Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 53 of 151
  1. Eltrombopag

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Thrombocytopenia Purpura

    phase 2 small molecule completed

    1 trial
  2. Embrace-III Hi-Risk

    Disc Medicine

    high risk or poor response after chemoradiation and brachytherapy for locally advanced cervix cancer

    phase 2 small molecule active

    1 trial
  3. EmpowHER 208

    Jazz Pharmaceuticals Ireland Limited

    HER2-positive breast cancer

    phase 2 small molecule active

    1 trial
  4. Emrusolmin

    Lacuna Pharma Pty Ltd

    Multiple System Atrophy

    phase 2 small molecule active

    1 trial
  5. EnEPC-CLI-01

    Biogen

    Peripherial arterial disease (PAD) & Chronic-Limb Threatening Ischemia (CLTI) patients who have not responded to standard pharmacological treatment or control of risk factors, and/or had a revascularisation with continued presence of smaller vessel (microvasculature) disease, and do not have the option of a revascularization treatment.

    phase 2 small molecule active

    1 trial
  6. Enasidenib

    Agios Netherlands B.V.

    Hematologic Neoplasms

    phase 2 small molecule completed

    1 trial
  7. Enasidenib Mesylate

    Jazz Pharmaceuticals Ireland Limited

    Recurrent Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  8. Encapsulated Rapamycin (eRapa)

    Biodexa Pharmaceuticals Plc

    Familial Adenomatous Polyposis

    phase 2 small molecule active

    1 trial
  9. Encochleated Amphotericin B

    Matinas BioPharma Holdings

    Cryptococcal Infections

    phase 2 small molecule terminated

    1 trial
  10. Encorafenib + Binimetinib

    Regeneron UK Limited

    Melanoma BRAF V600E/K Mutated

    phase 2 small molecule active

    1 trial
  11. Endostar

    The First People's Hospital of Lianyungang

    Brain Metastases

    phase 2 small molecule active

    1 trial
  12. Endostar

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Nasopharyngeal Neoplasms

    phase 2 small molecule active

    2 trials
  13. Endostar

    The First People's Hospital of Lianyungang

    Esophageal Cancer

    phase 2 small molecule active

    1 trial
  14. Endostatins

    The First People's Hospital of Lianyungang

    Nasopharyngeal Carcinoma

    phase 2 small molecule active

    1 trial
  15. Enekinragene Inzadenovec (PCRX-201)

    Pacira Ireland Limited

    Osteoarthritis (OA) of the Knee

    phase 2 mab active

    1 trial
  16. Enema transplant of fecal microbiota 25g/100mL

    Pari Pharma GmbH

    Austistic spectrum disorder

    phase 2 small molecule active

    1 trial
  17. Enfortumab vedotin

    United Therapeutics Europe Ltd

    Metastatic Urothelial Carcinoma

    phase 2 small molecule active

    1 trial
  18. Engineered Mitochondrial Vaccine (IMP3-Mito)

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Head and Neck Squamous Cell Carcinoma

    phase 2 mab active

    1 trial
  19. Enoxaparin

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Pregnancy Related

    phase 2 small molecule active

    1 trial
  20. Enpatoran Placebo, Enpatoran

    Merck Sharp and Dohme

    Systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE)

    phase 2 small molecule active

    1 trial
  21. Enpatoran low dose

    Serono Europe Limited

    Systemic Lupus Erythematosus

    phase 2 small molecule completed

    1 trial
  22. Ensartinib

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  23. Ensartinib

    The First People's Hospital of Lianyungang

    Solid Tumors

    phase 2 small molecule active

    1 trial
  24. Ensartinib group

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    NSCLC

    phase 2 small molecule active

    1 trial
  25. Enteric coated sevelamer

    Sanofi Pasteur

    Hypercholesterolemia

    phase 2 small molecule completed

    1 trial
  26. Entinostat

    Syndax Pharmaceuticals

    Non Small Cell Lung Cancer

    phase 2 small molecule terminated

    2 trials
  27. Entinostat

    Syndax Pharmaceuticals

    Metastatic Cholangiocarcinoma

    phase 2 small molecule completed

    1 trial
  28. Entinostat

    KYOWA KIRIN AUSTRALIA PTY LTD

    Advanced or Recurrent Breast Cancer

    phase 2 small molecule completed

    1 trial
  29. Entinostat

    Syndax Pharmaceuticals

    Melanoma

    phase 2 small molecule completed

    1 trial
  30. Entinostat

    Syndax Pharmaceuticals

    Lymphoma

    phase 2 small molecule active

    1 trial
  31. Entinostat

    Syndax Pharmaceuticals

    Renal Cell Carcinoma

    phase 2 small molecule active

    2 trials
  32. Entinostat

    Syndax Pharmaceuticals

    ER+ Breast Cancer

    phase 2 small molecule completed

    1 trial
  33. Entinostat

    Syndax Pharmaceuticals

    Hodgkin's Lymphoma

    phase 2 small molecule terminated

    1 trial
  34. Entinostat

    Syndax Pharmaceuticals

    Non-Small-Cell Lung Carcinoma

    phase 2 small molecule completed

    1 trial
  35. Entrectinib

    Hoffmann-La Roche

    Solid Tumors

    phase 2 small molecule active

    1 trial
  36. Entrectinib

    Hoffmann-La Roche

    Breast Cancer

    phase 2 small molecule active

    1 trial
  37. Entyvio 300 mg powder for concentrate for solution for infusion

    Takeda

    Ulcerative Colitis or Crohn's Disease

    phase 2 small molecule active

    1 trial
  38. Envafolimab

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 2 small molecule active

    1 trial
  39. Envafolimab

    The First People's Hospital of Lianyungang

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    1 trial
  40. Envafolimab Injection

    The First People's Hospital of Lianyungang

    Gastrointestinal Neoplasms

    phase 2 small molecule active

    1 trial
  41. Enzalutamide

    BRIGHT MINDS BIOSCIENCES INC.

    Prostate Cancer Metastatic

    phase 2 small molecule completed

    1 trial
  42. Enzalutamide

    CORCEPT THERAPEUTICS INC

    Metastatic Breast Cancer

    phase 2 small molecule active

    1 trial
  43. Enzalutamide 40mg

    United Therapeutics Europe Ltd

    Metastatic Castration-Resistant Prostate Cancer (mCRPC)

    phase 2 small molecule active

    1 trial
  44. Epcoritamab

    United Therapeutics Europe Ltd

    Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

    phase 2 mab active

    1 trial
  45. Epcoritamab

    ADC Therapeutics SA

    Large B-cell Lymphoma

    phase 2 small molecule active

    1 trial
  46. Epcoritamab for DIFFUSE LARGE B CELL LYMPHOMA

    Genmab A/S

    DIFFUSE LARGE B CELL LYMPHOMA

    phase 2 small molecule active

    1 trial
  47. Epetraborole

    AN2 Therapeutics

    Mycobacterium Abscessus Infection

    phase 2 small molecule active

    1 trial
  48. Epidyolex 100 mg/ml oral solution

    Pari Pharma GmbH

    Children and adolescents with severe neurodevelopmental disorders

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.