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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 72 of 151

  1. Intervention A Fluoxetine Hydrochloride (HCl)

    Adaptive Biotechnologies Corp

    Post Traumatic Stress Disorder

    phase 2 small molecule active

    2 trials

  2. Intervention B Vilazodone Hydrochloride (HCl)

    Adaptive Biotechnologies Corp

    Post Traumatic Stress Disorder

    phase 2 small molecule active

    1 trial

  3. Intervention C Daridorexant

    Adaptive Biotechnologies Corp

    Post Traumatic Stress Disorder

    phase 2 small molecule active

    1 trial

  4. Intervention Condition

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 2 other completed

    1 trial

  5. Intervention D SLS-002

    Adaptive Biotechnologies Corp

    Post Traumatic Stress Disorder

    phase 2 small molecule on hold

    1 trial

  6. Intismeran autogene

    Merck KGaA, Darmstadt, Germany

    Malignant Melanoma

    phase 2 mab active

    1 trial

  7. Intraarterial infusion of autologous bone marrow cells

    Lxo Ireland Designated Activity Company

    Critical Limb Ischemia (CLI)

    phase 2 other completed

    2 trials

  8. Intracavernosal administration of autologous ADRC

    The First People's Hospital of Lianyungang

    Erectile Dysfunction

    phase 2 other completed

    1 trial

  9. Intracoronary infusion of autologous bone marrow cells

    Lxo Ireland Designated Activity Company

    Dilated Cardiomyopathy

    phase 2 other completed

    1 trial

  10. Intranasal Oxytocin

    United Therapeutics Europe Ltd

    Autism Spectrum Disorder

    phase 2 small molecule completed

    1 trial

  11. Intravenous Gemini

    REVELATION BIOSCIENCES, INC.

    Renal Insufficiency, Chronic

    phase 2 small molecule completed

    1 trial

  12. Intravenous administration of 1 million of MSC

    Lxo Ireland Designated Activity Company

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule completed

    1 trial

  13. Intravenous esketamine using Dixon's up-and-down sequential method

    The First People's Hospital of Lianyungang

    Hepatic Neoplasm

    phase 2 small molecule active

    1 trial

  14. Intraventricular Pemetrexed

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Leptomeningeal Metastasis

    phase 2 small molecule active

    1 trial

  15. Intravitreal Aflibercept Injection

    Regeneron UK Limited

    Age-Related Macular Degeneration

    phase 2 small molecule completed

    2 trials

  16. Intravitreal Aflibercept Injection

    Regeneron UK Limited

    Diabetic Macular Edema

    phase 2 small molecule completed

    1 trial

  17. Intravitreal Aflibercept Injection

    Regeneron UK Limited

    Central Serous Chorioretinopathy

    phase 2 small molecule completed

    1 trial

  18. Intravitreal Aflibercept Injection

    Regeneron UK Limited

    Central Retinal Vein Occlusion

    phase 2 small molecule completed

    1 trial

  19. Intravitreal injection of KH902

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Neovascular Age-related Macular Degeneration

    phase 2 mab completed

    1 trial

  20. Investigational new drug company code: BGS649

    Mereo BioPharma Group plc

    Obese Hypogonadotropic Hypogonadism

    phase 2 small molecule terminated

    1 trial

  21. Iodine-124

    United Therapeutics Europe Ltd

    Thyroid Cancer

    phase 2 small molecule active

    1 trial

  22. Iomab-B

    Actinium Pharmaceuticals

    Non Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial

  23. Iopofosine I 131 single dose

    Cellectar Biosciences

    Waldenstrom Macroglobulinemia

    phase 2 small molecule active

    1 trial

  24. Iparomlimab and Tuvonralimab Injection (QL1706)

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma

    phase 2 small molecule active

    1 trial

  25. Iparomlimab and Tuvonralimab Injection (QL1706)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cholangiocarcinoma

    phase 2 small molecule active

    1 trial

  26. Iparomlimab and Tuvonralimab Injection in combination with TFOX

    The First People's Hospital of Lianyungang

    Gastric or Gastroesophageal Junction Adenocarcinoma

    phase 2 small molecule active

    1 trial

  27. Iparomlimab and Tuvonralimab combined with lenvatinib and SOX

    The First People's Hospital of Lianyungang

    Gastric or Gastroesophageal Junction Adenocarcinoma

    phase 2 small molecule active

    1 trial

  28. Iparomlimab/Tuvonralimab

    The First People's Hospital of Lianyungang

    Recurrent Ovarian Cancer

    phase 2 small molecule active

    1 trial

  29. Iparomlimab/Tuvonralimab

    Chinese University of Hong Kong

    LOCALLY ADVANCED CERVICAL CANCERS

    phase 2 small molecule active

    1 trial

  30. Ipilimumab

    United Therapeutics Europe Ltd

    BCLC Stage B Hepatocellular Carcinoma

    phase 2 mab terminated

    1 trial

  31. Ipilimumab

    United Therapeutics Europe Ltd

    Locally Advanced Clear Cell Renal Cell Carcinoma

    phase 2 mab active

    1 trial

  32. Iptacopan

    Novartis Pharmaceuticals

    Immune Thrombocytopenia (ITP)

    phase 2 small molecule terminated

    1 trial

  33. Irinotecan

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial

  34. Irinotecan Accord 20 mg/ml concentraat voor oplossing voor infusie

    Disc Medicine

    Gastric peritoneal metastases

    phase 2 small molecule active

    1 trial

  35. Irinotecan Liposome

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    1 trial

  36. Irofulven

    Allarity Therapeutics

    Metastatic Castration-Resistant Prostate Cancer Patients

    phase 2 small molecule completed

    1 trial

  37. Irosustat

    United Therapeutics Europe Ltd

    Breast Neoplasms

    phase 2 small molecule terminated

    1 trial

  38. Isatuximab

    Sanofi Pasteur

    Relapsed/Refractory Multiple Myeloma

    phase 2 small molecule active

    1 trial

  39. Isis 420915/GSK 299872

    IONIS PHARMACEUTICALS INC

    Amyloidosis

    phase 2 small molecule terminated

    1 trial

  40. Islet transplantation with Tegoprubart (AT-1501) immunosupression-based therapy

    Eledon Pharmaceuticals

    Type 1 Diabetes Mellitus

    phase 2 small molecule active

    1 trial

  41. Isosorbide Mononitrate

    United Therapeutics Europe Ltd

    Kidney Injury

    phase 2 small molecule terminated

    1 trial

  42. Isradipine

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid Dependence

    phase 2 small molecule completed

    1 trial

  43. Istaroxime

    WINDTREE THERAPEUTICS INC /DE/

    Cardiogenic Shock

    phase 2 small molecule active

    2 trials

  44. Istaroxime, LActose

    WINDTREE THERAPEUTICS INC /DE/

    Cardiogenic Shock

    phase 2 small molecule active

    1 trial

  45. Itacitinib

    Pari Pharma GmbH

    Adults patients having non severe HLH

    phase 2 small molecule active

    1 trial

  46. Itacitinib, placebo of itacitinib 100mg

    Pari Pharma GmbH

    Patients with newly or active diffuse Systemic sclerosis (SSc) at the time of screening

    phase 2 small molecule active

    1 trial

  47. Itepekimab

    Sanofi-aventis Healthcare Pty Ltd

    Chronic Obstructive Pulmonary Disease

    phase 2 small molecule active

    1 trial

  48. Itepekimab (SAR440340)

    Regeneron UK Limited

    Chronic Rhinosinusitis Without Nasal Polyps

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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