Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Glioma

    phase 2 small molecule terminated

    1 trial
  2. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Glioblastoma

    phase 2 small molecule terminated

    1 trial
  3. Dordaviprone (ONC201)

    Jazz Pharmaceuticals Ireland Limited

    Endometrial Cancer Recurrent

    phase 2 small molecule terminated

    1 trial
  4. Dose 1 of BMN 331

    BioMarin Pharmaceutical Australia Pty Ltd

    Hereditary Angioedema

    phase 2 gene therapy active

    1 trial
  5. Dose A KER-012

    Keros Therapeutics

    Pulmonary Arterial Hypertension

    phase 2 mab completed

    1 trial
  6. Dose Escalation Doublet: Combination of NKTR-214 + nivolumab

    Nektar Therapeutics UK Limited

    Melanoma

    phase 2 small molecule completed

    1 trial
  7. Dose-attenuated IST and Hetrombopag

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Sever Aplastic Anaemia

    phase 2 small molecule active

    1 trial
  8. Dostarlimab

    LIXTE BIOTECHNOLOGY HOLDINGS, INC.

    Ovarian Clear Cell Carcinoma

    phase 2 small molecule active

    1 trial
  9. Dostarlimab

    Hospital Authority, Hong Kong

    Female

    phase 2 small molecule active

    1 trial
  10. Double Trouble in Recovery

    BRIGHT MINDS BIOSCIENCES INC.

    Dual Diagnosis

    phase 2 other completed

    1 trial
  11. Double-Blind 0.2mg CBP-307

    S.L

    Moderate to Severe Ulcerative Colitis

    phase 2 small molecule completed

    1 trial
  12. Double-blind investigational anti-arrhythmic

    Wyeth is now a wholly owned subsidiary of Pfizer

    Arrhythmias

    phase 2 small molecule terminated

    1 trial
  13. Doxazosin

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Dependence

    phase 2 small molecule completed

    2 trials
  14. Doxazosin 4 mg daily plus Celecoxib 200 mg every day (QD)

    Hospital Authority, Hong Kong

    Benign Prostatic Hyperplasia

    phase 2 small molecule completed

    1 trial
  15. Doxazosin 4mg/day

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking

    phase 2 small molecule completed

    1 trial
  16. Doxazosin Mesylate, Extended Release

    United Therapeutics Europe Ltd

    Stress Disorders, Post-Traumatic

    phase 2 small molecule active

    1 trial
  17. Doxazosin extended release

    BRIGHT MINDS BIOSCIENCES INC.

    Methamphetamine or Cocaine Dependence

    phase 2 small molecule completed

    1 trial
  18. Doxorubicin Hydrochloride

    Children's Hospital of Fudan University

    Childhood Renal Cell Carcinoma

    phase 2 small molecule completed

    1 trial
  19. Doxorubicin liposome

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 small molecule active

    1 trial
  20. Doxycycline

    Hospital Authority, Hong Kong

    Tuberculosis, Meningeal

    phase 2 small molecule active

    1 trial
  21. Doxycycline

    United Therapeutics Europe Ltd

    Advanced Malignant Neoplasm

    phase 2 small molecule completed

    1 trial
  22. Doxycycline EG 200 mg Tabletten

    The George Institute

    Bacterial sexually transmittable diseases (chlamydia, gonorrhea, syphilis)

    phase 2 small molecule active

    1 trial
  23. Dragon Boat Training

    The First People's Hospital of Lianyungang

    Breast Cancer

    phase 2 other active

    1 trial
  24. Dream01, IMATINIB

    Pari Pharma GmbH

    SCD severe patients

    phase 2 small molecule active

    1 trial
  25. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Dependence

    phase 2 small molecule terminated

    2 trials
  26. Dronabinol

    BRIGHT MINDS BIOSCIENCES INC.

    Cannabis Use Disorder

    phase 2 small molecule active

    1 trial
  27. Dronabinol 120mg/day

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Smoking

    phase 2 small molecule completed

    1 trial
  28. Dronabinol 30mg/day

    BRIGHT MINDS BIOSCIENCES INC.

    Marijuana Abuse

    phase 2 small molecule completed

    1 trial
  29. Dronabinol MDI

    Nektar Therapeutics UK Limited

    Migraine With Aura

    phase 2 small molecule completed

    1 trial
  30. Drug COVID19-0001-USR

    United Therapeutics Europe Ltd

    SARS-CoV-2 Infection

    phase 2 small molecule active

    1 trial
  31. Drug GC4711

    Galera Therapeutics

    SBRT

    phase 2 small molecule terminated

    1 trial
  32. Drug Omega 3

    Matinas BioPharma Holdings

    Hypertriglyceridemia

    phase 2 small molecule completed

    1 trial
  33. Drug-coated balloon angioplasty

    The First People's Hospital of Lianyungang

    Vertebral Artery Stenosis

    phase 2 other active

    1 trial
  34. Drug: B10 L-BPA Injection

    Heron Therapeutics

    Head and Neck Cancer

    phase 2 small molecule active

    1 trial
  35. Drug: GC4419

    Galera Therapeutics

    Head and Neck Cancer

    phase 2 small molecule completed

    1 trial
  36. Drug: Pembrolizumab

    Hospital Authority, Hong Kong

    Clear-cell Metastatic Renal Cell Carcinoma

    phase 2 other active

    1 trial
  37. Duobrii

    Bausch & Lomb Incorporated

    Plaque Psoriasis

    phase 2 small molecule active

    1 trial
  38. Dupilumab

    Regeneron UK Limited

    Atopic Keratoconjunctivitis

    phase 2 small molecule active

    1 trial
  39. Dupilumab

    Regeneron UK Limited

    Allergies Food Milk

    phase 2 small molecule terminated

    1 trial
  40. Dupilumab

    Coherus Oncology

    Metastatic Colorectal Cancer

    phase 2 small molecule active

    1 trial
  41. Dupilumab

    Regeneron UK Limited

    Pruritis

    phase 2 small molecule active

    1 trial
  42. Dupilumab

    Regeneron UK Limited

    Asthma, Allergic

    phase 2 small molecule active

    1 trial
  43. Dupilumab

    Regeneron UK Limited

    Prostate Cancer

    phase 2 small molecule terminated

    1 trial
  44. Dupilumab

    Regeneron UK Limited

    Eosinophilic Gastritis (EoG)

    phase 2 small molecule active

    1 trial
  45. Dupilumab

    Regeneron UK Limited

    Colitis Ulcerative

    phase 2 small molecule active

    1 trial
  46. Dupilumab

    Regeneron UK Limited

    Allergic Rhinitis

    phase 2 small molecule completed

    1 trial
  47. Dupilumab

    CATALYST PHARMACEUTICALS, INC.

    COVID-19

    phase 2 mab completed

    1 trial
  48. Dupilumab

    Regeneron UK Limited

    Peanut Allergy

    phase 2 small molecule completed

    2 trials

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.