Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2041

Annual patent cliff calendar for 2041 — US pharmaceutical patents by expiration date.

Patents
2,000

Quick answer

2,000 indexed pharmaceutical patents have expiration dates in 2041. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10912746

    Methods and compositions for treating conditions associated with an abnormal inflammatory response

    First Wave Bio, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10912932

    Drug releasing coatings for balloon catheters

    Lutonix, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10913726

    Centrally active and orally bioavailable antidotes for organophosphate exposure and methods for making and using them

    The Regents of the University of California · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10913750

    Tubulin-binding compounds, compositions and uses related thereto

    The Regents of the University of California · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10912933

    Implants for localized drug delivery and methods of use thereof

    The Regents of the University of California · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10912770

    Targeting AMP deaminase 2 for ameliorating craving for sugar and other substances

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10912776

    Methods of treating cancer

    Corvus Pharmaceuticals, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10912754

    Methods and compositions for treating excessive sleepiness

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10912764

    Salinosporamides and methods of use thereof

    The Regents of the University of California · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. US 10912741

    Prevention of liver cancer with safranal-based formulations

    UNITED ARAB EMIRATES UNIVERSITY · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10912931

    Drug releasing coatings for balloon catheters

    Lutonix, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10912779

    Quinazolines and azaquinazolines as dual inhibitors of RAS/RAF/MEK/ERK and PI3K/AKT/PTEN/mTOR pathways

    Asana BioSciences, LLC · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10912792

    Compounds and methods for modulating angiotensinogen expression

    Ionis Pharmaceuticals, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10912751

    Fixed dose combinations and formulations comprising ETC1002 and ezetimibe and methods of treating or reducing the risk of cardiovascular disease

    Esperion Therapeutics, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10913753

    Thienopyridine carboxamides as ubiquitin-specific protease inhibitors

    Valo Early Discovery, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10912767

    Anthracycline prodrugs and methods of making and using the same

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10912834

    Topical formulations based on ionic species for skin treatment

    The Regents of the University of California · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10912846

    Molecular probes for chemiluminescence imaging and in vivo detection of target molecules

    Arizona Board of Regents on Behalf of the University of Arizona · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10913948

    RNA interference in dermal and fibrotic indications

    Phio Pharmaceuticals Corp. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10913798

    Modulators of ROR1-ROR2 binding

    The Regents of the University of California · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10913888

    Nanotube mediation of degradative chemicals for oil-field application

    MOLECULAR REBAR DESIGN, LLC · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10913761

    2,7-dibromospiro[fluorene-9,4′-piperidine] compounds

    Vertex Pharmaceuticals Incorporated · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10913790

    Compositions of, and methods for, alpha-1 anti trypsin Fc fusion molecules

    The Regents of the University of Colorado, a Body Corporate · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10912860

    Controllable self-annealing microgel particles for biomedical applications

    The Regents of the University of California · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10913722

    Compositions and methods of treating retinal disease

    Aldeyra Therapeutics, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10913946

    RNA modulating oligonucleotides with improved characteristics for the treatment of Duchenne and Becker muscular dystrophy

    BIOMARIN TECHNOLOGIES B.V. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10913947

    Antisense oligomers for treatment of conditions and diseases

    STOKE THERAPEUTICS, INC. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10913950

    TMPRSS6 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Feb 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 04 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. AU 2019294474

    Pyridine derivatives substituted by heterocyclic ring and amino group

    BASILEA PHARMACEUTICA INTERNATIONAL AG ALLSCHWIL [CH] · Granted Thu Feb 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 2021038684

    Compositions and Methods for Cancer Immunotherapy

    ALKERMES PHARMA IRELAND LTD [IE] · Granted Thu Feb 11 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Feb 06 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10919869

    Thiazole derivative and applications

    East China University of Science and Technology · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10918668

    Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases

    Sangamo Therapeutics, Inc. · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10918657

    Treatment of spinal cord injury or traumatic brain injury by inhibition of synuclein protein aggregation

    The Board of Regents of the University of Texas System · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10918594

    Controlled-release CNS modulating compositions and methods for the treatment of otic disorders

    The Regents of the University of California · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10918738

    Method of treating type I diabetes using an AAV vector encoding uracortin 2

    The Regents of the University of California · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10918722

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10918732

    Glycoconjugates and methods for their use

    The Board of Regents of the University of Texas System · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10920223

    Serpina1 iRNA compositions and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10918598

    On demand vesicle formation from vesicle precursors suitable for long-term storage

    The Regents of the University of California · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10918648

    Estrogen receptor modulator combinations

    The Regents of the University of California · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10918653

    Bovine milk oligosaccharides

    The Regents of the University of California · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10918673

    Immunoisolation device

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10919877

    Multifunctional inhibitors of MEK/PI3K and mTOR/MEK/PI3K biological pathways and therapeutic methods using the same

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10918691

    Modulators of complement activity

    RA PHARMACEUTICALS, INC. · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10918703

    Fusion proteins for treating inflammatory diseases

    The Regents of the University of California · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10918666

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10920227

    Compositions and methods of treating amyotrophic lateral sclerosis (ALS)

    VOYAGER THERAPEUTICS, INC. · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10919019

    Apparatus for the synthesis of radiopharmaceutical products

    Ion Beam Applications · Granted Tue Feb 16 2021 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Feb 11 2041 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2041?

2,000 published patents in our USPTO index have expiration dates falling in calendar year 2041.