Intelligence · Clinical Pipeline

Phase III Pipeline Programs

Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Programs: 5,427

Quick answer

NovaPharmaNews tracks 5,427 phase iii pharmaceutical pipeline programs from ClinicalTrials.gov. Late-stage pivotal and registrational clinical programs nearing regulatory submission.

Top sponsors

18F-AV-1451

The George Institute

Maladie d' Alzheimer, Alzheimer's pathology

phase 3 small molecule active

1 trial
18F-DPA-714

Pari Pharma GmbH

Multiple sclerosis

phase 3 small molecule active

1 trial
18F-LBT-999

The George Institute

Comatose Traumatic Brain Injury patients

phase 3 small molecule active

1 trial
1:1:1 Blood Transfusion Ratio

United Therapeutics Europe Ltd

Trauma

phase 3 mab completed

1 trial
1mg elsunersen

Chongqing Precision Biotech Co., Ltd

Epileptic Encephalopathy

phase 3 small molecule active

1 trial
2 cycles induction chemotherapy

The First People's Hospital of Lianyungang

Locally Advanced Nasopharyngeal Carcinoma

phase 3 small molecule active

1 trial
2 mg Melatonin

United Therapeutics Europe Ltd

Anxiety

phase 3 small molecule completed

1 trial
2-mg Intravitreous Aflibercept Injection

Regeneron UK Limited

Proliferative Diabetic Retinopathy

phase 3 small molecule completed

1 trial
2.0 mg intravitreal aflibercept

Regeneron UK Limited

Diabetic Macular Edema

phase 3 small molecule completed

1 trial
20 mg VEC-162

Vanda Pharmaceuticals Netherlands B.V.

Insomnia

phase 3 small molecule completed

1 trial
20 mg sildenafil citrate by mouth

The First People's Hospital of Lianyungang

Pulmonary Hypertension

phase 3 small molecule active

1 trial
20mg/day PRAX-628 for 6 weeks then 30mg/day PRAX-628 for remaining 6 weeks

Chongqing Precision Biotech Co., Ltd

Focal Seizure

phase 3 small molecule active

1 trial
25 mg Ontamalimab

Takeda

Crohn's Disease

phase 3 small molecule completed

1 trial
25% AgNO3 solution followed by 5% NaF

The University of Hong Kong

Early Childhood Caries

phase 3 small molecule completed

1 trial
2mg Baricitinib

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Acute Ichemic Stroke

phase 3 small molecule active

1 trial
3-N-butylphthalide

Second Affiliated Hospital, School of Medicine, Zhejiang University

Multiple System Atrophy

phase 3 small molecule active

1 trial
3-N-butylphthalide

The First People's Hospital of Lianyungang

Multiple System Atrophy

phase 3 small molecule active

1 trial
3-dimensional conformal radiation therapy

United Therapeutics Europe Ltd

Head and Neck Cancer

phase 3 other active

1 trial
3-second SDF application

The University of Hong Kong

Early Childhood Caries

phase 3 other completed

1 trial
35 mg oral lyophilisate, 25 mg oral lyophilisate, 50 mg oral lyophilisate, VYDURA 75 mg oral lyophilisate

Pfizer Australia Pty Ltd

Acute Migraine (with or without aura)

phase 3 small molecule active

1 trial
36-71 months old children-experimental EV71 vaccine.

Sinovac Research and Development Co.,

Hand, Foot and Mouth Disease

phase 3 mab completed

1 trial
4-aminopyridine

United Therapeutics Europe Ltd

Spinal Muscular Atrophy

phase 3 small molecule completed

1 trial
40 mg/day vormatrogine for 12 weeks

Chongqing Precision Biotech Co., Ltd

Focal Epilepsy

phase 3 small molecule active

1 trial
400U /0.5ml EV71 vaccine

Sinovac Research and Development Co.,

Hand, Foot and Mouth Disease

phase 3 mab completed

1 trial
4D-150 IVT (3E10 vg/eye)

4D Molecular Therapeutics

Macular Neovascularization Secondary to Age-Related Macular Degeneration

phase 3 mab active

1 trial
4D-150 IVT (3E10 vg/eye)

4D Molecular Therapeutics

Neovascular Age-Related Macular Degeneration (nAMD)

phase 3 mab active

1 trial
5 mg Serlopitant Tablets

VYNE Therapeutics

Pruritus

phase 3 small molecule terminated

3 trials
5 mg Tadalafil

Eli Lilly and Company

Benign Prostate Hyperplasia

phase 3 small molecule completed

1 trial
5 mg prednisone

Ultragenyx UK Limited

Granulomatosis With Polyangiitis

phase 3 small molecule active

2 trials
5% Dextrose injection; Solution for injection/infusion, OPDIVO 10 mg/mL concentrate for solution for infusion., 0.9% Sodium Chloride injection; Solution for injection/infusion

Bristol-Myers Squibb Australia Pty Ltd

Hepatocellular Carcinoma

phase 3 small molecule active

1 trial
5% Lidocaine patch

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Herpes Zoster Pain

phase 3 small molecule completed

1 trial
5% cysteamine cream

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Melasma

phase 3 other completed

1 trial
5% minoxidil foam

Sunshine Guojian Pharmaceutical (Shanghai) Co.,

Androgenetic Alopecia

phase 3 small molecule active

1 trial
5-FU medac 50 mg/ml, Injektionslösung, Tecentriq 1 200 mg concentrate for solution for infusion, Docetaxel Accord 20 mg/1 ml concentrate for solution for infusion, Leucovorin 10 mg/ml Lösung zur Injektion/ Infusion, Oxaliplatin medac 5 mg/ml concentrate for solution for infusion

The George Institute

locally advanced resectable adenocarcinoma of the oesophagogastric junction or the stomach

phase 3 small molecule active

1 trial
5-Fluorouracil

Hoffmann-La Roche

Breast Cancer

phase 3 small molecule completed

1 trial
5-Fluoruracil

Hoffmann-La Roche

Gastric Cancer

phase 3 small molecule completed

1 trial
5-Fu/epirubicin/CTX following Docetaxel

Xiyuan Hospital of China Academy of Chinese Medical Sciences

Breast Cancer

phase 3 small molecule active

1 trial
5mg Serlopitant Tablets

VYNE Therapeutics

Pruritus

phase 3 small molecule completed

2 trials
6% Hydroxy-ethyl starch (130/0.4)

The George Institute

Intensive Care

phase 3 small molecule completed

1 trial
6% hydroxyethyl starch 130/0.4

Fresenius Kabi Australia Pty Limited

Hypovolemia

phase 3 small molecule completed

1 trial
6-Thio-2'-Deoxyguanosine

MAIA Biotechnology

Carcinoma, Non-Small-Cell Lung

phase 3 small molecule active

2 trials
6-month course of antiandrogen drugs

The First People's Hospital of Lianyungang

Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

phase 3 small molecule active

1 trial
60 mg ulixacaltamide

Chongqing Precision Biotech Co., Ltd

Essential Tremor

phase 3 small molecule active

1 trial
600 mg Ibuprofen

United Therapeutics Europe Ltd

Tibial Fractures

phase 3 small molecule active

1 trial
601 1.25mg

Sunshine Guojian Pharmaceutical (Shanghai) Co.,

Branch Retinal Vein Occlusion

phase 3 small molecule completed

2 trials
608

Sunshine Guojian Pharmaceutical (Shanghai) Co.,

Axial Spondyloarthritis, Non-Radiographic

phase 3 small molecule active

1 trial
608 Q2W

Sunshine Guojian Pharmaceutical (Shanghai) Co.,

Psoriasis

phase 3 small molecule completed

1 trial
608 Q2W

Sunshine Guojian Pharmaceutical (Shanghai) Co.,

Plaque Psoriasis Patients

phase 3 small molecule active

1 trial

Frequently asked questions

How many Phase III pipeline programs are in the directory?

5,427 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs

Quick answer

Top sponsors

18F-AV-1451

18F-DPA-714

18F-LBT-999

1:1:1 Blood Transfusion Ratio

1mg elsunersen

2 cycles induction chemotherapy

2 mg Melatonin

2-mg Intravitreous Aflibercept Injection

2.0 mg intravitreal aflibercept

20 mg VEC-162

20 mg sildenafil citrate by mouth

20mg/day PRAX-628 for 6 weeks then 30mg/day PRAX-628 for remaining 6 weeks

25 mg Ontamalimab

25% AgNO3 solution followed by 5% NaF

2mg Baricitinib

3-N-butylphthalide

3-N-butylphthalide

3-dimensional conformal radiation therapy

3-second SDF application

35 mg oral lyophilisate, 25 mg oral lyophilisate, 50 mg oral lyophilisate, VYDURA 75 mg oral lyophilisate

36-71 months old children-experimental EV71 vaccine.

4-aminopyridine

40 mg/day vormatrogine for 12 weeks

400U /0.5ml EV71 vaccine

4D-150 IVT (3E10 vg/eye)

4D-150 IVT (3E10 vg/eye)

5 mg Serlopitant Tablets

5 mg Tadalafil

5 mg prednisone

5% Dextrose injection; Solution for injection/infusion, OPDIVO 10 mg/mL concentrate for solution for infusion., 0.9% Sodium Chloride injection; Solution for injection/infusion

5% Lidocaine patch

5% cysteamine cream

5% minoxidil foam

5-FU medac 50 mg/ml, Injektionslösung, Tecentriq 1 200 mg concentrate for solution for infusion, Docetaxel Accord 20 mg/1 ml concentrate for solution for infusion, Leucovorin 10 mg/ml Lösung zur Injektion/ Infusion, Oxaliplatin medac 5 mg/ml concentrate for solution for infusion

5-Fluorouracil

5-Fluoruracil

5-Fu/epirubicin/CTX following Docetaxel

5mg Serlopitant Tablets

6% Hydroxy-ethyl starch (130/0.4)

6% hydroxyethyl starch 130/0.4

6-Thio-2'-Deoxyguanosine

6-month course of antiandrogen drugs

60 mg ulixacaltamide

600 mg Ibuprofen

601 1.25mg

608

608 Q2W

608 Q2W

Frequently asked questions

Stay Ahead in Pharma