Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 86 of 151

  1. Marine active

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    "Hyperuricemia,Anserine"

    phase 2 small molecule active

    1 trial

  2. Match placebo to test product, Balinatunfib

    Sanofi-aventis Healthcare Pty Ltd

    Crohn's disease

    phase 2 small molecule active

    1 trial

  3. Matched Placebo

    Novo Nordisk A/S

    Mechanical allodynia

    phase 2 small molecule active

    1 trial

  4. Matched placebo for test product, Itepekimab

    Sanofi-aventis Healthcare Pty Ltd

    Respiratory tract diseases

    phase 2 small molecule active

    1 trial

  5. Matched placebo for test product, SAR444336

    Sanofi-aventis Healthcare Pty Ltd

    Digestive system diseases

    phase 2 small molecule active

    1 trial

  6. Matched, SAR444656

    Sanofi-aventis Healthcare Pty Ltd

    Dermatitis atopic

    phase 2 small molecule active

    1 trial

  7. Matches test product

    Bioprojet Pharma

    Essential tremor

    phase 2 small molecule active

    1 trial

  8. Matches test product

    Bioprojet Pharma

    Primary premature ejaculation

    phase 2 small molecule active

    1 trial

  9. Matching Placebo

    Cyclerion Therapeutics

    Diabetes Mellitus, Type 2

    phase 2 small molecule completed

    1 trial

  10. Matching film-coated placebo tablet

    Bioprojet Pharma

    Obsessive compulsive disorder

    phase 2 small molecule active

    1 trial

  11. Matching orodispersible placebo tablet

    Bioprojet Pharma

    Eosinophilic esophagitis

    phase 2 small molecule active

    1 trial

  12. Matching placebo

    BRIGHT MINDS BIOSCIENCES INC.

    Familial Dysautonomia

    phase 2 small molecule active

    1 trial

  13. Mavodelpar

    OnKure Therapeutics

    Primary Mitochondrial Myopathy

    phase 2 small molecule completed

    1 trial

  14. Mavrilimumab

    Kiniksa Pharmaceuticals International, plc

    COVID-19

    phase 2 small molecule completed

    3 trials

  15. Mazindol

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  16. Mebendazole

    Krystal Biotech Netherlands B.V.

    Pilomyxoid Astrocytoma

    phase 2 small molecule completed

    1 trial

  17. Mecasermin rinfabate

    Wuhan Createrna Science and Technology Co., Ltd

    Chronic Lung Disease

    phase 2 small molecule active

    1 trial

  18. Medical Collagen Membrane with MSC

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Wounds

    phase 2 other active

    1 trial

  19. Medtronic PrimeADVANCED Neurostimulator

    Rhythm Pharmaceuticals Netherlands B.V.

    Heart Failure

    phase 2 other completed

    1 trial

  20. Mekinist 0.5 mg film-coated tablets

    Disc Medicine

    Neurofibromatosis type 1

    phase 2 small molecule active

    1 trial

  21. Mektovi film-coated tablets for metastatic colorectal cancer wi…

    Disc Medicine

    metastatic colorectal cancer with a proven RAS mutation after failure of standard systemic treatment regimens including at least 5- FU/capecitabine-oxaliplatin and irinotecan based standard treatment (unless contra-indications for either oxaliplatin or irinotecan)

    phase 2 small molecule active

    1 trial

  22. Melperone HCl

    Lundbeck Australia Pty Ltd

    Parkinson's Disease

    phase 2 small molecule completed

    1 trial

  23. Melphalan

    Takeda

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  24. Melphalan

    Ultragenyx UK Limited

    Amyloidosis

    phase 2 small molecule completed

    1 trial

  25. Melphalan flufenamide (Melflufen)

    Chongqing Precision Biotech Co., Ltd

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  26. Memantine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  27. Memantine Oral Tablet

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Radiation Disease

    phase 2 small molecule active

    1 trial

  28. Memory Flexibility Training

    COGNITION THERAPEUTICS INC

    Major Depressive Disorder

    phase 2 other completed

    1 trial

  29. MenSCs transplantation

    The First People's Hospital of Lianyungang

    Type 1 Diabetes Mellitus

    phase 2 mab active

    1 trial

  30. Meningococcal Groups A and C and Haemophilus b Conjugate Vaccine (adjuvant-free)

    BRIGHT MINDS BIOSCIENCES INC.

    Meningitis

    phase 2 mab active

    1 trial

  31. Menstrual blood stem cells

    The First People's Hospital of Lianyungang

    Acute Lung Injury

    phase 2 small molecule active

    1 trial

  32. Merimepodib

    Vertex Pharmaceuticals (Australia) Pty.

    Hepatitis C

    phase 2 small molecule completed

    1 trial

  33. Meropenem-Vaborbactam

    Lacuna Pharma Pty Ltd

    Complicated Urinary Tract Infection (cUTI), Acute Pyelonephritis (AP)

    phase 2 small molecule active

    1 trial

  34. Mesenchymal Stromal Cells

    United Therapeutics Europe Ltd

    Corneal Ulcer

    phase 2 mab active

    1 trial

  35. Mesenchymal progenitor cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Knee Osteoarthritis

    phase 2 mab completed

    1 trial

  36. Mesenchymal stem cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hematopoietic Stem Cell Transplantation

    phase 2 mab active

    1 trial

  37. Mesenchymal stem cells

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chronic Graft-versus-host Disease

    phase 2 mab active

    1 trial

  38. Mesenchymal stem cells for Systemic Sclerosis

    Disc Medicine

    Systemic Sclerosis

    phase 2 small molecule active

    1 trial

  39. Mesenchymal stem cells from adipose tissue

    Lxo Ireland Designated Activity Company

    Critical Limb Ischemia

    phase 2 other completed

    1 trial

  40. Metformin

    United Therapeutics Europe Ltd

    C9orf72 Amyotrophic Lateral Sclerosis (ALS)

    phase 2 small molecule active

    1 trial

  41. Metformin

    United Therapeutics Europe Ltd

    Polycystic Kidney, Autosomal Dominant

    phase 2 small molecule completed

    1 trial

  42. Metformin + Standard of Care

    United Therapeutics Europe Ltd

    Focal Segmental Glomerulosclerosis

    phase 2 small molecule active

    1 trial

  43. Metformin Hydrochloride ER

    Atrium Therapeutics

    Sarcoma Metastatic

    phase 2 small molecule active

    1 trial

  44. Metformin Zentiva 500 mg Filmtabletten

    The George Institute

    Multidrug rezistant pulmonary tuberculosis

    phase 2 small molecule active

    1 trial

  45. Methadone

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  46. Methamphetamine

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Intoxication

    phase 2 small molecule active

    1 trial

  47. Methotrexate

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Primary Central Nervous System Lymphoma

    phase 2 small molecule active

    1 trial

  48. Methotrexate tablets

    The First People's Hospital of Lianyungang

    Solid Tumors

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.