVIE INC [US] · Granted Thu May 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. WO 2023076144

    MÉTHODES ET COMPOSITIONS DESTINÉES À AMÉLIORER LA PRODUCTION ET LA SÉCRÉTION D'INSULINE

    ABBOTT LAB [US] · Granted Thu May 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. CA 3234495

    POLYTHERAPIE DE COMPLEXE DE RADIONUCLEIDES

    NOVARTIS AG [CH] · Granted Thu May 04 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Apr 29 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11642379

    Hematopoietic stem cell engraftment

    The Regents of the University of California · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11642398

    Factor IX polypeptide formulations

    BIOVERATIV THERAPEUTICS INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11642384

    Compositions and methods for the treatment of Netherton Syndrome

    Krystal Biotech, Inc. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11642354

    Methods and compositions comprising ursolic acid and/or resveratrol for treating diabetes, or cancer

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11642331

    Glucocorticoid receptor modulators to treat pancreatic cancer

    Corcept Therapeutics Incorporated · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11642023

    Hyperspectral imaging for detection of transmissible spongiform encephalopathy

    Regents of the University of Minnesota · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11642366

    Methods for preventing a serious health consequence and/or tissue damage after exposure to ionizing radiation and/or chemotherapy

    GLYCOMIRA THERAPEUTICS, INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11642374

    Intracellular genomic transplant and methods of therapy

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11642364

    Exon skipping oligomer conjugates for muscular dystrophy

    Sarepta Therapeutics, Inc. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11642410

    Targeting microbubbles

    The Regents of the University of California · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11642419

    Compositions and methods for treating cardiovascular related disorders

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11642332

    (2R,4R)-5-(5′-chloro-2′-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid

    Theravance Biopharma R&D IP, LLC · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11642323

    Method for modulating metabolism

    Brightseed, Inc. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11642335

    Chemical synthesis of clopidogrel active metabolites and disulfide conjugate prodrugs

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11643453

    Cell

    AUTOLUS LIMITED · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11643656

    Antisense therapies for treating cancer

    The United States Government represented by the Department of Veterans Affairs · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11643394

    Krüppel-like factor 15 (KLF15) small molecule agonists in kidney disease

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11642390

    Method of treatment with a fusion protein comprising apelin and an anti-APLNR antibody

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11642375

    Intracellular genomic transplant and methods of therapy

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11642401

    Activation of resident memory T cells for cancer immunotherapy

    Regents of the University of Minnesota · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11642319

    Targeted nanogels for urinary bladder therapies

    The Regents of the University of Colorado · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11643438

    Antimicrobial peptides and methods of use

    The Board of Regents of the University of Oklahoma · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11642849

    In vivo live 3D printing of regenerative bone healing scaffolds for rapid fracture healing

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11643388

    Inhibitors of alpha 2 beta 1 integrin and methods of use thereof

    The Regents of the University of California · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11643640

    Rift valley fever vaccine

    The Board of Regents of the University of Texas System · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11642339

    Methods of treating symptoms of gastroparesis using velusetrag

    Theravance Biopharma R&D IP, LLC · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11643446

    Progranulin variants

    DENALI THERAPEUTICS INC. · Granted Tue May 09 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 04 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11649454

    Single-stranded RNA-editing oligonucleotides

    ProQR Therapeutics II B.V. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11649239

    Crystal form a of (5-amino-8-(2-methyl-6-(trifluoromethyl)pyridin-4-yl)-7-phenyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)methanol (compound 1)

    Medshine Discovery Inc. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11648307

    Anti-DC-HIL antibodies for cancer diagnosis, prognosis and therapy

    The Board of Regents of the University of Texas System · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11649209

    Crystalline freebase forms of a biphenyl compound

    Theravance Biopharma R&D IP, LLC · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11649207

    Formulations of T-type calcium channel modulators and methods of use thereof

    PRAXIS PRECISION MEDICINES, INC. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11648302

    Indoleamine 2,3-dioxygenase based immunotherapy

    IO Biotech ApS · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11648209

    Compositions and methods for organ specific delivery of nucleic acids

    The Board of Regents of the University of Texas System · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11647776

    Extract, consumable product and method for enriching bioactive metabolite in an extract

    Brightseed, Inc. · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11649237

    Substituted imidazo[1,5-a]pyrazines for IRE1 inhibition

    The Regents of the University of California · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11649438

    Methods and compositions for treating cancer

    CRISPR THERAPEUTICS AG · Granted Tue May 16 2023 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 11 2043 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2043?

1,718 published patents in our USPTO index have expiration dates falling in calendar year 2043.