Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Itepekimab (SAR440340)

    Regeneron UK Limited

    Bronchiectasis

    phase 2 small molecule completed

    1 trial
  2. Itepekimab, Matched placebo for test product

    Sanofi-aventis Healthcare Pty Ltd

    Bronchiectasis

    phase 2 small molecule active

    1 trial
  3. Ivacaftor

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Obstructive Pulmonary Disease

    phase 2 small molecule terminated

    1 trial
  4. Ivacaftor 150 MG

    Vertex Pharmaceuticals (Australia) Pty.

    Chronic Obstructive Pulmonary Disease

    phase 2 small molecule completed

    1 trial
  5. Ivacaftor 25 mg/75 mg

    Vertex Pharmaceuticals (Australia) Pty.

    Cystic Fibrosis

    phase 2 small molecule completed

    1 trial
  6. Ivaltinostat

    CG Oncology

    Metastatic Pancreatic Adenocarcinoma

    phase 2 small molecule active

    1 trial
  7. Ivonescimab

    Summit Therapeutics

    Endometrial Cancer

    phase 2 small molecule active

    1 trial
  8. Ivonescimab

    Summit Therapeutics

    Cutaneous Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  9. Ivonescimab

    Summit Therapeutics

    Thymus Carcinoma

    phase 2 mab active

    1 trial
  10. Ivonescimab

    Summit Therapeutics

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    2 trials
  11. Ivonescimab

    Summit Therapeutics

    Glioblastoma

    phase 2 small molecule active

    1 trial
  12. Ivonescimab

    Summit Therapeutics

    Leiomyosarcoma

    phase 2 small molecule active

    1 trial
  13. Ivonescimab

    Summit Therapeutics

    Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial
  14. Ivonescimab

    Summit Therapeutics

    Ivonescimab

    phase 2 small molecule active

    1 trial
  15. Ivonescimab

    Summit Therapeutics

    Metastatic Esophageal Adenocarcinoma

    phase 2 small molecule active

    1 trial
  16. Ivonescimab

    Summit Therapeutics

    Pleural Mesotheliomas

    phase 2 small molecule active

    1 trial
  17. Ivonescimab

    Summit Therapeutics

    Salivary Gland Cancer

    phase 2 small molecule active

    1 trial
  18. Ivonescimab

    Summit Therapeutics

    Biliary Tract Cancer

    phase 2 small molecule active

    1 trial
  19. Ivonescimab

    Summit Therapeutics

    Stomach Cancer Stage IV

    phase 2 small molecule active

    1 trial
  20. Ivonescimab

    Summit Therapeutics

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    3 trials
  21. Ivonescimab

    Summit Therapeutics

    TNBC

    phase 2 small molecule active

    1 trial
  22. Ivonescimab

    Summit Therapeutics

    Advanced Head and Neck Squamous Cell Carcinoma

    phase 2 mab active

    1 trial
  23. Ivonescimab 10 mg/kg

    Summit Therapeutics

    Extensive Stage Lung Small Cell Cancer

    phase 2 small molecule active

    1 trial
  24. Ivonescimab 20 mg/kg

    Hospital Authority, Hong Kong

    Nasopharyngeal Carcinoma (NPC)

    phase 2 small molecule active

    1 trial
  25. Ivonescimab Combined With Chemotherapy

    The First People's Hospital of Lianyungang

    Pretreated Pleural Mesothelioma

    phase 2 small molecule active

    1 trial
  26. Ivonescimab combined with TP

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head and Neck Squamous Cell Carcinoma

    phase 2 small molecule active

    1 trial
  27. Ivosidenib combined with venetoclax and azacitidine

    The First People's Hospital of Lianyungang

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  28. Ixabepilone Injection

    Allarity Therapeutics

    Metastatic Breast Cancer

    phase 2 small molecule terminated

    1 trial
  29. Ixazomib

    Takeda

    Multiple Myeloma

    phase 2 small molecule completed

    15 trials
  30. Ixazomib

    Takeda

    Triple-Negative Breast Cancer

    phase 2 small molecule terminated

    1 trial
  31. Ixazomib

    Takeda

    Smoldering Multiple Myeloma

    phase 2 small molecule completed

    1 trial
  32. Ixazomib

    Takeda

    Relapsed/Refractory Multiple Myeloma

    phase 2 small molecule terminated

    1 trial
  33. Ixazomib

    Takeda

    Newly Diagnosed Multiple Myeloma

    phase 2 small molecule terminated

    1 trial
  34. Ixazomib

    Takeda

    Myeloid Hematologic Malignancy

    phase 2 small molecule completed

    1 trial
  35. Ixazomib

    Takeda

    Mantle Cell Lymphoma

    phase 2 small molecule active

    2 trials
  36. Ixazomib

    Takeda

    Leukemia

    phase 2 small molecule terminated

    1 trial
  37. Ixazomib

    Takeda

    ALL, Childhood

    phase 2 small molecule active

    1 trial
  38. Ixazomib 1 MG

    Takeda

    Human Immunodeficiency Virus (HIV)

    phase 2 small molecule completed

    1 trial
  39. Ixazomib/Pomalidomide/Dexamethasone

    Takeda

    Multiple Myeloma

    phase 2 small molecule terminated

    1 trial
  40. J1I-MC-GZBU

    Eli Lilly Co.

    Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

    phase 2 small molecule active

    1 trial
  41. J1R-MC-GZFD

    Eli Lilly Co.

    Type 2 Diabetes

    phase 2 small molecule active

    1 trial
  42. J1S-MC-JP04

    Eli Lilly Co.

    Ewings Sarcoma

    phase 2 small molecule active

    1 trial
  43. J2R-MC-YAAD

    Eli Lilly Co.

    Nausea, Drug-Related Side Effects and Adverse Reactions, Vomiting, Neoplasms

    phase 2 small molecule active

    1 trial
  44. J2S-MC-GZMR

    Eli Lilly Co.

    Asthma

    phase 2 small molecule active

    1 trial
  45. J6E-MC-KWAN

    Eli Lilly Co.

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial
  46. JAB-21822

    Lacuna Pharma Pty Ltd

    advanced solid tumors with KRAS G12C mutation

    phase 2 small molecule active

    1 trial
  47. JADE101

    Jade Biosciences

    IgA Nephropathy

    phase 2 small molecule active

    1 trial
  48. JBT-101

    Corbus Pharmaceuticals Holdings

    Systemic Lupus Erythematosus

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.