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Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 52 of 151

  1. EPI-589

    PTC THERAPEUTICS, INC.

    Amyotrophic Lateral Sclerosis

    phase 2 small molecule completed

    1 trial

  2. EPI-7386, Xtandi - 40 mg soft capsules

    Lacuna Pharma Pty Ltd

    Metastatic castration-resistant prostate cancer

    phase 2 small molecule active

    1 trial

  3. EPI-743

    PTC THERAPEUTICS, INC.

    Leigh Syndrome

    phase 2 small molecule completed

    1 trial

  4. EPI-U02

    Ars Pharmaceuticals Irl Limited

    Chronic Spontaneous Urticaria (CSU)

    phase 2 small molecule active

    1 trial

  5. EPINEPHRINE , Briquilimab

    Jasper Therapeutics

    Chronic Inducible Urticaria

    phase 2 small molecule active

    1 trial

  6. EPLERENONE

    The George Institute

    Heart failure with reduced ejection fraction in combination with severe chronic kidney disease

    phase 2 small molecule active

    1 trial

  7. ER004

    Pierre Fabre Medicament

    X-linked hypohidrotic ectodermal dysplasia (XLHED)

    phase 2 small molecule active

    1 trial

  8. ESR-17-13082

    Disc Medicine

    Locally advanced rectal cancer

    phase 2 small molecule active

    1 trial

  9. ESR-21-21284

    Disc Medicine

    Sjogren's disease

    phase 2 small molecule active

    1 trial

  10. ESTEVE-SANF-201

    Esteve Pharmaceuticals

    Mucopolysaccharidosis type IIIA (Sanfilippo A syndrome)

    phase 2 other active

    1 trial

  11. ET-20-049

    Lacuna Pharma Pty Ltd

    Patiens with locally advanced/metastatic endometrial carcinoma or cervix carcinoma progressing/relapsing after at least one prior systemic chemotherapy.

    phase 2 small molecule active

    1 trial

  12. ETC-1002

    Esperion Therapeutics

    Dyslipidemia

    phase 2 small molecule completed

    1 trial

  13. ETC-1002

    Esperion Therapeutics

    Hyperlipidemia

    phase 2 small molecule completed

    2 trials

  14. ETNA

    The George Institute

    Relapsed/refractory neuroblastoma and other solid tumours

    phase 2 small molecule active

    1 trial

  15. ETOP 14-18 CHESS

    Partner Therapeutics Limited

    NSCLC, synchronous oligo-metastatic

    phase 2 small molecule active

    1 trial

  16. ETOP 23-22 RAISE

    Partner Therapeutics Limited

    Extensive-disease small cell lung cancer and high SLFN11-expression

    phase 2 small molecule active

    1 trial

  17. EUCT 2024-511805-42

    Disc Medicine

    Cardiogenic shock

    phase 2 small molecule active

    1 trial

  18. EVP-6124

    BRIGHT MINDS BIOSCIENCES INC.

    Nicotine Dependence

    phase 2 small molecule terminated

    1 trial

  19. EXAFIP2

    Pari Pharma GmbH

    IDIOPATHIC PULMONARY FIBROSIS

    phase 2 small molecule active

    1 trial

  20. EXENATIDE

    Disc Medicine

    paragangliomas

    phase 2 small molecule active

    1 trial

  21. EXENATIDE

    Disc Medicine

    Gestational diabetes

    phase 2 small molecule active

    1 trial

  22. EXENATIDE , VERAPAMIL

    Disc Medicine

    type 1 diabetes mellitus

    phase 2 small molecule active

    1 trial

  23. EYP001-210

    Lacuna Pharma Pty Ltd

    Impaired renal function and suspected MASH

    phase 2 small molecule active

    1 trial

  24. EYU688

    Novartis Pharmaceuticals

    Dengue

    phase 2 small molecule active

    1 trial

  25. Eat Well Live Well Nutrition Program

    Grace Therapeutics

    Diabetes or Diabetes Prevention

    phase 2 other completed

    1 trial

  26. EcoNail™ (econazole 5%/SEPA® 18% nail lacquer)

    ABEONA THERAPEUTICS INC.

    Onychomycosis

    phase 2 small molecule completed

    1 trial

  27. Eculizumab

    Biocryst

    Paroxysmal Nocturnal Hemoglobinuria (PNH)

    phase 2 small molecule terminated

    1 trial

  28. Eculizumab

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Kidney Transplantation

    phase 2 small molecule active

    1 trial

  29. Edaravone Dexborneol

    The First People's Hospital of Lianyungang

    Stroke, Ischemic

    phase 2 small molecule active

    1 trial

  30. Efavaleukin alfa

    Amgen

    Ulcerative Colitis

    phase 2 small molecule terminated

    1 trial

  31. Efbemalenograstim alfa Injection

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Primary/Secondary Prevention

    phase 2 small molecule active

    1 trial

  32. Efgartigimod, ARGX-113

    argenx

    Chronic Inflammatory Demyelinating Polyneuropathy

    phase 2 small molecule active

    1 trial

  33. Efinopegdutide

    Merck KGaA, Darmstadt, Germany

    Non-alcoholic Fatty Liver Disease

    phase 2 small molecule completed

    1 trial

  34. Efinopegdutide 20 mg/mL

    Merck KGaA, Darmstadt, Germany

    Nonalcoholic Fatty Liver Disease

    phase 2 small molecule completed

    1 trial

  35. Ejiao compound

    The First People's Hospital of Lianyungang

    Postpartum Anemia

    phase 2 small molecule active

    1 trial

  36. Elacestrant

    Context Therapeutics

    Breast Cancer

    phase 2 small molecule terminated

    2 trials

  37. Eladocagene Exuparvovec

    PTC THERAPEUTICS, INC.

    AADC Deficiency

    phase 2 gene therapy active

    1 trial

  38. ElechtraPlatinum

    Istituto Gentili S.r.l.

    relapsing vulvar carcinoma already subjected to multiple treatments

    phase 2 small molecule active

    1 trial

  39. Elironrasib

    Revolution Medicines

    Non-Small Cell Lung Cancer (NSCLC)

    phase 2 small molecule active

    1 trial

  40. Elliptical exercise

    United Therapeutics Europe Ltd

    Adult

    phase 2 other completed

    1 trial

  41. Elotuzumab

    Atrium Therapeutics

    Multiple Myeloma

    phase 2 small molecule completed

    1 trial

  42. Elritercept

    Takeda

    Myelofibrosis

    phase 2 small molecule active

    1 trial

  43. Elritercept

    Takeda

    Myelodysplastic Syndromes

    phase 2 small molecule active

    2 trials

  44. Elsubrutinib

    AbbVie

    Systemic Lupus Erythematosus (SLE)

    phase 2 small molecule completed

    1 trial

  45. Eltrekibart

    Eli Lilly and Company

    Ulcerative Colitis

    phase 2 small molecule active

    1 trial

  46. Eltrekibart, 0.9% sodium chloride

    Eli Lilly Co.

    Moderate to Severe Hidradenitis Suppurativa

    phase 2 small molecule active

    1 trial

  47. Eltrombopag

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Chemotherapy-induced Thrombocytopenia

    phase 2 small molecule active

    1 trial

  48. Eltrombopag

    Novartis Pharmaceuticals

    Aplastic Anemia

    phase 2 small molecule completed

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.

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