Wednesday, June 10, 2026
🇺🇸 FDA

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. EP 3668502

    MAKROCYCLISCHE MCL-1-INHIBITOREN UND VERFAHREN ZUR VERWENDUNG

    ABBVIE INC [US] · Granted Wed Jun 24 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Tue Jun 19 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  2. US 2020199221

    ANTIBODIES USEFUL IN CANCER DIAGNOSIS

    ASTELLAS PHARMA INC [JP] · Granted Thu Jun 25 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Wed Jun 20 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  3. US 10696651

    Heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  4. US 10696710

    Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway

    The Board of Regents of the University of Texas System · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  5. US 10695293

    Method of preventing or treating radiation-induced dermatitis with extracellular vesicles

    Capricor, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  6. US 10695296

    Formulations, methods, kit, and dosage forms for improved stability of an active pharmaceutical ingredient

    Asana BioSciences, LLC · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  7. US 10695352

    Combination therapy for treating malignancies

    Agios Pharmaceuticals, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  8. US 10695431

    Solid solution compositions and use in cardiovascular disease

    Infirst Healthcare Limited · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  9. US 10696693

    Fused imidazole derivatives as TGF-beta inhibitors

    Rigel Pharmaceuticals, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  10. US 10696713

    Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof

    Enanta Pharmaceuticals, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  11. US 10695414

    Modulation of replicative fitness by deoptimization of synonymous codons

    THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  12. US 10696945

    Methods for treating a brain tissue damage by cultured adult pluripotent olfactory stem cells

    China Medical University · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  13. US 10696724

    Activatable interleukin-2 polypeptides

    Werewolf Therapeutics, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  14. US 10696723

    Activatable interleukin 12 polypeptides

    Werewolf Therapeutics, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  15. US 10696718

    Compstatin analogs for treatment of neuropathic pain

    Apellis Pharmaceuticals, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  16. US 10696656

    Benzimidazole-carboxamide compounds as 5-HT4 receptor agonists

    Theravance Biopharma R&D IP, LLC · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  17. US 10696689

    Somatostatin modulators and uses thereof

    CRINETICS PHARMACEUTICALS, INC. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  18. US 10695435

    Composition comprising a polymeric reagent

    Nektar Therapeutics · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  19. US 10695372

    Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy

    Iovance Biotherapeutics, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  20. US 10696672

    Amino acid compounds and methods of use

    Pliant Therapeutics, Inc. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  21. US 10695432

    Solid solution compositions and use in severe pain

    Infirst Healthcare Limited · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  22. US 10696631

    Chemical conjugates of evans blue derivatives and their use as radiotherapy and imaging agents

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  23. US 10696654

    Therapeutic compounds

    C4X Discovery Limited · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  24. US 10695355

    Methods for pharmacologic treatment of stroke

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  25. US 10695325

    Compounds and methods for treating an epileptic disorder

    The Regents of the University of California · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  26. US 10695429

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  27. US 10695304

    Dosage forms and methods for enantiomerically enriched or pure bupropion

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  28. US 10695308

    Inhalation formulations of treprostinil

    United Therapeutics Corporation · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  29. US 10695279

    Peptide having skin-whitening activity and use thereof

    CAREGEN CO., LTD. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  30. US 10695430

    Pharmaceutical compositions comprising meloxicam

    AXSOME THERAPEUTICS, INC. · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  31. US 10695320

    Compositions comprising urolithin compounds

    Amazentis SA · Granted Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jun 25 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  32. US 10702569

    Compositions and methods for treatment of pain

    Princeton Biotechnology Corporation · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  33. US 10703701

    Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders

    PTC THERAPEUTICS, INC. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  34. US 10703805

    Molecular imprinting of West Nile antibodies with physiological pH matching

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  35. US 10703797

    Gene therapy vectors for treatment of Danon disease

    Rocket Pharmaceuticals, Ltd. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  36. US 10702506

    Small molecule inhibitors of pendrin ion exchange and pharmaceutical compositions

    The Regents of the University of California · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  37. US 10703735

    4-phenyl-coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer

    Lead Discovery Center GmbH · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  38. US 10702468

    Tea massage oil, preparation method therefor and application thereof

    South China University of Technology · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  39. US 10702528

    Hepatitis B antiviral agents

    Enanta Pharmaceuticals, Inc. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  40. US 10703816

    M971 chimeric antigen receptors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  41. US 10704076

    Multi-tiered high through-put screen for compounds effective against bacterial biofilm and compounds effective for inhibiting and eradicating bacterial biofilm

    Government of the United States, as represented by the Secretary of the Air Force · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  42. US 10703746

    Mutant IDH1 inhibitors useful for treating cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  43. US 10703721

    Caffeic acid derivatives and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  44. US 10703698

    Compounds which activate estrogen receptors and compositions and methods of using the same

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  45. US 10702629

    Conditioning harvested fat for re-injection

    Black Tie Medical Inc. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  46. US 10702628

    Hyaluronic acid derivative and neural stem cells for SCI and PNT regeneration

    Anika Therapeutics S.r.l. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  47. US 10702590

    Compositions and methods for treating thyroid disease

    Script Essentials, LLC · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

  48. US 10702543

    Intranuclear protein transduction through a nucleoside salvage pathway

    United States Government as represented by the Department of Veterans Affairs · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.