Friday, July 10, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. 90 grams of Crystalline Lactulose

    CUMBERLAND PHARMACEUTICALS INC

    Colonoscopy Preparation

    phase 2 small molecule completed

    1 trial
  2. 91-day Levonorgestrel Oral Contraceptive

    Teva Pharma GmbH

    Bone Mineral Density

    phase 2 small molecule completed

    1 trial
  3. 91-day Levonorgestrel Oral Contraceptive

    Teva Pharma GmbH

    Migraine

    phase 2 small molecule completed

    1 trial
  4. 91-day Levonorgestrel Oral Contraceptive

    Teva Pharma GmbH

    Hemostasis

    phase 2 small molecule completed

    1 trial
  5. 91396

    Bayer HealthCare AG

    Magnetic Resonance Angiography

    phase 2 small molecule completed

    1 trial
  6. 95475939ADM2001

    Janssen-Cilag International N.V.

    Moderate to Severe Atopic Dermatitis

    phase 2 small molecule active

    1 trial
  7. 9785-CL-0123

    Astellas Pharma GmbH

    Prostate Cancer

    phase 2 small molecule active

    1 trial
  8. 9941

    CNS Pharmaceuticals

    Menopause

    phase 2 small molecule terminated

    1 trial
  9. A Clinical Trial for Patients with Advanced Cancers

    Corbus Pharmaceuticals Holdings

    Advanced Solid tumour

    phase 2 other active

    1 trial
  10. A Clinical study of MK-4716 in people with certain solid tumors (MK-4716-001)

    Merck Sharp and Dohme

    Cancer – Solid Tumors : 1L NSCLC and all other advanced or metastatic solid tumors with KRAS alterations (KRAS mutation or KRAS amplification)

    phase 2 other active

    1 trial
  11. A Master Ganoderma Detox Tea

    Hong Kong Baptist University

    Eczema

    phase 2 other active

    1 trial
  12. A phase 2 trial assessing Ifenprodil as a ReM... for Multiple sclerosis

    Pari Pharma GmbH

    Multiple sclerosis

    phase 2 other active

    1 trial
  13. A study of niraparib in combination with abem... for Ovarian cancer

    Fondazione Telethon ETS

    Ovarian cancer

    phase 2 other active

    1 trial
  14. A-101

    Aclaris Therapeutics

    Seborrheic Keratosis

    phase 2 small molecule completed

    2 trials
  15. A-101 25%

    Aclaris Therapeutics

    Seborrheic Keratosis (SK)

    phase 2 small molecule completed

    1 trial
  16. A-101 Solution 40

    Aclaris Therapeutics

    Common Warts

    phase 2 small molecule completed

    1 trial
  17. A-101 Topical Solution

    Aclaris Therapeutics

    Common Wart

    phase 2 small molecule completed

    2 trials
  18. A-101 Topical Solution 40%

    Aclaris Therapeutics

    Dermatosis Papulosa Nigra

    phase 2 small molecule completed

    1 trial
  19. A-101 Vehicle

    Aclaris Therapeutics

    Seborrheic Keratosis

    phase 2 small molecule completed

    1 trial
  20. A-623

    Santhera Pharmaceuticals (Deutschland) GmbH

    Systemic Lupus Erythematosus

    phase 2 small molecule completed

    1 trial
  21. A.1 Lucinactant

    WINDTREE THERAPEUTICS INC /DE/

    Acute Respiratory Distress Syndrome

    phase 2 small molecule terminated

    1 trial
  22. A006

    Amphastar France Pharmaceuticals

    Asthma

    phase 2 small molecule completed

    1 trial
  23. A006 DPI

    Amphastar France Pharmaceuticals

    Asthma

    phase 2 small molecule completed

    2 trials
  24. A5481092

    Pfizer Australia Pty Ltd

    recurrent/refractory Ewing sarcoma, recurrent or refractory neuroblastoma

    phase 2 small molecule active

    1 trial
  25. AAV2-hAADC

    PTC THERAPEUTICS, INC.

    Aromatic Amino Acid Decarboxylase Deficiency

    phase 2 small molecule completed

    1 trial
  26. AB-101

    Artiva Biotherapeutics

    Non Hodgkin Lymphoma

    phase 2 small molecule completed

    1 trial
  27. AB-101-05

    Artiva Biotherapeutics

    Systemic Sclerosis (SSc), Rheumatoid Arthritis (RA), Idiopathic Inflammatory Myopathies (IIMs), Sjögren’s Disease (SjD)

    phase 2 small molecule active

    1 trial
  28. AB-201

    Artiva Biotherapeutics

    Breast Cancer

    phase 2 small molecule terminated

    1 trial
  29. AB-729

    Arbutus Biopharma Corp

    Chronic Hepatitis b

    phase 2 small molecule completed

    1 trial
  30. AB-729-203

    Arbutus Biopharma Corp

    Chronic HBV Infection

    phase 2 small molecule active

    1 trial
  31. AB18001

    AB Science

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  32. AB20006

    AB Science

    Mast cell activation syndrome

    phase 2 small molecule active

    1 trial
  33. AB680

    Arcus Biosciences

    Metastatic Colorectal Cancer

    phase 2 small molecule completed

    1 trial
  34. ABBV-066, Lutikizumab

    AbbVie Deutschland GmbH & Co. KG

    Psoriatic Arthritis

    phase 2 small molecule active

    1 trial
  35. ABBV-154

    AbbVie

    Crohn's Disease

    phase 2 small molecule terminated

    1 trial
  36. ABBV-552

    AbbVie

    Alzheimer's Disease (AD)

    phase 2 small molecule completed

    1 trial
  37. ABC2

    Sana Biotechnology

    Breast Cancer

    phase 2 small molecule active

    1 trial
  38. ABC294640

    Apogee Therapeutics

    Diffuse Large B Cell Lymphoma

    phase 2 small molecule terminated

    1 trial
  39. ABC294640

    Apogee Therapeutics

    Carcinoma, Hepatocellular

    phase 2 small molecule terminated

    1 trial
  40. ABC294640

    RedHill Biopharma

    Cholangiocarcinoma

    phase 2 small molecule completed

    1 trial
  41. ABCSG 45

    Shanghai Reinovax Biologics Co.,LTD

    Early invasive triple negative breast cancer with positive HRD status (acc. to Myriad mychoice© test)

    phase 2 small molecule active

    1 trial
  42. ABCSG 63

    Shanghai Reinovax Biologics Co.,LTD

    endocrine-responsive HER2-negative early breast cancer

    phase 2 small molecule active

    1 trial
  43. ABEMACICLIB , RO7197597

    Fondazione Telethon ETS

    ER-positive, HER2-negative Early breast cancer

    phase 2 small molecule active

    1 trial
  44. ABI-H0731

    ASSEMBLY BIOSCIENCES, INC.

    Chronic Hepatitis B

    phase 2 small molecule terminated

    6 trials
  45. ABO-102

    ABEONA THERAPEUTICS INC.

    MPS IIIA

    phase 2 small molecule terminated

    1 trial
  46. ABP-2019

    The George Institute

    locally advanced (stage III) and not suitable for curative treatment, or metastatic (stage IV) ALK+ NSCLC, ALK+ NSCLC

    phase 2 small molecule active

    1 trial
  47. ABP-450

    AEON Biopharma

    Migraine

    phase 2 small molecule terminated

    2 trials
  48. ABP-450

    AEON Biopharma

    Cervical Dystonia

    phase 2 small molecule completed

    2 trials

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.