Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Fibromun, Temozolomide SUN 100 mg hard capsules

    Philogen S.p.A.

    Glioblastoma

    phase 2 small molecule active

    1 trial
  2. Ficerafusp alfa

    Bicara Therapeutics

    Squamous Cell Carcinoma of Head and Neck (SCCHN)

    phase 2 small molecule active

    1 trial
  3. Ficerafusp alfa

    Bicara Therapeutics

    Head and Neck Squamous Cell Carcinoma (HNSCC)

    phase 2 small molecule active

    1 trial
  4. Filgotinib

    Lakefront Biotherapeutics NV

    Fistulizing Crohn's Disease

    phase 2 small molecule completed

    1 trial
  5. Filgotinib

    Lakefront Biotherapeutics NV

    Small Bowel Crohn's Disease

    phase 2 small molecule completed

    1 trial
  6. Filgotinib

    Lakefront Biotherapeutics NV

    Noninfectious Uveitis

    phase 2 small molecule terminated

    1 trial
  7. Filgotinib

    Lakefront Biotherapeutics NV

    Inflammatory Bowel Disease

    phase 2 small molecule terminated

    1 trial
  8. Film-coated placebo to match estetrol monohydrate (E4) 20mg tablet

    Estetra SPRL

    postmenopausal women with vasomotor menopausal symptoms

    phase 2 small molecule active

    1 trial
  9. Fipaxalparant

    Elan Pharma International

    Diffuse Cutaneous Systemic Sclerosis

    phase 2 small molecule active

    1 trial
  10. First-line Cohort

    The First People's Hospital of Lianyungang

    Hepatocellular Carcinoma (HCC)

    phase 2 small molecule active

    1 trial
  11. FirstHCMU-JBi-PARTOM

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Metastatic Castration-resistant Prostate Cancer

    phase 2 small molecule active

    1 trial
  12. Fisetin

    United Therapeutics Europe Ltd

    Femoroacetabular Impingement

    phase 2 small molecule active

    1 trial
  13. Fixed dose combination Ciprofloxacin/Celecoxib

    NeuroSense Therapeutics

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule completed

    1 trial
  14. Flortaucipir, Placebo to match LY3372689

    Eli Lilly Co.

    Alzheimer Disease

    phase 2 small molecule active

    1 trial
  15. Fluciclovine F18

    Telix Innovations

    Prostate Adenocarcinoma

    phase 2 small molecule active

    1 trial
  16. Fludarabina Accord /ml concentrado para soluc...

    The George Institute

    Refractary or relapse non-Hodgkin T CD30+ lymphoma., Refractary or relapse Hodgkin T CD30+ lymphoma

    phase 2 small molecule active

    1 trial
  17. Fludarabine

    Jazz Pharmaceuticals Ireland Limited

    Hematologic Malignancy

    phase 2 small molecule terminated

    1 trial
  18. Fludarabine

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia, Adult

    phase 2 small molecule terminated

    1 trial
  19. Fludarabine (FLU)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Aplastic Anemia Idiopathic

    phase 2 small molecule active

    1 trial
  20. Fludrocortisone 100 mcg daily

    Chinese University of Hong Kong

    Sepsis

    phase 2 small molecule active

    1 trial
  21. Flumazenil

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 small molecule completed

    1 trial
  22. Fluocinolone Acetonide

    ANI PHARMACEUTICALS INC

    Macular Edema

    phase 2 small molecule terminated

    1 trial
  23. Fluocinolone Acetonide

    ANI PHARMACEUTICALS INC

    Age-Related Macular Degeneration

    phase 2 small molecule terminated

    1 trial
  24. Fluorodopa F 18

    BRIGHT MINDS BIOSCIENCES INC.

    Malignant Brain Neoplasm

    phase 2 small molecule active

    1 trial
  25. Fluorouracil

    Arcus Biosciences

    Borderline Resectable Pancreatic Adenocarcinoma

    phase 2 small molecule active

    1 trial
  26. Fluorouracil

    United Therapeutics Europe Ltd

    Metastatic Biliary Tract Carcinoma

    phase 2 small molecule active

    1 trial
  27. Fluorouracil

    United Therapeutics Europe Ltd

    Clinical Stage II Esophageal Adenocarcinoma AJCC v8

    phase 2 small molecule active

    1 trial
  28. Fluorouracile AHCL /ml for colorectal cancer

    Fondazione Telethon ETS

    colorectal cancer

    phase 2 small molecule active

    1 trial
  29. Fluoxetine

    The First People's Hospital of Lianyungang

    Depression

    phase 2 small molecule active

    1 trial
  30. Fluoxetine

    BRIGHT MINDS BIOSCIENCES INC.

    Depressive Disorder, Major

    phase 2 small molecule completed

    1 trial
  31. Fluoxetine (drug)

    The First People's Hospital of Lianyungang

    Hepatobiliary Malignancy

    phase 2 small molecule active

    1 trial
  32. Flupenthixol

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial
  33. Flupenthixol

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 small molecule completed

    1 trial
  34. Fluticasone Furoate

    GlaxoSmithKline

    Asthma

    phase 2 small molecule completed

    1 trial
  35. Fluticasone furoate (FF) (100 mcg)

    GlaxoSmithKline

    Asthma

    phase 2 small molecule completed

    1 trial
  36. Fluticasone propionate

    GlaxoSmithKline

    Asthma

    phase 2 small molecule completed

    1 trial
  37. Folfox plus Bevacizumab and reolysin

    ONCOLYTICS BIOTECH INC

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial
  38. Fomivirsen sodium

    IONIS PHARMACEUTICALS INC

    Cytomegalovirus Retinitis

    phase 2 small molecule completed

    4 trials
  39. Forodesine 200 mg

    Biocryst

    Cutaneous T-cell Lymphoma (CTCL),

    phase 2 small molecule completed

    1 trial
  40. Forxiga 10 mg film-coated tablets

    Fondazione Telethon ETS

    Chemotherapy-induced cardiotoxicity in breast cancer

    phase 2 small molecule active

    1 trial
  41. Fostamatinib

    AstraZeneca

    Rheumatoid Arthritis

    phase 2 small molecule terminated

    1 trial
  42. Fostamatinib

    RIGEL PHARMACEUTICALS INC

    Myelofibrosis

    phase 2 small molecule terminated

    1 trial
  43. Fostamatinib

    RIGEL PHARMACEUTICALS INC

    Hidradenitis Suppurativa

    phase 2 small molecule completed

    1 trial
  44. Fostamatinib 150 mg

    RIGEL PHARMACEUTICALS INC

    IGA Nephropathy

    phase 2 small molecule completed

    1 trial
  45. Fostamatinib 150 mg bid

    RIGEL PHARMACEUTICALS INC

    Warm Antibody Autoimmune Hemolytic Anemia

    phase 2 small molecule completed

    1 trial
  46. Fostamatinib Disodium

    RIGEL PHARMACEUTICALS INC

    T Cell Lymphoma

    phase 2 small molecule completed

    1 trial
  47. Fostamatinib Disodium (R935788)

    RIGEL PHARMACEUTICALS INC

    Systemic Lupus Erythematosus

    phase 2 small molecule terminated

    1 trial
  48. Fostamatinib Disodium / R935788

    RIGEL PHARMACEUTICALS INC

    Purpura, Thrombocytopenic, Idiopathic

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.