Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 70 of 151
  1. IVPT

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Use Disorders

    phase 2 other completed

    1 trial
  2. IW-1701

    Cyclerion Therapeutics

    Sickle Cell Disease

    phase 2 small molecule completed

    1 trial
  3. IW-1973

    Cyclerion Therapeutics

    Diabetes Mellitus, Type 2

    phase 2 small molecule completed

    1 trial
  4. IW-1973

    Akebia Europe Limited

    Type 2 Diabetes Mellitus With Diabetic Nephropathy

    phase 2 small molecule completed

    1 trial
  5. IW-1973

    Akebia Europe Limited

    Heart Failure With Preserved Ejection Fraction

    phase 2 small molecule completed

    1 trial
  6. IW-3300 rectal foam

    IRONWOOD PHARMACEUTICALS INC

    Interstitial Cystitis

    phase 2 small molecule terminated

    1 trial
  7. IW-3718

    IRONWOOD PHARMACEUTICALS INC

    Gastroesophageal Reflux

    phase 2 small molecule completed

    1 trial
  8. IW-3718

    IRONWOOD PHARMACEUTICALS INC

    Gastroesophageal Reflux Disease

    phase 2 small molecule completed

    1 trial
  9. IW-6118

    IRONWOOD PHARMACEUTICALS INC

    Healthy

    phase 2 small molecule completed

    1 trial
  10. IW-9179

    IRONWOOD PHARMACEUTICALS INC

    Dyspepsia

    phase 2 small molecule terminated

    1 trial
  11. IW-9179

    IRONWOOD PHARMACEUTICALS INC

    Diabetic Gastroparesis

    phase 2 small molecule completed

    1 trial
  12. IXAZOMIB

    Takeda

    Follicular Lymphoma

    phase 2 small molecule completed

    1 trial
  13. Ibezapolstat

    Acurx Pharmaceuticals

    Clostridium Difficile Infection

    phase 2 small molecule completed

    1 trial
  14. Ibezapolstat

    Acurx Pharmaceuticals

    Clostridium Difficile Infection Recurrence

    phase 2 small molecule active

    1 trial
  15. Ibrutinib

    Karyopharm Therapeutics Inc

    Lymphoma

    phase 2 small molecule active

    1 trial
  16. Ibrutinib

    United Therapeutics Europe Ltd

    Asymptomatic COVID-19 Infection Laboratory-Confirmed

    phase 2 small molecule terminated

    1 trial
  17. Ibrutinib 560 mg

    United Therapeutics Europe Ltd

    Mantle Cell Lymphoma

    phase 2 small molecule active

    1 trial
  18. Ibudilast

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine Dependence

    phase 2 small molecule completed

    1 trial
  19. Ibuprofen

    United Therapeutics Europe Ltd

    Tonsillectomy

    phase 2 small molecule completed

    1 trial
  20. Ibuprofen-PC

    Protalix BioTherapeutics

    Osteoarthritis

    phase 2 small molecule completed

    1 trial
  21. Iclusig 15 mg film-coated tablets

    Ningbo Cancer Hospital

    Chronic myelogenous leukemia

    phase 2 small molecule active

    1 trial
  22. Icotinib

    The First People's Hospital of Lianyungang

    Esophageal Cancer

    phase 2 small molecule active

    1 trial
  23. Icotinib

    The First People's Hospital of Lianyungang

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  24. Idasanutlin

    Hoffmann-La Roche

    Follicular Lymphoma

    phase 2 small molecule terminated

    1 trial
  25. Idefirix 11 mg powder for concentrate for solution for infusion

    Disc Medicine

    neuromyelitis optica spectrum disorder, devic disease

    phase 2 small molecule active

    1 trial
  26. Idursulfase IT (1 mg)

    Takeda

    Hunter Syndrome

    phase 2 small molecule completed

    1 trial
  27. Ifetroban

    CUMBERLAND PHARMACEUTICALS INC

    Portal Hypertension

    phase 2 small molecule completed

    1 trial
  28. Ifetroban

    CUMBERLAND PHARMACEUTICALS INC

    Duchenne Muscular Dystrophy Cardiomyopathy

    phase 2 small molecule completed

    1 trial
  29. Ifetroban Injection

    CUMBERLAND PHARMACEUTICALS INC

    Hepatorenal Syndrome

    phase 2 small molecule completed

    1 trial
  30. Ifetroban Oral Capsule

    CUMBERLAND PHARMACEUTICALS INC

    Asthma, Aspirin-Induced

    phase 2 small molecule completed

    1 trial
  31. Ifetroban Sodium

    CUMBERLAND PHARMACEUTICALS INC

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    1 trial
  32. Ifetroban Sodium

    CUMBERLAND PHARMACEUTICALS INC

    Cardiovascular Diseases

    phase 2 small molecule completed

    1 trial
  33. Ifetroban Sodium

    CUMBERLAND PHARMACEUTICALS INC

    Malignant Solid Tumor

    phase 2 small molecule active

    1 trial
  34. Ifetroban, Oral Capsule

    CUMBERLAND PHARMACEUTICALS INC

    Aspirin Exacerbated Respiratory Disease (AERD)

    phase 2 small molecule completed

    1 trial
  35. Ifinatamab Deruxtecan

    Merck Sharp and Dohme

    Esophageal squamous cell carcinoma

    phase 2 small molecule active

    1 trial
  36. Ifinatamab deruxtecan

    Daiichi Sankyo

    Recurrent or Metastatic Solid Tumors (endometrial cancer (EC); head and neck squamous cell carcinoma (HNSCC); pancreatic ductal adenocarcinoma (PDAC); colorectal cancer (CRC); hepatocellular carcinoma (HCC); adenocarcinoma of esophagus, gastroesophageal junction, and stomach (Ad-Eso/GEJ/gastric); urothelial carcinoma (UC); ovarian cancer (OVC); cervical cancer (CC); biliary tract cancer (BTC); human epidermal growth factor 2 (HER2)-low breast cancer (BC); HER2 immunohistochemistry (IHC) 0 BC; and cutaneous melanoma)

    phase 2 small molecule active

    1 trial
  37. Ifinatamab deruxtecan

    Daiichi Sankyo

    Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCLC)

    phase 2 small molecule active

    1 trial
  38. Iguratimod

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    ITP

    phase 2 small molecule active

    1 trial
  39. IkT-001Pro

    Inhibikase Therapeutics

    Pulmonary Arterial Hypertension (PAH)

    phase 2 small molecule terminated

    1 trial
  40. Ilaprazole

    Takeda

    Esophagitis

    phase 2 small molecule completed

    1 trial
  41. Iloperidone

    Vanda Pharmaceuticals Netherlands B.V.

    Parkinson Disease Psychosis

    phase 2 small molecule terminated

    1 trial
  42. Iloperidone crystalline formulation

    Vanda Pharmaceuticals Netherlands B.V.

    Schizophrenia

    phase 2 small molecule completed

    1 trial
  43. Imatinib

    The First People's Hospital of Lianyungang

    Progression-free Survival

    phase 2 small molecule active

    1 trial
  44. Imatinib Mesylate

    United Therapeutics Europe Ltd

    Pulmonary Arterial Hypertension

    phase 2 small molecule active

    1 trial
  45. Imdusiran

    Arbutus Biopharma Corp

    Hepatitis B, Chronic

    phase 2 small molecule terminated

    1 trial
  46. Imdusiran (AB-729)

    Arbutus Biopharma Corp

    Chronic Hepatitis B

    phase 2 small molecule active

    1 trial
  47. Imgatuzumab

    Centessa Pharmaceuticals plc

    Cutaneous Squamous Cell Carcinoma

    phase 2 small molecule terminated

    1 trial
  48. Immune Globulin Infusion (Human), 10% Solution

    Takeda

    Hematologic Malignancies

    phase 2 mab active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.