Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. ORMD-0801

    ORAMED PHARMACEUTICALS INC.

    Diabetes Type 2

    phase 2 small molecule completed

    1 trial
  2. ORMD-0801 (Insulin) capsule 8 mg BD

    ORAMED PHARMACEUTICALS INC.

    Diabetes Mellitus, Type 2

    phase 2 small molecule completed

    1 trial
  3. ORMD-0801 Capsules

    ORAMED PHARMACEUTICALS INC.

    Diabetes Mellitus Type 1

    phase 2 mab completed

    1 trial
  4. ORMD-0801 Dose # 1

    ORAMED PHARMACEUTICALS INC.

    Diabetes Mellitus Type 2

    phase 2 small molecule completed

    1 trial
  5. ORMD-0801 QD

    ORAMED PHARMACEUTICALS INC.

    Nonalcoholic Steatohepatitis (NASH)

    phase 2 small molecule completed

    1 trial
  6. ORMD-0801 Treatment A

    ORAMED PHARMACEUTICALS INC.

    Type 1 Diabetes

    phase 2 small molecule completed

    1 trial
  7. ORMD-0801 capsules- 2x8mg

    ORAMED PHARMACEUTICALS INC.

    Type 1 Diabetes

    phase 2 small molecule completed

    1 trial
  8. ORX750

    Centessa Pharmaceuticals plc

    Narcolepsy Type 1

    phase 2 small molecule active

    2 trials
  9. ORX750-0201

    Centessa Pharmaceuticals plc

    Narcolepsy and Idiopathic Hypersomnia

    phase 2 small molecule active

    1 trial
  10. ORX750-202

    Centessa Pharmaceuticals plc

    Narcolepsy and Idiopathic Hypersomnia

    phase 2 small molecule active

    1 trial
  11. ORY-2001 Low dose

    BRIGHT MINDS BIOSCIENCES INC.

    Mild to Moderate Alzheimer's Disease

    phase 2 small molecule completed

    1 trial
  12. OT-101

    Oncotelic Therapeutics

    COVID-19

    phase 2 small molecule active

    1 trial
  13. OT-101

    Oncotelic Therapeutics

    Malignant Pleural Mesothelioma

    phase 2 small molecule active

    1 trial
  14. OVX836 480µg

    Harmony Biosciences Holdings

    Influenza

    phase 2 mab completed

    1 trial
  15. OVX836 shot

    Harmony Biosciences Holdings

    Vaccine-Preventable Diseases

    phase 2 mab completed

    1 trial
  16. OXY-APS

    The George Institute

    schizophrenia or other primary psychotic disorders (SSD)

    phase 2 small molecule active

    1 trial
  17. OZ439

    CNS Pharmaceuticals

    Malaria

    phase 2 small molecule completed

    1 trial
  18. Obatoclax

    Teva Pharma GmbH

    AML

    phase 2 small molecule completed

    1 trial
  19. Obatoclax

    Teva Pharma GmbH

    Extensive-stage Small Cell Lung Cancer

    phase 2 small molecule completed

    1 trial
  20. Obatoclax Mesylate

    Teva Pharma GmbH

    Metastatic Melanoma

    phase 2 small molecule terminated

    1 trial
  21. Obatoclax mesylate

    Teva Pharma GmbH

    Lymphoma, Follicular

    phase 2 small molecule completed

    1 trial
  22. Obatoclax mesylate

    Teva Pharma GmbH

    Mantle-Cell Lymphoma

    phase 2 small molecule completed

    1 trial
  23. Obatoclax mesylate (GX15-070MS)

    Teva Pharma GmbH

    Hodgkin's Lymphoma

    phase 2 small molecule completed

    1 trial
  24. Obatoclax mesylate (GX15-070MS)

    Teva Pharma GmbH

    Myelofibrosis

    phase 2 small molecule completed

    1 trial
  25. Obatoclax mesylate (GX15-070MS)

    Teva Pharma GmbH

    Myelodysplastic Syndromes

    phase 2 small molecule completed

    1 trial
  26. Obatoclax mesylate 250 ml

    Teva Pharma GmbH

    Lung Cancer

    phase 2 small molecule completed

    1 trial
  27. Obecabtagene Autoleucel

    Autolus GmbH

    Acute Lymphoblastic Leukemia

    phase 2 small molecule active

    1 trial
  28. Obecabtagene autoleucel

    Autolus GmbH

    Acute Lymphocytic Leukemia (ALL)

    phase 2 small molecule active

    1 trial
  29. Obecabtagene autoleucel

    Autolus GmbH

    Lupus Nephritis

    phase 2 mab active

    1 trial
  30. Obexelimab

    Zenas BioPharma

    Relapsing Multiple Sclerosis

    phase 2 small molecule active

    1 trial
  31. Obexelimab

    Zenas BioPharma

    Systemic Lupus Erythematosus

    phase 2 small molecule active

    1 trial
  32. Obinutuzumab

    The First People's Hospital of Lianyungang

    Large B-cell Lymphoma

    phase 2 small molecule active

    1 trial
  33. Obinutuzumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Marginal Zone Lymphoma

    phase 2 small molecule active

    1 trial
  34. Obinutuzumab

    Adaptive Biotechnologies Corp

    Mantle Cell Lymphoma

    phase 2 mab active

    1 trial
  35. Obinutuzumab Injection [Gazyva]

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Immune Thrombocytopenia

    phase 2 small molecule active

    2 trials
  36. Ocaliva 5 mg film-coated tablets

    Lacuna Pharma Pty Ltd

    Primary biliary cholangitis

    phase 2 small molecule active

    1 trial
  37. Ocrelizumab

    Hoffmann-La Roche

    Rheumatoid Arthritis

    phase 2 small molecule terminated

    1 trial
  38. Octacalcium phosphate

    The First People's Hospital of Lianyungang

    Tooth Extraction

    phase 2 other completed

    1 trial
  39. Octreotide Acetate

    United Therapeutics Europe Ltd

    Liver Transplantation

    phase 2 small molecule active

    1 trial
  40. Odomzo 200 mg hard capsules

    Fondazione Telethon ETS

    locally advanced basal cell carcinoma

    phase 2 small molecule active

    1 trial
  41. Odronextamab

    Regeneron UK Limited

    Recurrent Diffuse Large B-Cell Lymphoma

    phase 2 mab active

    1 trial
  42. Odronextamab

    Regeneron UK Limited

    B-cell Non-Hodgkin Lymphoma (B-NHL)

    phase 2 small molecule active

    2 trials
  43. Odronextamab

    Regeneron UK Limited

    Follicular Lymphoma

    phase 2 mab active

    1 trial
  44. Olaparib

    United Therapeutics Europe Ltd

    Bile Duct Adenocarcinoma

    phase 2 small molecule active

    1 trial
  45. Olaparib Continuous (28-Day cycle) 300 mg BD.

    AstraZeneca

    Metastatic Triple Negative Breast Cancer

    phase 2 small molecule active

    1 trial
  46. Olatorepatide

    Regeneron UK Limited

    Overweight or Obesity

    phase 2 small molecule active

    1 trial
  47. Olinciguat

    Cyclerion Therapeutics

    Achalasia

    phase 2 small molecule terminated

    1 trial
  48. Olorofim

    Biotech Pharmaceutical Co.,

    Invasive Fungal Infections

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.