Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2042

Annual patent cliff calendar for 2042 — US pharmaceutical patents by expiration date.

Patents
1,738

Quick answer

1,738 indexed pharmaceutical patents have expiration dates in 2042. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 11338033

    Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 24 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 19 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 11339112

    Compositions and methods comprising resveratrol

    Biocogent, LLC · Granted Tue May 24 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 19 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 11338119

    Implantable drug delivery devices for localized drug delivery

    The Regents of the University of California · Granted Tue May 24 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 19 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 11338028

    Cancer vaccines targeting LEMD1 and uses thereof

    Inovio Pharmaceuticals, Inc. · Granted Tue May 24 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 19 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 11338026

    Identification of immunologically protective neo-epitopes for the treatment of cancers

    UNIVERSITY OF CONNECTICUT · Granted Tue May 24 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 19 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 11338013

    Combination therapy for C3 inhibition

    Apellis Pharmaceuticals, Inc. · Granted Tue May 24 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 19 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. CA 3198740

    METHODES DE TRAITEMENT D'UN REJET A MEDIATION PAR ANTICORPS

    CSL BEHRING GMBH [DE] · Granted Fri May 27 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu May 22 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. CA 3198544

    PROCEDES D'AUGMENTATION DE LA TAILLE ET DE PROMOTION DE LA CROISSANCE OSSEUSE LINEAIRE

    ABBOTT LAB [US] · Granted Fri May 27 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu May 22 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 11345694

    Antibacterial compounds

    DISCUVA LIMITED · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 11345894

    Cellular seeding and co-culture of a three dimensional fibroblast construct

    United States Government as represented by the Department of Veterans Affairs · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 11344615

    Nucleic acids encoding chimeric dengue/Zika viruses optimized for growth and stability in vero cells

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 11344626

    Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use

    Sutro Biopharma, Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 11344580

    Restimulation of cryopreserved tumor infiltrating lymphocytes

    Iovance Biotherapeutics, Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 11345700

    Methods of preparing inhibitors of influenza viruses replication

    Vertex Pharmaceuticals Incorporated · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 11344513

    Dosage forms and methods for enantiomerically enriched or pure bupropion

    AXSOME THERAPEUTICS, INC. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 11344568

    Methods and compositions for administration of iron

    American Regent, Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 11345715

    Biologically active molecules, conjugates thereof, and therapeutic uses

    REGENERON PHARMACEUTICALS, INC. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 11345928

    Modified immunization vectors

    THE ARIZONA BOARD OF REGENTS · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 11345930

    Codon optimized RPGRORF15 genes and uses thereof

    4D MOLECULAR THERAPEUTICS INC. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 11345904

    Targeted therapeutic lysosomal enzyme fusion proteins, associated formulations and uses thereof

    BIOMARIN PHARMACEUTICAL INC. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 11345734

    Chimeric T cell

    AUTOLUS LIMITED · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 11345733

    Colon and pancreas cancer specific antigens and antibodies

    PRECISION BIOLOGICS, INC. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 11345702

    PGDH inhibitors and methods of making and using

    Myoforte Therapeutics, Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 11345705

    Substituted pyrazolo[1,5-a]pyrimidines as apelin receptor agonists

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 11345659

    Pipecolic esters for inhibition of the proteasome

    The Board of Regents of the University of Texas System · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 11344707

    Devices for applying a topical treatment

    THERMA BRIGHT INC · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 11344631

    Promoter for cell-specific gene expression and uses thereof

    Universita' del Piemonte Orientale · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 11345658

    Compounds and compositions comprising the same for treating hypertension or heart failure

    QUANTUM GENOMICS · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 11344652

    Ionic liquids that sterilize and prevent biofilm formation in skin wound healing devices

    Arizona Board of Regents on Behalf of Northern Arizona University · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 11345653

    Compositions and methods for reactivating cholinesterases

    The Government of the United States, as represented by the Secretary of the Army · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 11344605

    Therapeutic use of inhibitors of t cell activation or stimulation

    HUMANITAS MIRASOLE S.P.A. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 11344581

    Restimulation of cryopreserved tumor infiltrating lymphocytes

    Iovance Biotherapeutics, Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 11344618

    HIV envelope glycoprotein immunogens

    ACADEMISCH MEDISCH CENTRUM · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 11344610

    Prevention and reduction of blood loss

    Takeda Pharmaceutical Company Limited · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 11344609

    Compositions and methods for treating hemoglobinopathies

    Beam Therapeutics Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 11344579

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 11344578

    Immune cells expressing engineered antigen receptors

    The Board of Regents of the University of Texas System · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 11344577

    Car+ T cells genetically modified to eliminate expression of T-cell receptor and/or HLA

    The Board of Regents of the University of Texas System · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 11344575

    Vascular calcification prevention and treatment

    Summit Innovation Labs LLC · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 11344569

    Treatment of sleep-wake disorders and neurodegenerative disease comprising modified resistant maltodextrin

    Northwestern University · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 11344559

    PI3KGAMMA inhibitors

    The Regents of the University of California · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 11344538

    Methods for the treatment of myopia

    Lenz Therapeutics, Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 11344514

    Dosage forms and methods for enantiomerically enriched or pure bupropion

    AXSOME THERAPEUTICS, INC. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 11344557

    Corticotropin releasing factor receptor antagonists

    SPRUCE BIOSCIENCES, INC. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 11344555

    Nucleotide analogs

    The Regents of the University of California · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 11344526

    Implantable drug delivery devices for localized drug delivery

    The Regents of the University of California · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 11344491

    Compositions and methods of using the same for decontamination of skin

    The Regents of the University of California · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 11345678

    Benzopyrazole compound used as RHO kinase inhibitor

    Medshine Discovery Inc. · Granted Tue May 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon May 26 2042 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2042?

1,738 published patents in our USPTO index have expiration dates falling in calendar year 2042.