Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. PAXALISIB

    KAZIA THERAPEUTICS LTD

    Primary Central Nervous System Lymphoma

    phase 2 small molecule active

    1 trial
  2. PBCAR20A

    Chongqing Precision Biotech Co., Ltd

    Non-Hodgkin's Lymphoma, Relapsed

    phase 2 gene therapy completed

    1 trial
  3. PBGENE-DMD (IV)

    Chongqing Precision Biotech Co., Ltd

    Duchenne Muscular Dystrophy With Mutations Amenable to PBGENE-DMD

    phase 2 mab active

    1 trial
  4. PBSC

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stem Cell Transplantation, Hematopoietic

    phase 2 mab active

    1 trial
  5. PBSC transplantation

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Liver Cirrhosis

    phase 2 other active

    1 trial
  6. PC-IIT-003

    The First People's Hospital of Lianyungang

    Pancreatic Cancer

    phase 2 small molecule active

    1 trial
  7. PC-SOD

    The First People's Hospital of Lianyungang

    Myocardial Reperfusion Injury

    phase 2 small molecule active

    1 trial
  8. PC14586

    PMV Pharmaceuticals

    Locally Advanced or Metastatic Solid Tumors Harboring a TP53 Y220C Mutation

    phase 2 small molecule active

    1 trial
  9. PCAR-019 (anti-CD19 CAR-T cells)

    The First People's Hospital of Lianyungang

    Acute Lymphocytic Leukemia

    phase 2 mab active

    1 trial
  10. PCI

    Rhythm Pharmaceuticals Netherlands B.V.

    Myocardial Infarction

    phase 2 other completed

    1 trial
  11. PCN-101

    Chongqing Precision Biotech Co., Ltd

    Treatment Resistant Depression

    phase 2 small molecule completed

    1 trial
  12. PCS12852

    Processa Pharmaceuticals

    Gastroparesis

    phase 2 small molecule completed

    1 trial
  13. PCS499

    Processa Pharmaceuticals

    Necrobiosis Lipoidica

    phase 2 small molecule completed

    2 trials
  14. PCS6422 and capecitabine

    Processa Pharmaceuticals

    Breast Cancer

    phase 2 small molecule active

    1 trial
  15. PCYC-1146-IM

    AbbVie Deutschland GmbH & Co. KG

    Chronic Graft Versus Host Disease (cGVHD)

    phase 2 small molecule active

    1 trial
  16. PD -1/PD-L1 monoclonal antibody plus radiotherapy and liver transplantation

    The First People's Hospital of Lianyungang

    Locally Advanced Perihilar Cholangiocarcinoma

    phase 2 other active

    1 trial
  17. PD 0332991

    Pfizer

    Breast Cancer

    phase 2 small molecule completed

    1 trial
  18. PD-1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Rectal Cancer Patients

    phase 2 small molecule active

    1 trial
  19. PD-1 Inhibitor plus Chemotherapy

    Sichuan University

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  20. PD-1 antibody Sintilimab

    The First People's Hospital of Lianyungang

    Multiple Primary Lung Cancers

    phase 2 small molecule active

    1 trial
  21. PD-1 inhbitor+SHR0302

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  22. PD-1 inhibitor

    The First People's Hospital of Lianyungang

    Advanced NSCLC

    phase 2 small molecule active

    1 trial
  23. PD-1/CTLA-4 Dual Functional Antibody

    The First People's Hospital of Lianyungang

    Bile Duct Carcinoma

    phase 2 small molecule active

    1 trial
  24. PD-1/PD-L1 inhibitors

    BEONE MEDICINES AUS PTY LTD

    Borderline Resectable Carcinoma

    phase 2 small molecule active

    1 trial
  25. PD-1inhibitor

    Shanghai Chest Hospital

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  26. PD-L1 peptide

    IO Biotech

    Smoldering Multiple Myeloma

    phase 2 mab terminated

    1 trial
  27. PD-L1, PD-L2 peptides with Montanide ISA51

    IO Biotech

    Chronic Lymphocytic Leukemia

    phase 2 other completed

    1 trial
  28. PDC-1421 Capsule

    ABVC BIOPHARMA, INC.

    Attention-Deficit Hyperactivity Disorder (ADHD)

    phase 2 small molecule completed

    1 trial
  29. PDC-LUNG-101

    Lacuna Pharma Pty Ltd

    Non-small-cell lung cancer

    phase 2 small molecule active

    1 trial
  30. PDI-192

    Chongqing Precision Biotech Co., Ltd

    Atopic Dermatitis

    phase 2 small molecule completed

    1 trial
  31. PDI-320

    Chongqing Precision Biotech Co., Ltd

    Rosacea

    phase 2 small molecule active

    1 trial
  32. PDY13949

    Genzyme Europe B.V.

    Gaucher disease type 3, Gaucher disease type 1

    phase 2 small molecule active

    1 trial
  33. PEG-IFNα

    Vir Biotechnology

    Chronic Hepatitis B Virus Infection

    phase 2 mab active

    1 trial
  34. PEG-liposomal prednisolone sodium phosphate

    Lakefront Biotherapeutics NV

    Acute Exacerbation of Remitting Relapsing Multiple Sclerosis

    phase 2 small molecule terminated

    1 trial
  35. PEG-somatropin

    Changchun GeneScience Pharmaceutical Co.,

    Dwarfism

    phase 2 small molecule active

    1 trial
  36. PEG-somatropin

    The First People's Hospital of Lianyungang

    Short Stature Children Born Small for Gestational Age (SGA)

    phase 2 mab active

    1 trial
  37. PEG-somatropin

    The First People's Hospital of Lianyungang

    Dwarfism

    phase 2 small molecule active

    1 trial
  38. PEGFILGRASTIM , Rinatabart Sesutecan

    Genmab A/S

    Locally advanced or metastatic Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  39. PEGINTERFERON ALFA-2A for Metastatic Melanoma

    Disc Medicine

    Metastatic Melanoma

    phase 2 small molecule active

    1 trial
  40. PEGPH20

    HALOZYME THERAPEUTICS, INC.

    Metastatic Pancreatic Cancer

    phase 2 small molecule completed

    1 trial
  41. PEGPH20

    HALOZYME THERAPEUTICS, INC.

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule active

    1 trial
  42. PEGPH20

    HALOZYME THERAPEUTICS, INC.

    Metastatic Pancreatic Adenocarcinoma

    phase 2 small molecule completed

    1 trial
  43. PELICAN-IPC 2015-016

    The George Institute

    Breast cancer

    phase 2 small molecule active

    1 trial
  44. PEMBROLIZUMAB

    Pari Pharma GmbH

    Kaposi's sarcoma

    phase 2 small molecule active

    1 trial
  45. PEMBROLIZUMAB, PM54

    Lacuna Pharma Pty Ltd

    Advanced malignancies

    phase 2 small molecule active

    1 trial
  46. PENNVAX-GP

    INOVIO PHARMACEUTICALS, INC.

    HIV-1-infection

    phase 2 mab completed

    1 trial
  47. PERLA

    Zentiva k.s.

    Patients with moderate or severe oedema on a long-term treatment with amlodipine

    phase 2 small molecule active

    1 trial
  48. PEX168 or placebo

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Type 2 Diabetes

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.