Intelligence · Clinical Pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs
7,238

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NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

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  1. Olverembatinib

    The First People's Hospital of Lianyungang

    Philadelphia-Positive ALL

    phase 2 small molecule active

    1 trial
  2. Olverembatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

    phase 2 small molecule completed

    1 trial
  3. Olverembatinib+INO

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HSCT

    phase 2 small molecule active

    1 trial
  4. Omacetaxine

    Teva Pharma GmbH

    Myelodysplastic Syndromes

    phase 2 small molecule terminated

    1 trial
  5. Omacetaxine

    Teva Pharma GmbH

    Leukemia

    phase 2 small molecule terminated

    2 trials
  6. Omacetaxine

    Teva Pharma GmbH

    Acute Myelogenous Leukemia (AML)

    phase 2 small molecule terminated

    1 trial
  7. Omacetaxine mepesuccinate

    Teva Pharma GmbH

    Chronic Myeloid Leukemia

    phase 2 small molecule completed

    3 trials
  8. Omega 3 pentaenoic acid

    Matinas BioPharma Holdings

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial
  9. Omnitram Oral Tablet

    BRIGHT MINDS BIOSCIENCES INC.

    Diabetic Neuropathies

    phase 2 small molecule completed

    1 trial
  10. Omomyc

    The George Institute

    Advanced High-Grade Osteosarcoma

    phase 2 small molecule active

    1 trial
  11. Onapristone

    Context Therapeutics

    ER-positive Breast Cancer

    phase 2 small molecule terminated

    1 trial
  12. Onapristone ER

    Context Therapeutics

    Granulosa Cell Ovarian Cancer

    phase 2 small molecule completed

    1 trial
  13. OncoTICE® powder for instillation fluid for intravesical use containing 2-8 x 108 CFU Tice BCG., N-803 (NAI), OncoTICE® 2-8 x 108 vermehrungsfähige Einheiten Pulver zur Herstellung einer Suspension zur intravesikalen Instillation

    Immunitybio Ireland Limited

    Non-Muscle Invasive Bladder Cancer

    phase 2 small molecule active

    1 trial
  14. Ondansetron

    BRIGHT MINDS BIOSCIENCES INC.

    Amphetamine-Related Disorders

    phase 2 small molecule completed

    1 trial
  15. Ondansetron

    Takeda

    Nausea

    phase 2 small molecule completed

    1 trial
  16. Ondansetron (ODFS)

    Aquestive Therapeutics

    Nausea and Vomiting, Postoperative

    phase 2 small molecule completed

    1 trial
  17. Ondansetron Aurobindo 8 mg Filmtabletten, Dexamethasone 4 mg tablets, ZYPREXA 2.5 mg coated tablets, SELINEXOR, Bortezomib Accord 3.5 mg powder for solution for injection

    Karyopharm Therapeutics Inc

    Penta-refractory multiple myeloma and triple-class refractory multiple myeloma

    phase 2 small molecule active

    1 trial
  18. Online adaptive SBRT

    Sun Yat-sen University

    Adaptive Radiotherapy

    phase 2 other active

    1 trial
  19. Ontruzant 420 mg powder for concentrate for solution for infusion, Oxaliplatin onkovis 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung, KEYTRUDA 25 mg/mL concentrate for solution for infusion, TAXOTERE 20 mg/1 ml concentrate for solution for infusion, Oncofolic 50 mg/ml, Injektions-/Infusionslösung, 5-FU medac 50 mg/ml, Injektionslösung

    The George Institute

    HER2-positive, localized esophagogastric adenocarcinoma

    phase 2 small molecule active

    1 trial
  20. Onvansertib

    Cardiff Oncology

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    2 trials
  21. Onvansertib

    Cardiff Oncology

    Pancreatic Cancer

    phase 2 small molecule active

    1 trial
  22. Onvansertib

    Cardiff Oncology

    Pancreatic Ductal Adenocarcinoma

    phase 2 small molecule completed

    1 trial
  23. Onvansertib

    Cardiff Oncology

    Metastatic Castration-Resistant Prostate Cancer

    phase 2 small molecule completed

    1 trial
  24. Onvansertib

    Cardiff Oncology

    Small-cell Lung Cancer

    phase 2 small molecule active

    1 trial
  25. Onvansertib

    Cardiff Oncology

    Breast Cancer

    phase 2 small molecule active

    1 trial
  26. Onvansertib

    Cardiff Oncology

    Acute Myeloid Leukemia

    phase 2 small molecule completed

    1 trial
  27. Onvansertib

    Cardiff Oncology

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial
  28. Opaganib

    Apogee Therapeutics

    Multiple Myeloma

    phase 2 small molecule terminated

    1 trial
  29. Opaganib

    RedHill Biopharma

    Coronavirus Infections

    phase 2 small molecule completed

    1 trial
  30. Open Label Selinexor

    Karyopharm Therapeutics Inc

    Thymoma

    phase 2 small molecule terminated

    1 trial
  31. Open Mini-Laparotomy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hydrocephalus

    phase 2 other active

    1 trial
  32. Open-Label

    Jazz Pharmaceuticals Ireland Limited

    Chronic Obstructive Pulmonary Disease

    phase 2 small molecule terminated

    1 trial
  33. Open-label, safety, tolerability and proof of concept study to evaluate the use of ANXV (recombinant human Annexin A5 protein) in the treatment of patients with either Diabetic Retinopathy or recent onset Retinal Vein Occlusion

    Lacuna Pharma Pty Ltd

    Diabetic Retinopathy, Retinal Vein Occlusion

    phase 2 other active

    1 trial
  34. Opevesostat, -, CABAZITAXEL , -, FLUDROCORTISONE , Olaparib, HYDROCORTISONE , DEXAMETHASONE , -, -, -, -, Olaparib, DOCETAXEL , -

    Merck Sharp and Dohme

    Metastatic castration resistant prostate cancer (mCRPC)

    phase 2 small molecule active

    1 trial
  35. Opioid-Related Disorders

    BRIGHT MINDS BIOSCIENCES INC.

    Heroin Dependence

    phase 2 small molecule terminated

    3 trials
  36. Oral Budesonide Suspension (MB-9)

    Takeda

    Eosinophilic Esophagitis (EoE)

    phase 2 small molecule completed

    1 trial
  37. Oral CEP-701

    Teva Pharma GmbH

    Myeloma

    phase 2 small molecule terminated

    1 trial
  38. Oral Chinese Herbal Medicine of Clearing heat and Cooling blood therapy

    The First People's Hospital of Lianyungang

    Psoriasis

    phase 2 small molecule active

    1 trial
  39. Oral Encochleated Amphotericin B (CAMB)

    Matinas BioPharma Holdings

    Vulvovaginal Candidiases

    phase 2 small molecule terminated

    1 trial
  40. Oral Encochleated Amphotericin B (CAMB)

    Matinas BioPharma Holdings

    Vulvovaginitis

    phase 2 small molecule completed

    1 trial
  41. Oral Encochleated Amphotericin B (CAMB)

    Matinas BioPharma Holdings

    Acute Myeloid Leukemia

    phase 2 small molecule terminated

    1 trial
  42. Oral Ifetroban

    CUMBERLAND PHARMACEUTICALS INC

    Scleroderma, Diffuse

    phase 2 small molecule active

    1 trial
  43. Oral Insulin

    ORAMED PHARMACEUTICALS INC.

    Non-Alcoholic Steatohepatitis (NASH)

    phase 2 mab completed

    1 trial
  44. Oral MRT-2359

    Monte Rosa Therapeutics

    NSCLC

    phase 2 small molecule active

    1 trial
  45. Oral Naltrexone

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 2 small molecule completed

    1 trial
  46. Oral arsenic trioxide

    The University of Hong Kong

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  47. Oral hexavalent reassortant rotavirus attenuated live vaccine

    Sinovac Research and Development Co.,

    Rotavirus Gastroenteritis

    phase 2 mab active

    2 trials
  48. Oral levetiracetam

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Neonatal Seizures

    phase 2 small molecule terminated

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Data attribution: Data sources · All pipeline programs