Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 45 of 151
  1. DCC-3116-01-001

    Lacuna Pharma Pty Ltd

    Non-Small Cell Lung Cancer, Metastatic Solid Tumor, Advanced Solid Tumor

    phase 2 small molecule active

    1 trial
  2. DCCR (diazoxide choline) extended-release tablets

    SOLENO THERAPEUTICS INC

    SH2B1 Deficiency Obesity

    phase 2 small molecule active

    1 trial
  3. DCR-PHXC-204

    Lacuna Pharma Pty Ltd

    Primary Hyperoxaluria

    phase 2 other active

    1 trial
  4. DCVax-Direct

    NORTHWEST BIOTHERAPEUTICS INC

    Locally Advanced Tumor

    phase 2 mab active

    1 trial
  5. DCVax-L and T Cells

    NORTHWEST BIOTHERAPEUTICS INC

    Ovarian Cancer

    phase 2 mab terminated

    1 trial
  6. DEB-TACE+HAIC

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Hepatocellular Carcinoma Non-resectable

    phase 2 small molecule active

    1 trial
  7. DEDALO

    Fondazione Telethon ETS

    Multiple Myeloma relapsed and/or refractory

    phase 2 small molecule active

    1 trial
  8. DEFEROXAMINE , GALLIUM (68GA) CHLORIDE

    Disc Medicine

    Pulmonary aspergillosis

    phase 2 small molecule active

    1 trial
  9. DESF

    Aquestive Therapeutics

    Allergic Reaction

    phase 2 small molecule completed

    1 trial
  10. DESTINY-Breast07

    AstraZeneca AB

    HER2-positive Metastatic Breast Cancer

    phase 2 small molecule active

    1 trial
  11. DESTRESS-PC

    United Therapeutics Europe Ltd

    Posttraumatic Stress Disorder (PTSD)

    phase 2 other completed

    1 trial
  12. DEXAMETHASONE for Patients with relapsed/refracto…

    Pari Pharma GmbH

    Patients with relapsed/refractory symptomatic multiple myeloma (MM)

    phase 2 small molecule active

    1 trial
  13. DIABECELL(R)

    Otsuka Beijing Research Institute

    Type 1 Diabetes

    phase 2 other completed

    1 trial
  14. DIMETHYL FUMARATE, DIMETHYL FUMARATE

    Pari Pharma GmbH

    Macular degeneration

    phase 2 small molecule active

    1 trial
  15. DIPG

    Fondazione Telethon ETS

    Diffuse intrinsic pontine glioma

    phase 2 small molecule active

    1 trial
  16. DISC-0974

    Disc Medicine

    Myelofibrosis; Anemia

    phase 2 small molecule active

    1 trial
  17. DISC-0974

    Disc Medicine

    Inflammatory Bowel Disease (IBD)

    phase 2 small molecule active

    1 trial
  18. DISC-3405

    Disc Medicine

    Polycythemia Vera (PV)

    phase 2 small molecule active

    1 trial
  19. DM199

    DiaMedica Therapeutics

    Kidney Diseases

    phase 2 small molecule completed

    1 trial
  20. DM199

    DiaMedica Therapeutics

    Diabetes Type 2

    phase 2 small molecule completed

    1 trial
  21. DMT210 Topical Gel

    Dermata Therapeutics

    Atopic Dermatitis

    phase 2 small molecule completed

    1 trial
  22. DMT210 Topical Gel 5%

    Dermata Therapeutics

    Acne Rosacea

    phase 2 small molecule completed

    1 trial
  23. DMTs + taurine

    The First People's Hospital of Lianyungang

    Multiple Sclerosis (MS) Relapsing Remitting

    phase 2 small molecule active

    1 trial
  24. DNA vaccine

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    AIDS

    phase 2 mab completed

    1 trial
  25. DNA vaccine prime

    United Therapeutics Europe Ltd

    Malaria

    phase 2 mab completed

    1 trial
  26. DNL126

    Denali Therapeutics

    Mucopolysaccharidosis Type IIIA

    phase 2 small molecule active

    1 trial
  27. DNL593

    Denali Therapeutics

    Frontotemporal Dementia

    phase 2 small molecule active

    1 trial
  28. DNLI-E-0002

    Denali Therapeutics

    Hunter Syndrome (Mucopolysaccharidosis Type II [MPS II])

    phase 2 other active

    1 trial
  29. DNLI-H-0001

    Denali Therapeutics

    Frontotemporal Dementia (FTD)

    phase 2 small molecule active

    1 trial
  30. DNS-6288, DNS-6288

    Lacuna Pharma Pty Ltd

    Catecholaminergic Polymorphic Ventricular Tachycardia

    phase 2 small molecule active

    1 trial
  31. DNTH103

    Dianthus Therapeutics, Inc. /DE/

    Myasthenia Gravis, Generalized

    phase 2 small molecule active

    1 trial
  32. DNTH103, Matching placebo to DNTH103

    Dianthus Therapeutics, Inc. /DE/

    Multifocal Motor Neuropathy

    phase 2 small molecule active

    1 trial
  33. DNTH103-MG-201

    Dianthus Therapeutics, Inc. /DE/

    Generalized Myasthenia Gravis

    phase 2 small molecule active

    1 trial
  34. DOR/ISL

    Merck KGaA, Darmstadt, Germany

    HIV-1 Infection

    phase 2 small molecule completed

    1 trial
  35. DR-1031

    Teva Pharma GmbH

    Breakthrough Bleeding

    phase 2 small molecule completed

    1 trial
  36. DR-2001a

    Teva Pharma GmbH

    Endometriosis

    phase 2 small molecule completed

    1 trial
  37. DR-2021a

    Teva Pharma GmbH

    Amenorrhea

    phase 2 small molecule completed

    1 trial
  38. DR-3001a

    Teva Pharma GmbH

    Urinary Incontinence

    phase 2 small molecule completed

    1 trial
  39. DR220204

    Tour Hekla

    psychiatry

    phase 2 small molecule active

    1 trial
  40. DR220214

    Tour Hekla

    Pneumocystis pneumonia

    phase 2 other active

    1 trial
  41. DR230070

    Tour Hekla

    Prevention of post-traumatic stress disorder

    phase 2 small molecule active

    1 trial
  42. DR230330 – ANRS0514s

    Tour Hekla

    Healthy volunteers

    phase 2 small molecule active

    1 trial
  43. DRI17476

    Sanofi-aventis Healthcare Pty Ltd

    Type 1 diabetes mellitus

    phase 2 other active

    1 trial
  44. DRI17821

    Sanofi-aventis Healthcare Pty Ltd

    Rheumatoid arthritis

    phase 2 small molecule active

    1 trial
  45. DRI17849

    Sanofi-aventis Healthcare Pty Ltd

    Psoriasis

    phase 2 small molecule active

    1 trial
  46. DRI17963

    Sanofi-aventis Healthcare Pty Ltd

    Coeliac disease

    phase 2 small molecule active

    1 trial
  47. DRI18180

    Sanofi-aventis Healthcare Pty Ltd

    Alopecia areata

    phase 2 small molecule active

    1 trial
  48. DRI18450

    Sanofi-aventis Healthcare Pty Ltd

    Crohn’s disease

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.