Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Immune Globulin Intravenous (IVIG)

    BRIGHT MINDS BIOSCIENCES INC.

    Sickle Cell Disease

    phase 2 small molecule completed

    1 trial
  2. Immunization with P. vivax irradiated sporozoites

    BRIGHT MINDS BIOSCIENCES INC.

    Malaria

    phase 2 mab completed

    1 trial
  3. Immunological Agent

    The First People's Hospital of Lianyungang

    Lung Cancer Metastatic

    phase 2 small molecule active

    1 trial
  4. Immunomodulatory DC vaccines to target prostate cancer

    Shenzhen Second People's Hospital

    Prostate Cancer Indications

    phase 2 mab active

    1 trial
  5. Immunotherapy combined with chemotherapy

    The First People's Hospital of Lianyungang

    Rectal Adenocarcinoma

    phase 2 small molecule active

    1 trial
  6. Impedance Threshold Device

    United Therapeutics Europe Ltd

    Hypotension

    phase 2 other completed

    1 trial
  7. Imsidolimab

    Vanda Pharmaceuticals Netherlands B.V.

    Ichthyosis

    phase 2 small molecule terminated

    1 trial
  8. Imsidolimab

    Vanda Pharmaceuticals Netherlands B.V.

    Acneiform Eruptions

    phase 2 mab terminated

    1 trial
  9. Imsidolimab

    Vanda Pharmaceuticals Netherlands B.V.

    Generalized Pustular Psoriasis

    phase 2 mab completed

    1 trial
  10. Imsidolimab

    Vanda Pharmaceuticals Netherlands B.V.

    Acne Vulgaris

    phase 2 small molecule completed

    1 trial
  11. Imsidolimab

    Vanda Pharmaceuticals Netherlands B.V.

    Palmoplantar Pustulosis

    phase 2 mab completed

    1 trial
  12. Imsidolimab

    Vanda Pharmaceuticals Netherlands B.V.

    Hidradenitis Suppurativa

    phase 2 mab completed

    1 trial
  13. Imx-110

    Immix Biopharma

    Solid Tumor, Adult

    phase 2 small molecule active

    1 trial
  14. Inactivated Poliomyelitis vaccine (IMOVAX)

    Sanofi Pasteur

    Poliomyelitis

    phase 2 mab completed

    1 trial
  15. Inactive Marijuana (0% THC)

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Smoking

    phase 2 small molecule completed

    1 trial
  16. Inaxaplin

    Vertex Pharmaceuticals (Australia) Pty.

    Proteinuric Kidney Disease

    phase 2 small molecule active

    1 trial
  17. Indapamide

    Alnylam Netherlands B.V.

    Hypertension

    phase 2 small molecule completed

    1 trial
  18. Indibulin

    Alaunos Therapeutics

    Metastatic Breast Cancer

    phase 2 small molecule active

    1 trial
  19. Indigo naturalis ointment

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Psoriasis

    phase 2 small molecule completed

    1 trial
  20. Induction Therapy

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Splenic B-cell Lymphoma/Leukaemia With Prominent Nucleoli,SBLPN

    phase 2 small molecule active

    1 trial
  21. Induction of neo-antigen specific T cells by... for Ovarian cancer

    Disc Medicine

    Ovarian cancer

    phase 2 other active

    1 trial
  22. Induction therapy of GP(Pomalidomide+Obinutuzumab)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Indolent Lymphoma

    phase 2 small molecule active

    1 trial
  23. Inetetamab

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule active

    1 trial
  24. Infigratinib

    BridgeBio Oncology Therapeutics

    Achondroplasia

    phase 2 small molecule active

    1 trial
  25. Infigratinib

    BridgeBio Oncology Therapeutics

    Hypochondroplasia

    phase 2 small molecule active

    1 trial
  26. Infigratinib 0.016 mg/kg

    BridgeBio Oncology Therapeutics

    Achondroplasia

    phase 2 small molecule completed

    1 trial
  27. Infigratinib is provided as a single dose of minitablets for oral administration

    BridgeBio Oncology Therapeutics

    Achondroplasia

    phase 2 small molecule active

    1 trial
  28. Infusion of MSC

    Lxo Ireland Designated Activity Company

    Discordant Immunological Response in HIV Infected Subjects

    phase 2 small molecule completed

    1 trial
  29. Infusion of autologous mononuclear bone marrow cells

    Lxo Ireland Designated Activity Company

    Idiopathic Dilated Cardiomyopathy

    phase 2 small molecule terminated

    1 trial
  30. Infusion of mesenchymal stem cells from adipose tissue

    Lxo Ireland Designated Activity Company

    Faecal Incontinence

    phase 2 small molecule completed

    1 trial
  31. Inhaled Treprostinil

    United Therapeutics Europe Ltd

    Sarcoidosis

    phase 2 small molecule completed

    1 trial
  32. Inhaled Treprostinil (Tyvaso Nebulizer)

    United Therapeutics Europe Ltd

    COPD (Chronic Obstructive Pulmonary Disease)

    phase 2 small molecule active

    1 trial
  33. Iniparib

    Sanofi Pasteur

    Breast Cancer, Metastatic

    phase 2 small molecule completed

    1 trial
  34. Injectable suspension of allogeneic adult mesenchymal stem cells

    Lxo Ireland Designated Activity Company

    Hidradenitis Suppurativa

    phase 2 mab active

    1 trial
  35. Injection of IAH0968+Gemcitabine+Cisplatin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    HER2 Gene Mutation

    phase 2 other active

    1 trial
  36. Injection of humanized nerve growth factor (NGF) antibody

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Cancer Pain

    phase 2 small molecule active

    1 trial
  37. Inotuzumab Ozogamicin±Donor Lymphocyte Infusion

    The First People's Hospital of Lianyungang

    Leukemia, Lymphocytic, Acute

    phase 2 small molecule active

    1 trial
  38. Inotuzumab ozogamicin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Acute Lymphocytic Leukemia

    phase 2 small molecule active

    1 trial
  39. Insulin

    United Therapeutics Europe Ltd

    Multiple Sclerosis, Relapsing-Remitting

    phase 2 small molecule completed

    1 trial
  40. Insulin

    United Therapeutics Europe Ltd

    Acute Stroke

    phase 2 small molecule completed

    1 trial
  41. Insulin lispro

    HALOZYME THERAPEUTICS, INC.

    Diabetes Mellitus, Type 1

    phase 2 small molecule completed

    2 trials
  42. Insulin lispro

    HALOZYME THERAPEUTICS, INC.

    Diabetes Mellitus, Type II

    phase 2 small molecule completed

    1 trial
  43. Intensive Intraperitoneal Therapy in Advanced Ovarian Cancer

    The George Institute

    Ovarian Cancer

    phase 2 other active

    1 trial
  44. Interactive injection and sexual risk intervention

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 2 other completed

    1 trial
  45. Interferon Beta-1B

    The University of Hong Kong

    COVID

    phase 2 small molecule completed

    1 trial
  46. Interleukin-7 and Chemokine (C-C Motif) Ligand 19-expressing CD19-CAR-T cells

    The First People's Hospital of Lianyungang

    B Cell Lymphoma

    phase 2 mab active

    1 trial
  47. Intermittent Oral Naltrexone

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine

    phase 2 small molecule completed

    1 trial
  48. Intermittent PD-1/PD-L1 ICI + VEGFR-TKI

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Renal Cell Carcinoma (RCC)

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.