Saturday, July 11, 2026
🇺🇸 FDA

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 63 of 151

  1. Guanfacine

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 small molecule completed

    1 trial

  2. Guanfacine

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Related Disorders

    phase 2 small molecule completed

    1 trial

  3. Guselkumab

    Janssen Cilag International NV

    Colitis, Ulcerative

    phase 2 mab active

    1 trial

  4. H5N1 antigen combined with MF59 adjuvant

    Seqirus (Australia) Pty Ltd

    Influenza, Human

    phase 2 mab completed

    1 trial

  5. HAIC + Tislelizumab +lenvatinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma (HCC)

    phase 2 other active

    1 trial

  6. HB-adMSC

    United Therapeutics Europe Ltd

    COVID-19

    phase 2 mab terminated

    1 trial

  7. HB0043

    The First People's Hospital of Lianyungang

    Acne Vulgaris

    phase 2 small molecule active

    1 trial

  8. HBI-3000

    International Peace Maternity and Child Health Hospital

    Atrial Fibrillation

    phase 2 small molecule active

    1 trial

  9. HCD122

    Novartis Pharmaceuticals

    Non-Hodgkin's Lymphoma

    phase 2 small molecule completed

    1 trial

  10. HCQ01

    Sana Biotechnology

    2019 Novel Coronavirus

    phase 2 small molecule active

    2 trials

  11. HDP-101

    Lacuna Pharma Pty Ltd

    Relapsed or refractory Multiple Myeloma (r/r MM)

    phase 2 small molecule active

    1 trial

  12. HEART to HAART

    BRIGHT MINDS BIOSCIENCES INC.

    HIV

    phase 2 other completed

    1 trial

  13. HEC110114 tablet

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Chronic Hepatitis C

    phase 2 small molecule completed

    2 trials

  14. HEC121120 tablets

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Hepatitis B, Chronic

    phase 2 small molecule terminated

    1 trial

  15. HEC169096

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Advanced Solid Tumor

    phase 2 small molecule active

    1 trial

  16. HEC585

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Idiopathic Pulmonary Fibrosis

    phase 2 small molecule active

    5 trials

  17. HEC585 dose A

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Progressive Fibrosing Interstitial Lung Disease (PF-ILD) / Progressive Pulmonary Fibrosis (PPF)

    phase 2 small molecule active

    1 trial

  18. HEC96719

    Sunshine Guojian Pharmaceutical (Shanghai) Co.,

    Non-Alcoholic Steatohepatitis

    phase 2 small molecule completed

    1 trial

  19. HEM-iSMART - Sub B

    AXIM BIOTECHNOLOGIES, INC.

    Acute Lymphoblastic Leukemia, in Relapse Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

    phase 2 small molecule active

    1 trial

  20. HEM-iSMART sub C

    AXIM BIOTECHNOLOGIES, INC.

    Acute Lymphoblastic Leukemia, in Relapse Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

    phase 2 small molecule active

    1 trial

  21. HER3-DXd

    Daiichi Sankyo

    Advanced Solid Tumor

    phase 2 small molecule active

    1 trial

  22. HGT-1110

    Takeda

    Metachromatic Leukodystrophy (MLD)

    phase 2 mab completed

    1 trial

  23. HGT-1111

    Takeda

    Late Infantile Metachromatic Leukodystrophy

    phase 2 small molecule terminated

    1 trial

  24. HGT-1410

    Takeda

    Sanfilippo Syndrome

    phase 2 small molecule terminated

    1 trial

  25. HH-003(20mg/kg)

    Huahui Health

    Chronic Hepatitis Delta Virus Infection

    phase 2 mab completed

    1 trial

  26. HIPER-RESET

    The George Institute

    chronic kidney disease, Hypersensitized patients

    phase 2 other active

    1 trial

  27. HKI-272

    PUMA BIOTECHNOLOGY, INC.

    Breast Cancer

    phase 2 small molecule completed

    1 trial

  28. HKI-272

    PUMA BIOTECHNOLOGY, INC.

    Carcinoma, Non-Small-Cell Lung

    phase 2 small molecule completed

    1 trial

  29. HKI-272

    PUMA BIOTECHNOLOGY, INC.

    Advanced Breast Cancer

    phase 2 small molecule completed

    2 trials

  30. HLX07+carboplatin+pemetrexed

    Shanghai Henlius Biotech

    HLX07, nsqNSCLC, High EGFR Expression

    phase 2 small molecule active

    1 trial

  31. HM-GCG-201

    Alphapharm Pty Ltd

    Congenital Hyperinsulinism (CHI)

    phase 2 other active

    1 trial

  32. HMB-001

    Hemab Therapeutics Holdings

    Glanzmann Thrombasthenia

    phase 2 small molecule active

    1 trial

  33. HMB-001

    Hemab Therapeutics Holdings

    Glanzmann Thrombasthenia

    phase 2 small molecule active

    1 trial

  34. HMB-002 (Part A)

    Hemab Therapeutics Holdings

    Von Willebrand Disease (VWD)

    phase 2 small molecule active

    1 trial

  35. HO155

    Wuhan Createrna Science and Technology Co., Ltd

    Acute myeloid leukemia, Myelodysplastic syndrome

    phase 2 small molecule active

    1 trial

  36. HO159

    Wuhan Createrna Science and Technology Co., Ltd

    Patients with relapsed CLL, Chronic lymphocytic leukemia

    phase 2 small molecule active

    1 trial

  37. HO161

    Disc Medicine

    relapsed/refractory Non-Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial

  38. HP184

    Sanofi Pasteur

    Spinal Cord Injury

    phase 2 small molecule completed

    1 trial

  39. HPV DNA Plasmids Therapeutic Vaccine VGX-3100

    INOVIO PHARMACEUTICALS, INC.

    Anal Intraepithelial Neoplasia

    phase 2 mab completed

    1 trial

  40. HRS-4642+AG+Nimotuzumab

    Zhejiang University

    Borderline Resectable Pancreatic Adenocarcinoma

    phase 2 small molecule active

    1 trial

  41. HRS-6213

    Jian Li

    Patients With Solid Tumors

    phase 2 small molecule active

    1 trial

  42. HRS-7058

    Shandong Suncadia Medicine Co.,

    Pancreatic Cancer

    phase 2 small molecule active

    1 trial

  43. HS_SW01 cells injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Primary Ovarian Insufficiency (Poi)

    phase 2 small molecule active

    1 trial

  44. HS_SW01 cells injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Ankylosing Spondylitis

    phase 2 small molecule active

    1 trial

  45. HT-001 2% Topical Gel

    Hoth Therapeutics

    Acneiform Eruption Due to Chemical

    phase 2 small molecule active

    1 trial

  46. HT-100

    Processa Pharmaceuticals

    Duchenne Muscular Dystrophy

    phase 2 small molecule terminated

    2 trials

  47. HTNV/PUUV DNA vaccine

    United Therapeutics Europe Ltd

    Hemorrhagic Fever With Renal Syndrome

    phase 2 mab completed

    1 trial

  48. HTX-011A

    Heron Therapeutics

    Postoperative Pain

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

Drug approvals, clinical trials, M&A, event intelligence, and company updates — weekly.

Customize topics & region
Topics
Region

No spam. Unsubscribe anytime. See our privacy policy.