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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 78 of 151

  1. LY2875358, ERLOTINIB

    Eli Lilly Co.

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  2. LY3454738

    Eli Lilly and Company

    Atopic Dermatitis

    phase 2 small molecule terminated

    1 trial

  3. LY3471851

    Nektar Therapeutics UK Limited

    Systemic Lupus Erythematosus

    phase 2 small molecule completed

    2 trials

  4. LY3471851

    Nektar Therapeutics UK Limited

    Colitis, Ulcerative

    phase 2 small molecule terminated

    1 trial

  5. LY3871801

    RIGEL PHARMACEUTICALS INC

    Rheumatoid Arthritis

    phase 2 small molecule completed

    1 trial

  6. LY4268989

    Eli Lilly and Company

    Ulcerative Colitis (UC)

    phase 2 small molecule active

    1 trial

  7. LZRSE-Col7A1 Engineered Autologous Epidermal Sheets

    ABEONA THERAPEUTICS INC.

    Epidermolysis Bullosa Dystrophica

    phase 2 mab completed

    1 trial

  8. Labetalol

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  9. Lactezin

    United Therapeutics Europe Ltd

    Hormonal Acne

    phase 2 other active

    1 trial

  10. Lactulose

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Constipation

    phase 2 small molecule completed

    1 trial

  11. Lacutamab

    Lacuna Pharma Pty Ltd

    Advanced T-Cell Lymphomas (TCL), i.e. Cutaneous T Cell Lymphomas (CTCL) CTCL subtypes under investigation: relapsed/refractory Sézary Syndrome (SS), stage IB to IV Mycosis Fungoides (MF).

    phase 2 small molecule active

    1 trial

  12. Ladarixin, Placebo to match Ladarixin

    Dompe' Farmaceutici S.p.A.

    Recent onset Type 1 Diabetes

    phase 2 small molecule active

    1 trial

  13. Laminectomy

    Biotech Pharmaceutical Co.,

    Acute Spinal Cord Injury

    phase 2 other active

    1 trial

  14. Lamivudina Aurovitas 300 mg comprimidos recubiertos con película EFG

    MEDA Pharma GmbH & Co. KG

    Mild Cognitive impairment due to Alzheimer Disease

    phase 2 small molecule active

    1 trial

  15. Lamotrigine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial

  16. Lanraplenib

    Lakefront Biotherapeutics NV

    Cutaneous Lupus Erythematosus

    phase 2 small molecule completed

    1 trial

  17. Lanraplenib

    Lakefront Biotherapeutics NV

    Sjogren's Syndrome

    phase 2 small molecule completed

    1 trial

  18. Lansoprazole

    Takeda

    Esophagitis

    phase 2 small molecule completed

    1 trial

  19. Lanthanum Polystyrene Sulphonate Powder

    The First People's Hospital of Lianyungang

    Hyperphosphatemia

    phase 2 small molecule active

    1 trial

  20. Lanthanum carbonate

    Takeda

    Chronic Kidney Disease

    phase 2 small molecule completed

    2 trials

  21. Lapaquistat acetate and fenofibrate

    Takeda

    Hyperlipidemias

    phase 2 small molecule completed

    1 trial

  22. Lapatinib

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 2 small molecule completed

    1 trial

  23. Laquinimod

    Teva Pharma GmbH

    Huntington's Disease

    phase 2 small molecule completed

    1 trial

  24. Laquinimod

    Teva Pharma GmbH

    Lupus Arthritis

    phase 2 small molecule completed

    1 trial

  25. Laquinimod

    Teva Pharma GmbH

    Lupus Nephritis

    phase 2 small molecule completed

    1 trial

  26. Laquinimod

    Teva Pharma GmbH

    Crohn's Disease

    phase 2 small molecule completed

    1 trial

  27. Laquinimod 0.6

    Teva Pharma GmbH

    Relapsing Multiple Sclerosis

    phase 2 small molecule terminated

    1 trial

  28. Larazotide Acetate

    Teva Pharma GmbH

    Celiac Disease

    phase 2 small molecule completed

    1 trial

  29. Lasofoxifene

    LIGAND PHARMACEUTICALS INC

    Bone Loss

    phase 2 small molecule completed

    1 trial

  30. Late immunity following single immunization with GA2 sporozoites (GACHA)

    Disc Medicine

    Falciparum malaria

    phase 2 other active

    1 trial

  31. Leflunomide

    Sanofi Pasteur

    Systemic Lupus Eythematosus (SLE)

    phase 2 small molecule completed

    1 trial

  32. Leflunomide CF for primary Sjögren's Syndrome

    Disc Medicine

    primary Sjögren's Syndrome

    phase 2 small molecule active

    1 trial

  33. Lemborexant

    BRIGHT MINDS BIOSCIENCES INC.

    Drug Interaction

    phase 2 small molecule completed

    1 trial

  34. Lenabasum 20 mg

    Corbus Pharmaceuticals Holdings

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial

  35. Lenalidomide

    Takeda

    Myeloma, Multiple

    phase 2 small molecule active

    1 trial

  36. Lenalidomide

    United Therapeutics Europe Ltd

    Recurrent Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial

  37. Lenalidomide

    The First People's Hospital of Lianyungang

    PTCL, NOS

    phase 2 small molecule active

    1 trial

  38. Lenalidomide [Leavdo®]

    Hospital Authority, Hong Kong

    Antibiotics-unresponsive MALT Lymphoma

    phase 2 small molecule active

    1 trial

  39. Lenalidomide and Gemcitabine (Dose level 11)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Peripheral T-cell Lymphomas (PTCL)

    phase 2 small molecule terminated

    1 trial

  40. Lenalidomide combined with G-CHOP (LO CHOP)

    The First People's Hospital of Lianyungang

    DLBCL - Diffuse Large B Cell Lymphoma

    phase 2 small molecule active

    1 trial

  41. Lenvatinib

    The First People's Hospital of Lianyungang

    Biliary Tract Cancer

    phase 2 small molecule active

    1 trial

  42. Lenvatinib

    United Therapeutics Europe Ltd

    Columnar Cell Variant Thyroid Gland Papillary Carcinoma

    phase 2 small molecule completed

    1 trial

  43. Lenvatinib

    Eisai Co.,

    Osteosarcoma

    phase 2 small molecule completed

    1 trial

  44. Lenvima 4 mg Oral Capsule

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial

  45. Letrozole

    United Therapeutics Europe Ltd

    Lymphangioleiomyomatosis

    phase 2 small molecule completed

    1 trial

  46. Letrozole

    United Therapeutics Europe Ltd

    Breast Cancer

    phase 2 small molecule completed

    1 trial

  47. Letrozole

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Uterine Cervical Neoplasms

    phase 2 small molecule active

    1 trial

  48. Leucovorin

    Cardiff Oncology

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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