Wednesday, June 10, 2026

Intelligence · Patents

Patents expiring in 2040

Annual patent cliff calendar for 2040 — US pharmaceutical patents by expiration date.

Patents
1,866

Quick answer

1,866 indexed pharmaceutical patents have expiration dates in 2040. Browse by soonest expiry with links to assignee companies and related drugs.

  1. US 10703721

    Caffeic acid derivatives and uses thereof

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  2. US 10703746

    Mutant IDH1 inhibitors useful for treating cancer

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  3. US 10704076

    Multi-tiered high through-put screen for compounds effective against bacterial biofilm and compounds effective for inhibiting and eradicating bacterial biofilm

    Government of the United States, as represented by the Secretary of the Air Force · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  4. US 10703816

    M971 chimeric antigen receptors

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  5. US 10702506

    Small molecule inhibitors of pendrin ion exchange and pharmaceutical compositions

    The Regents of the University of California · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  6. US 10702569

    Compositions and methods for treatment of pain

    Princeton Biotechnology Corporation · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  7. US 10703701

    Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders

    PTC THERAPEUTICS, INC. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  8. US 10703797

    Gene therapy vectors for treatment of Danon disease

    Rocket Pharmaceuticals, Ltd. · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  9. US 10703805

    Molecular imprinting of West Nile antibodies with physiological pH matching

    The Board of Regents of the University of Texas System · Granted Tue Jul 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 02 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  10. HR P20200591

    ANTIBODIES SPECIFIC FOR CLAUDIN 6 (CLDN6)

    ASTELLAS PHARMA INC [JP] · Granted Fri Jul 10 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Thu Jul 05 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  11. US 10709739

    Method for chemoselection

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  12. US 10709790

    Chemical conjugates of Evans Blue derivatives and their use in the production of long-acting therapeutics

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  13. US 10709799

    Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof

    CytomX Therapeutics, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  14. US 10711257

    Modified cascade ribonucleoproteins and uses thereof

    Caribou Biosciences, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  15. US 10710958

    Carbamoyl phenylalaninol compounds and uses thereof

    Jazz Pharmaceuticals Ireland Limited · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  16. US 10710983

    2,4-diamino-pyrimidine compounds and method for making and using the compounds

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  17. US 10710989

    Method for producing heterocyclic compound

    Takeda Pharmaceutical Company Limited · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  18. US 10709813

    Solubilization of antigen components for removal from tissues

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  19. US 10711007

    Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

    Prelude Therapeutics, Incorporated · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  20. US 10711314

    Methods for diagnosing IDH-mutant cell proliferation disorders

    Agios Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  21. US 10709812

    Biodegradable hydrogel for tissue expansion

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  22. US 10709758

    Peptide inhibitors of clostridium difficile toxin B (TcdB) toxin

    The Board of Regents of the University of Oklahoma · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  23. US 10711032

    Steroids and protein-conjugates thereof

    REGENERON PHARMACEUTICALS, INC. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  24. US 10711292

    Method for promoting the synthesis of collagen and proteoglycan in chondrocytes

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  25. US 10711068

    Anti-CD133 monoclonal antibodies and related compositions and methods

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  26. US 10711312

    Methods for immunotherapy-based treatment and assessment of cancer

    The Regents of the University of California · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  27. US 10709705

    Aminopyrimidines as ALK inhibitors

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  28. US 10709703

    2,4-pyrimidinediamine compounds and their uses

    Rigel Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  29. US 10709665

    Zinc meloxicam complex microparticle multivesicular liposome formulations and processes for making the same

    Pacira Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  30. US 10711028

    Antimicrobial compounds, compositions, and uses thereof

    Lakewood Amedex, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  31. US 10711029

    Beta-d-2′-deoxy-2′-alpha-fluoro-2′-beta-c-substituted-4′fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection

    Atea Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  32. US 10709692

    Isoxazolidine derived inhibitors of receptor interacting protein kinase 1 (RIPK1)

    DENALI THERAPEUTICS INC. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  33. US 10709733

    Nonsurgical techniques for restoring tooth enamel

    Regents of the University of Minnesota · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  34. US 10709728

    Polynucleotide agents targeting angiotensinogen (AGT) and methods of use thereof

    Alnylam Pharmaceuticals, Inc. · Granted Tue Jul 14 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 09 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  35. US 10716843

    Immune enhancing recombinant dengue protein

    United States of America as represented by the Secretary of the Air Force · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  36. US 10716852

    Stable aqueous formulations of adalimumab

    Coherus BioSciences, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  37. US 10716808

    Methods and compositions to modulate hair growth

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  38. US 10716782

    LPT-723 and immune checkpoint inhibitor combinations and methods of treatment

    Biomed Valley Discoveries, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  39. US 10716789

    Co-crystals and pharmaceutical compositions comprising the same

    Vertex Pharmaceuticals Incorporated · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  40. US 10717799

    Copolymers as excipients for effective solubilization of poorly water-soluble substances from solid mixtures

    Regents of the University of Minnesota · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  41. US 10716770

    Nicotinic receptor non-competitive antagonists

    Catalyst Biosciences, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  42. US 10716809

    Methods of producing enriched populations of tumor reactive T cells from peripheral blood

    The United States of America, as represented by the Secretary, Department of Health and Human Services · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  43. US 10716869

    Radiolabeled macrocyclic EGFR inhibitor

    Oncodesign SA · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  44. US 10718778

    Compositions and methods for detecting protein sulfenylation

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  45. US 10717981

    Therapeutic compositions and methods of making and using the same

    Advanced ReGen Medical Technologies, LLC · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  46. US 10717765

    Compositions and methods for treating autoimmune and inflammatory disorders

    SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  47. US 10717764

    Therapeutically active compounds and their methods of use

    Agios Pharmaceuticals, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted
  48. US 10717993

    Methods and compositions for increased transgene expression

    Sangamo Therapeutics, Inc. · Granted Tue Jul 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) · Expires Mon Jul 16 2040 00:00:00 GMT+0000 (Coordinated Universal Time)

    granted

Frequently asked questions

How many pharma patents expire in 2040?

1,866 published patents in our USPTO index have expiration dates falling in calendar year 2040.