Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    HER2 Amplified Breast Cancer

    phase 2 small molecule completed

    1 trial
  2. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Advanced Breast Cancer

    phase 2 small molecule completed

    1 trial
  3. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Breast Cancer

    phase 2 small molecule completed

    8 trials
  4. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Early-stage Breast Cancer

    phase 2 small molecule active

    1 trial
  5. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    GastroEsophageal Cancer

    phase 2 small molecule active

    1 trial
  6. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Early Stage HER2+ Breast Cancer

    phase 2 small molecule completed

    1 trial
  7. Neratinib

    PUMA BIOTECHNOLOGY, INC.

    Anatomic Stage I Breast Cancer

    phase 2 small molecule active

    1 trial
  8. NestaCell®

    Vera Therapeutics

    COVID-19 Pneumonia

    phase 2 mab completed

    1 trial
  9. Neu2000KWL

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Stroke

    phase 2 small molecule completed

    1 trial
  10. Neulasta 6 mg solution for injection

    Istituto Gentili S.r.l.

    Severe chronic neutropenia (SCN)

    phase 2 small molecule active

    1 trial
  11. NeuroEPO

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Parkinson Disease

    phase 2 small molecule completed

    1 trial
  12. NicVAX

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 mab completed

    1 trial
  13. NicVAX conjugate vaccine

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 mab completed

    1 trial
  14. Nicotine 0 mg/mL

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine

    phase 2 small molecule completed

    1 trial
  15. Nicotine Patch

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 2 small molecule completed

    2 trials
  16. Nicotine gum and lozenge

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 small molecule completed

    1 trial
  17. Nicotine replacement

    BRIGHT MINDS BIOSCIENCES INC.

    Cardiovascular Disease

    phase 2 small molecule completed

    1 trial
  18. Nilotinib followed by treatment-free

    Novartis Pharmaceuticals

    Chronic Myelogenous Leukemia

    phase 2 small molecule completed

    1 trial
  19. Nimodipine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial
  20. Nimotuzumab

    Chinese University of Hong Kong

    Esophageal Cancer

    phase 2 small molecule completed

    1 trial
  21. Nimotuzumab

    The First People's Hospital of Lianyungang

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  22. Nimotuzumab

    The First People's Hospital of Lianyungang

    Esophageal Neoplasms

    phase 2 small molecule active

    1 trial
  23. Nimotuzumab + SHR-1210

    The First People's Hospital of Lianyungang

    Esophageal Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  24. Nimotuzumab combined with chemoradiotherapy

    The First People's Hospital of Lianyungang

    Pancreatic Cancer Non-resectable

    phase 2 small molecule active

    1 trial
  25. Ninlaro

    Takeda

    Immune Thrombocytopenia

    phase 2 small molecule terminated

    1 trial
  26. Nintedanib,Dextromethorphan

    The First People's Hospital of Lianyungang

    Idiopathic Pulmonary Fibrosis (IPF)

    phase 2 small molecule active

    1 trial
  27. Niraparib

    Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    Platinum-resistant Recurrent Clear Cell Ovarian Cancer

    phase 2 small molecule completed

    1 trial
  28. Niraparib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Ovarian Cancer

    phase 2 small molecule active

    1 trial
  29. Niraparib

    Takeda

    Efficacy

    phase 2 small molecule active

    1 trial
  30. Niraparib

    Takeda

    Ovarian Cancer

    phase 2 small molecule completed

    2 trials
  31. Niraparib-Bevacizumab

    Takeda

    Platinum-sensitive Recurrent Ovarian Cancer Patients Previously Treated With a PARP Inhibitor

    phase 2 small molecule active

    1 trial
  32. Nitric Oxide

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pressure Ulcer

    phase 2 small molecule active

    1 trial
  33. Nitrofurazone Group 1

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule active

    1 trial
  34. Nitrous oxide

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 2 small molecule completed

    1 trial
  35. Nivolumab

    Bristol-Myers Squibb

    Prostate Cancer

    phase 2 mab completed

    1 trial
  36. Nivolumab

    Takeda

    Relapsed Multiple Myeloma

    phase 2 small molecule terminated

    1 trial
  37. Nivolumab

    Atrium Therapeutics

    Multiple Myeloma

    phase 2 small molecule active

    1 trial
  38. Nivolumab

    Mereo BioPharma Group plc

    Ovarian Cancer

    phase 2 small molecule active

    1 trial
  39. Nivolumab

    Nektar Therapeutics UK Limited

    Ependymoma

    phase 2 mab terminated

    1 trial
  40. Nivolumab

    Bristol-Myers Squibb

    Hepatocellular Carcinoma

    phase 2 mab completed

    1 trial
  41. Nivolumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Advanced Biliary Tract Cancer(BTC)

    phase 2 small molecule active

    1 trial
  42. Nivolumab

    Adaptive Biotechnologies Corp

    Bladder Cancer

    phase 2 small molecule completed

    1 trial
  43. Nivolumab

    United Therapeutics Europe Ltd

    Metastatic Uveal Melanoma

    phase 2 small molecule completed

    1 trial
  44. Nivolumab & Ipilimumab

    The First People's Hospital of Lianyungang

    Lung Cancer - Non Small Cell

    phase 2 small molecule active

    1 trial
  45. Nivolumab Injection [Opdivo]

    The First People's Hospital of Lianyungang

    Neoplasms

    phase 2 small molecule active

    1 trial
  46. NoV GI.1/GII.4 Bivalent VLP Vaccine

    Takeda

    Norovirus

    phase 2 mab completed

    1 trial
  47. NoV Placebo-matching Saline

    Takeda

    Healthy Volunteers

    phase 2 mab completed

    1 trial
  48. NoV Vaccine

    Takeda

    Healthy Volunteers

    phase 2 mab completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.