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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 96 of 151

  1. Oral MRT-2359

    Monte Rosa Therapeutics

    NSCLC

    phase 2 small molecule active

    1 trial

  2. Oral Naltrexone

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 2 small molecule completed

    1 trial

  3. Oral arsenic trioxide

    The University of Hong Kong

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial

  4. Oral hexavalent reassortant rotavirus attenuated live vaccine

    Sinovac Research and Development Co.,

    Rotavirus Gastroenteritis

    phase 2 mab active

    2 trials

  5. Oral levetiracetam

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Neonatal Seizures

    phase 2 small molecule terminated

    1 trial

  6. Oral treprostinil

    United Therapeutics Europe Ltd

    Systemic Sclerosis

    phase 2 small molecule completed

    1 trial

  7. Oral versus topical antibioitics

    United Therapeutics Europe Ltd

    Chronic Rhinosinusitis (Diagnosis)

    phase 2 small molecule terminated

    1 trial

  8. Orelabrutinib

    The First People's Hospital of Lianyungang

    MALT Lymphoma

    phase 2 small molecule active

    1 trial

  9. Orelabrutinib

    The First People's Hospital of Lianyungang

    Primary Central Nervous System Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial

  10. Orelabrutinib

    The First People's Hospital of Lianyungang

    Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

    phase 2 small molecule active

    1 trial

  11. Orelabrutinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Follicular Lymphoma

    phase 2 small molecule active

    1 trial

  12. Orelabrutinib

    The First People's Hospital of Lianyungang

    Marginal Zone Lymphoma(MZL)

    phase 2 small molecule active

    1 trial

  13. Organoid-guided treatment

    The First People's Hospital of Lianyungang

    HER2-negative Breast Cancer

    phase 2 small molecule active

    1 trial

  14. Orgovyx 120 mg film-coated tablets

    Fondazione Telethon ETS

    Prostate Cancer

    phase 2 small molecule active

    1 trial

  15. Orteronel 300mg BID

    Takeda

    Metastatic or Advanced Non-resectable Granulosa Cell Ovarian Tumors

    phase 2 small molecule terminated

    1 trial

  16. Oshadi Icp

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetes Mellitus, Insulin-Dependent, 1

    phase 2 small molecule completed

    1 trial

  17. Osilodrostat

    Novartis Pharmaceuticals

    Cushing's Syndrome

    phase 2 small molecule completed

    1 trial

  18. Osimertinib + Savolitinib

    AstraZeneca

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  19. Osimertinib 80 mg/40 mg

    AstraZeneca

    Stage II-IIIB Non-small Cell Lung Carcinoma

    phase 2 small molecule active

    1 trial

  20. Osteosheet(r)

    Hospital Authority, Hong Kong

    Orbital Trauma

    phase 2 other completed

    1 trial

  21. Other: Placebo

    GlaxoSmithKline

    Menopausal and Female Climacteric States

    phase 2 small molecule completed

    1 trial

  22. Oxaliplatin

    Universal Integrated

    Previously Treated Metastatic Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  23. Oxaliplatin

    Regeneron UK Limited

    Colorectal Cancer

    phase 2 small molecule active

    1 trial

  24. Oxaliplatin

    Sanofi Pasteur

    Uterine Neoplasms

    phase 2 small molecule terminated

    1 trial

  25. Oxbryta 500 mg film-coated tablets

    Pari Pharma GmbH

    sickle cell disease

    phase 2 small molecule active

    1 trial

  26. Oxycyte

    TENAX THERAPEUTICS, INC.

    Traumatic Brain Injury

    phase 2 small molecule terminated

    2 trials

  27. Oxylanthanum Carbonate

    Unicycive Therapeutics

    Chronic Kidney Disease Requiring Chronic Dialysis

    phase 2 small molecule completed

    1 trial

  28. Oxytocin

    United Therapeutics Europe Ltd

    Alcohol Use Disorder

    phase 2 small molecule completed

    1 trial

  29. Oxytocin

    BRIGHT MINDS BIOSCIENCES INC.

    Social Cognition

    phase 2 small molecule completed

    1 trial

  30. Oxytocin nasal spray

    COGNITION THERAPEUTICS INC

    Cold Exposure

    phase 2 small molecule completed

    1 trial

  31. Oxytocin nasal spray

    COGNITION THERAPEUTICS INC

    Oxidative Stress

    phase 2 small molecule completed

    1 trial

  32. Ozempic solution for Craving for and use of chemsex…

    The George Institute

    Craving for and use of chemsex-related drugs

    phase 2 small molecule active

    1 trial

  33. P-1037

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial

  34. P-SP420-THAL-01

    Lacuna Pharma Pty Ltd

    transfusion-dependent α- or β-thalassemia or low-risk myelodysplastic syndromes

    phase 2 other active

    1 trial

  35. P120142

    Pari Pharma GmbH

    Patient with newly diagnosed (≤ 3 months) type 1 diabetes stage 3

    phase 2 small molecule active

    1 trial

  36. P150941J

    Pari Pharma GmbH

    Adults diagnosed with SJS-TEN with at least 10% of body surface area involved

    phase 2 small molecule active

    1 trial

  37. P160906J

    Pari Pharma GmbH

    Patients displaying a non-classified, severe and resistant inflammatory disease

    phase 2 small molecule active

    1 trial

  38. P160909

    Pari Pharma GmbH

    Takayasu arteritis

    phase 2 small molecule active

    1 trial

  39. P160954J

    Pari Pharma GmbH

    Adults with non-contrast-enhancing diffuse brainstem gliomas with non-threatening infiltrative clinical and/or radiological progression, Adult brain stem gliomas

    phase 2 other active

    1 trial

  40. P170922J

    Pari Pharma GmbH

    Minimal Change Nephrotic Syndrom

    phase 2 small molecule active

    1 trial

  41. P276-00

    Piramal Critical Care B.V.

    Melanoma

    phase 2 small molecule completed

    1 trial

  42. P38 Inhibitor (4) 150mg

    Hoffmann-La Roche

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  43. PA-824

    BRIGHT MINDS BIOSCIENCES INC.

    Tuberculosis

    phase 2 small molecule completed

    2 trials

  44. PA-824

    BRIGHT MINDS BIOSCIENCES INC.

    Pulmonary Tuberculosis

    phase 2 small molecule completed

    3 trials

  45. PACLITAXEL AHCL /ml for Head and neck squamous cell carcinoma

    Ningbo Cancer Hospital

    Head and neck squamous cell carcinoma

    phase 2 small molecule active

    1 trial

  46. PARP inhibitor 2X-121

    Allarity Therapeutics

    Metastatic Breast Cancer

    phase 2 small molecule completed

    1 trial

  47. PASSION

    Verona Pharma Ireland Limited

    Patients with metastatic PDAC, who have not progressed following completion of at least 16 weeks (can be more) of any multiagent first-line chemotherapy

    phase 2 small molecule active

    1 trial

  48. PAUF-I

    Lacuna Pharma Pty Ltd

    Advanced and/or metastatic pancreatic adenocarcinoma

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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