Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 98 of 151
  1. PF-00547659

    Takeda

    Crohn's Disease

    phase 2 small molecule completed

    1 trial
  2. PF-00547659 SC injection

    Takeda

    Crohn's Disease

    phase 2 small molecule completed

    1 trial
  3. PF-03446962

    Pfizer

    Carcinoma, Hepatocellular

    phase 2 small molecule terminated

    1 trial
  4. PF-04236921 SC injection

    Pfizer

    Crohn's Disease

    phase 2 small molecule completed

    1 trial
  5. PF-04457845

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Dependence

    phase 2 small molecule completed

    1 trial
  6. PF-05190457

    BRIGHT MINDS BIOSCIENCES INC.

    Alcoholism

    phase 2 small molecule terminated

    1 trial
  7. PF-06650833

    Pfizer

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial
  8. PF-06835375

    Pfizer

    Primary Immune Thrombocytopenia

    phase 2 mab active

    1 trial
  9. PF-07850327 round

    Pfizer Australia Pty Ltd

    ADVANCED OR METASTATIC BREAST CANCER

    phase 2 small molecule active

    1 trial
  10. PF-07868489

    Pfizer Australia Pty Ltd

    Pulmonary Arterial Hypertension

    phase 2 small molecule active

    1 trial
  11. PF614

    Ensysce Biosciences

    Acute Pain

    phase 2 small molecule completed

    1 trial
  12. PFL721CI101

    Pierre Fabre Medicament

    Locally Advanced or Metastatic Non-Small Cell Lung Cancer

    phase 2 other active

    1 trial
  13. PG2

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Stroke

    phase 2 small molecule completed

    1 trial
  14. PH-10

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Atopic Dermatitis

    phase 2 small molecule completed

    1 trial
  15. PH-10 (0.001% Rose Bengal)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Psoriasis

    phase 2 small molecule completed

    1 trial
  16. PH-10 (0.002% Rose Bengal)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Psoriasis

    phase 2 small molecule completed

    1 trial
  17. PH-10 (rose bengal disodium 0.001%)

    PROVECTUS BIOPHARMACEUTICALS, INC.

    Plaque Psoriasis

    phase 2 small molecule terminated

    1 trial
  18. PH-797804

    Pfizer

    Pulmonary Disease, Chronic Obstructive

    phase 2 small molecule completed

    1 trial
  19. PH-ICKPD1-02/21

    Philogen S.p.A.

    Patients with diagnosis of unresectable clinical stage III or IV metastatic melanoma, with presence of injectable cutaneous, subcutaneous or nodal lesions and resistant to or progressing upon anti-PD1 immunotherapy

    phase 2 small molecule active

    1 trial
  20. PH-L19TNFSARC-03/18

    Philogen S.p.A.

    Unresectable and/or metastatic soft-tissue sarcoma after failure of at least two prior systemic therapy regimens.

    phase 2 small molecule active

    1 trial
  21. PH94B

    Vistagen Therapeutics

    Adjustment Disorder With Anxious Mood

    phase 2 small molecule completed

    1 trial
  22. PHE885

    Novartis Pharmaceuticals

    Multiple Myeloma

    phase 2 mab terminated

    1 trial
  23. PHERFLOT

    The George Institute

    HER2-positive, localized esophagogastric adenocarcinoma

    phase 2 small molecule active

    1 trial
  24. PHITAH

    Lxo Ireland Designated Activity Company

    Basal Cell Carcinoma

    phase 2 mab active

    1 trial
  25. PI-88

    Biotech Pharmaceutical Co.,

    Lung Cancer

    phase 2 small molecule completed

    1 trial
  26. PI3K inhibitor

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Lymphoma, T-Cell

    phase 2 small molecule active

    1 trial
  27. PIK3CA inhibitor

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Breast Neoplasm

    phase 2 small molecule active

    1 trial
  28. PIO

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 2 small molecule terminated

    1 trial
  29. PIPE-307 Dose A

    Contineum Therapeutics

    Relapsing Remitting Multiple Sclerosis

    phase 2 small molecule completed

    1 trial
  30. PIPE-505

    Contineum Therapeutics

    Sensorineural Hearing Loss

    phase 2 small molecule completed

    1 trial
  31. PIPE-791 Dose A

    Contineum Therapeutics

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial
  32. PIROXICAM, LIDOCAINE HYDROCHLORIDE

    The George Institute

    lateral epicondylitis

    phase 2 small molecule active

    1 trial
  33. PIRTOBRUTINIB

    Fondazione Telethon ETS

    Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial
  34. PITAC_ MaPEPi

    Sana Biotechnology

    Pleural carcinosis

    phase 2 small molecule active

    1 trial
  35. PIVEKIMAB SUNIRINE

    AbbVie Deutschland GmbH & Co. KG

    Acute Myeloid Leukemia and other blood cancers

    phase 2 small molecule active

    1 trial
  36. PL2200

    Protalix BioTherapeutics

    Gastroduodenal Ulceration

    phase 2 small molecule completed

    1 trial
  37. PL3100

    Protalix BioTherapeutics

    Gastroduodenal Ulcerations

    phase 2 small molecule completed

    1 trial
  38. PLD and Carboplatin

    The First People's Hospital of Lianyungang

    Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  39. PLN-74809

    PLIANT THERAPEUTICS, INC.

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule completed

    4 trials
  40. PLN-74809

    PLIANT THERAPEUTICS, INC.

    Acute Respiratory Distress Syndrome

    phase 2 small molecule terminated

    1 trial
  41. PLN-74809

    PLIANT THERAPEUTICS, INC.

    Primary Sclerosing Cholangitis

    phase 2 small molecule completed

    1 trial
  42. PM14, IRINOTECAN

    Lacuna Pharma Pty Ltd

    Patients with Selected Advanced Solid Tumors

    phase 2 small molecule active

    1 trial
  43. PM14-A-001-17

    Lacuna Pharma Pty Ltd

    Advanced Solid Tumors

    phase 2 other active

    1 trial
  44. PM359

    Prime Medicine

    Chronic Granulomatous Disease

    phase 2 mab active

    1 trial
  45. PM8002

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Locally Advanced Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  46. PMR-EC-1206

    Astellas Pharma GmbH

    Prophylaxis of primary liver, kidney, heart, lung, and intestinal organ transplant rejection

    phase 2 small molecule active

    1 trial
  47. PN-943

    Protagonist Therapeutics, Inc

    Ulcerative Colitis Chronic Moderate

    phase 2 small molecule completed

    1 trial
  48. POINT

    Fondazione Telethon ETS

    Adult patients affected by recurrent/metastatic, platinum resistant nasopharyngeal cancer

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.