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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 93 of 151

  1. Non-invasive ventilation

    United Therapeutics Europe Ltd

    Amyotrophic Lateral Sclerosis (ALS)

    phase 2 other active

    1 trial

  2. Normix compresse rivestite con film for substance use disorder

    Fondazione Telethon ETS

    substance use disorder

    phase 2 small molecule active

    1 trial

  3. Norovirus Bivalent VLP Vaccine

    Takeda

    Norovirus Prevention

    phase 2 mab completed

    1 trial

  4. Norovirus Bivalent Vaccine

    Takeda

    Prevention From Norovirus Infection

    phase 2 mab completed

    1 trial

  5. Norovirus GI.1/GII.4 Bivalent VLP Vaccine

    Takeda

    Norovirus

    phase 2 mab completed

    1 trial

  6. Norwalk VLP vaccine

    Takeda

    Acute Gastroenteritis

    phase 2 mab completed

    1 trial

  7. Not the same excipients as Test, Balinatunfib

    Sanofi-aventis Healthcare Pty Ltd

    Colitis Ulcerative

    phase 2 small molecule active

    1 trial

  8. Novo Nordisk GlucaGen®

    Xeris Biopharma Holdings

    Hypoglycemia

    phase 2 small molecule completed

    1 trial

  9. NurOwn (MSC-NTF cells)

    BRAINSTORM CELL THERAPEUTICS INC.

    Multiple Sclerosis, Chronic Progressive

    phase 2 mab completed

    1 trial

  10. OBG PED-001

    KIORA PHARMACEUTICALS INC

    Persistent Corneal Epithelial Defect

    phase 2 small molecule completed

    1 trial

  11. OBINUTUZUMAB, Zanubrutinib

    BeiGene

    Relapsed/Refractory Follicular Lymphoma

    phase 2 small molecule active

    1 trial

  12. OCTREOTIDE ACETATE, Paltusotine tablets

    Lacuna Pharma Pty Ltd

    Carcinoid Syndrome

    phase 2 small molecule active

    1 trial

  13. OD-07656

    Odyssey Therapeutics

    Ulcerative Colitis (UC)

    phase 2 small molecule active

    1 trial

  14. OD-07656-201

    Odyssey Therapeutics

    Moderately to Severely Active Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  15. OGX-011

    United Therapeutics Europe Ltd

    Prostate Cancer

    phase 2 mab completed

    1 trial

  16. OKI-179 + binimetinib

    OnKure Therapeutics

    RAS Mutation

    phase 2 small molecule completed

    1 trial

  17. OLAPARIB, BEVACIZUMAB

    The George Institute

    Advanced FIGO Stage III‐IV High Grade Serous or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer

    phase 2 small molecule active

    1 trial

  18. OMC and pseudo-SDT

    The First People's Hospital of Lianyungang

    Peripheral Arterial Disease

    phase 2 other completed

    1 trial

  19. OMEPRAZOLE , ACETYLSALICYLIC ACID

    The George Institute

    Colorectal cancer

    phase 2 small molecule active

    1 trial

  20. OMP-59R5

    Mereo BioPharma Group plc

    Stage IV Small Cell Lung Cancer

    phase 2 small molecule terminated

    1 trial

  21. OMP-59R5

    Mereo BioPharma Group plc

    Stage IV Pancreatic Cancer

    phase 2 small molecule completed

    1 trial

  22. OMTX705-004

    Lacuna Pharma Pty Ltd

    Advanced/metastatic colorectal cancer

    phase 2 small molecule active

    1 trial

  23. OMTX705-005

    Lacuna Pharma Pty Ltd

    Advanced/Metastatic Non-squamous Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  24. ONC201

    Jazz Pharmaceuticals Ireland Limited

    Meningioma

    phase 2 small molecule terminated

    1 trial

  25. ONC201

    Jazz Pharmaceuticals Ireland Limited

    Multiple Myeloma

    phase 2 small molecule terminated

    1 trial

  26. ONC201

    Jazz Pharmaceuticals Ireland Limited

    Diffuse Intrinsic Pontine Glioma

    phase 2 small molecule active

    1 trial

  27. ONC201

    Jazz Pharmaceuticals Ireland Limited

    Advanced Glioblastoma

    phase 2 small molecule terminated

    1 trial

  28. ONC201, Paxalisib

    AXIM BIOTECHNOLOGIES, INC.

    Diffuse Midline Gliomas (DMGs) including Diffuse Intrinsic Pontine Gliomas (DIPGs)

    phase 2 small molecule active

    1 trial

  29. ONC206

    Jazz Pharmaceuticals Ireland Limited

    Advanced Pheochromocytoma and Paraganglioma

    phase 2 small molecule active

    1 trial

  30. OND-PR002 and MPh-IR

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 2 small molecule completed

    1 trial

  31. ONO-4578

    Ono Pharmaceutical Co.,

    Colorectal Cancer

    phase 2 small molecule active

    1 trial

  32. ONO-4578-10

    Lacuna Pharma Pty Ltd

    PD-L1 positive advanced colorectal cancer

    phase 2 small molecule active

    1 trial

  33. OP-1250

    Olema Pharmaceuticals

    Hormone Receptor Positive Breast Carcinoma

    phase 2 small molecule completed

    1 trial

  34. OPC-34712

    Otsuka Beijing Research Institute

    Schizophrenia

    phase 2 small molecule completed

    1 trial

  35. OPDIVO 10 mg/mL concentrate for solution for infusion.

    Ningbo Cancer Hospital

    Early stage triple negative breast cancer

    phase 2 small molecule active

    1 trial

  36. OPDIVO 10 mg/mL concentrate for solution for infusion.

    The George Institute

    Relapsing/Refractory ALK+ Anaplastic Large cell Lymphoma

    phase 2 small molecule active

    1 trial

  37. OPDIVO for Unresectable locally advanced o…

    Tour Hekla

    Unresectable locally advanced or metastatic urothelial cancer

    phase 2 small molecule active

    1 trial

  38. OPDIVO for advanced or metastatic gastrooe…

    Fondazione Telethon ETS

    advanced or metastatic gastrooesophageal carcinoma HER2 negative and ARID1A mutated

    phase 2 small molecule active

    1 trial

  39. OPM-101

    Chongqing Precision Biotech Co., Ltd

    Advanced Melanoma

    phase 2 small molecule active

    1 trial

  40. OPRX-106

    Protalix BioTherapeutics

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  41. ORI2025-16

    The George Institute

    Colon cancer

    phase 2 small molecule active

    1 trial

  42. ORIC-114

    Topiloric/Uriadec

    Solid Tumors

    phase 2 small molecule active

    1 trial

  43. ORIC-114

    Topiloric/Uriadec

    Solid Tumors

    phase 2 small molecule active

    1 trial

  44. ORKA-001

    Oruka Therapeutics

    Plaque Psoriasis

    phase 2 small molecule active

    2 trials

  45. ORKA-001 Induction Dose

    Oruka Therapeutics

    Plaque Psoriasis

    phase 2 small molecule active

    1 trial

  46. ORKA-001, Placebo for ORKA-001

    Oruka Therapeutics

    Moderate-to-Severe Plaque Psoriasis

    phase 2 small molecule active

    1 trial

  47. ORKA-002

    Oruka Therapeutics

    Plaque Psoriasis

    phase 2 small molecule active

    1 trial

  48. ORMD 0801

    ORAMED PHARMACEUTICALS INC.

    Brittle Type I Diabetes Mellitus

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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