Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

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  1. Cyclophosphamide

    The First People's Hospital of Lianyungang

    Acute Lymphoblastic Leukemia, Pediatric

    phase 2 small molecule active

    1 trial
  2. Cyclophosphamide

    Takeda

    B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

    phase 2 small molecule active

    1 trial
  3. Cyclophosphamide

    ADC Therapeutics SA

    Double-Expressor Lymphoma

    phase 2 small molecule active

    1 trial
  4. Cyclophosphamide

    Iovance Biotherapeutics B.V.

    Clinical Stage IV Cutaneous Melanoma AJCC v8

    phase 2 small molecule completed

    1 trial
  5. Cyclophosphamide

    Iovance Biotherapeutics B.V.

    Metastatic Bladder Urothelial Carcinoma

    phase 2 small molecule terminated

    1 trial
  6. Cyclophosphamide Doxorubicin Vincristine Lamivudine

    Taiwan Liposome Company

    Non-Hodgkin's Lymphoma

    phase 2 small molecule completed

    1 trial
  7. Cyclophosphamide+Pemetrexed+5-Fluorouracil

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Locally Advanced Thyroid Gland Carcinoma

    phase 2 small molecule active

    1 trial
  8. Cycloserine

    BRIGHT MINDS BIOSCIENCES INC.

    Opioid-Related Disorders

    phase 2 small molecule terminated

    1 trial
  9. Cyclosporine A

    The First People's Hospital of Lianyungang

    Bone Marrow Failure Disorders

    phase 2 small molecule active

    1 trial
  10. Cyproterone acetate 5

    Teva Pharma GmbH

    Prostate Cancer

    phase 2 small molecule completed

    1 trial
  11. Cyproterone acetate/ethinylestradiol (CPA/EE)

    Universal Integrated

    Polycystic Ovarian Syndrome

    phase 2 small molecule completed

    1 trial
  12. Cyramza /ml concentrate for stomach cancer stage IV with me…

    CERO THERAPEUTICS HOLDINGS, INC.

    stomach cancer stage IV with metastases

    phase 2 small molecule active

    1 trial
  13. Cytarabine

    Jazz Pharmaceuticals Ireland Limited

    Leukemia

    phase 2 small molecule terminated

    1 trial
  14. Cytarabine

    Teva Pharma GmbH

    Acute Myeloid Leukemia

    phase 2 small molecule terminated

    1 trial
  15. Cytarabine

    Kura Oncology

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  16. Cytarabine

    Hospital Authority, Hong Kong

    AML

    phase 2 small molecule active

    1 trial
  17. Cytarabine (Phase 1 only)

    Actinium Pharmaceuticals

    AML

    phase 2 small molecule completed

    1 trial
  18. Cytarabine and Idarubicin

    Jazz Pharmaceuticals Ireland Limited

    Acute Myeloid Leukemia

    phase 2 small molecule active

    1 trial
  19. Cytokine-induced killer cells

    The First People's Hospital of Lianyungang

    Melanoma

    phase 2 mab active

    1 trial
  20. Cytokine-induced killer cells

    The First People's Hospital of Lianyungang

    Ovarian Carcinoma

    phase 2 mab active

    1 trial
  21. Cytovir-ADV

    United Therapeutics Europe Ltd

    ADV Infection Post Allo-HSCT

    phase 2 mab completed

    1 trial
  22. D-Amphetamine 30mg

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine-Related Disorders

    phase 2 small molecule completed

    1 trial
  23. D-Cycloserine

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking Cessation

    phase 2 small molecule terminated

    1 trial
  24. D-Cycloserine (DCS)

    BRIGHT MINDS BIOSCIENCES INC.

    Cocaine Use Disorders

    phase 2 small molecule completed

    1 trial
  25. D-FR-10200-001

    Ipsen

    Upper limb spasticity after stroke or traumatic brain injury

    phase 2 small molecule active

    1 trial
  26. D-FR-10200-002

    Ipsen

    Treatment of Moderate to Severe Upper Facial Lines

    phase 2 small molecule active

    1 trial
  27. D-cycloserine

    BRIGHT MINDS BIOSCIENCES INC.

    Substance-Related Disorders

    phase 2 small molecule terminated

    1 trial
  28. D20-P012

    Pari Pharma GmbH

    Alzheimer Disease

    phase 2 small molecule active

    1 trial
  29. D20181321

    Pari Pharma GmbH

    recurrent primary supratentorial malignant brain tumors in children

    phase 2 small molecule active

    1 trial
  30. D22-P020

    Pari Pharma GmbH

    Anorexia nervosa

    phase 2 small molecule active

    1 trial
  31. D23-P006

    Pari Pharma GmbH

    Alzeihmer disease

    phase 2 small molecule active

    1 trial
  32. D24-P003

    Pari Pharma GmbH

    Treatment-resistant depression

    phase 2 small molecule active

    1 trial
  33. D361FC00001

    AstraZeneca AB

    Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

    phase 2 small molecule active

    1 trial
  34. D4190C00022

    AstraZeneca AB

    Hepatocellular Carcinoma

    phase 2 small molecule active

    1 trial
  35. D419EC00001

    AstraZeneca AB

    Advanced Solid Tumors

    phase 2 small molecule active

    1 trial
  36. D4880C00003

    AstraZeneca AB

    unresectable pleural or peritoneal malignant mesothelioma

    phase 2 small molecule active

    1 trial
  37. D5162C00048

    AstraZeneca AB

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  38. D516AC00003

    AstraZeneca AB

    Unresectable Non-small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  39. D5336C00001

    AstraZeneca AB

    Triple Negative Breast Cancer

    phase 2 small molecule active

    1 trial
  40. D533AC00001

    AstraZeneca AB

    Unresectable or Advanced Melanoma

    phase 2 small molecule active

    1 trial
  41. D6132C00001

    AstraZeneca AB

    First-line patients with extensive disease small-cell lung cancer (SCLC)

    phase 2 small molecule active

    1 trial
  42. D6186C00001

    AstraZeneca AB

    Advanced Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  43. D6187C00001

    AstraZeneca AB

    Non-Small Cell Lung Cancer

    phase 2 small molecule active

    1 trial
  44. D6405C00002

    AstraZeneca AB

    Chronic Kidney Disease and Albuminuria

    phase 2 small molecule active

    1 trial
  45. D6405C00002

    AstraZeneca

    Chronic Kidney Disease

    phase 2 small molecule completed

    1 trial
  46. D6830C00003

    AstraZeneca AB

    Asthma in adults who remain uncontrolled despite medium to high dose ICS plus LABA, and who are at risk of exacerbations.

    phase 2 small molecule active

    1 trial
  47. D6972C00006

    AstraZeneca AB

    Chronic kidney disease (CKD) and hypertension.

    phase 2 small molecule active

    1 trial
  48. D702KC00001

    AstraZeneca AB

    metastatic non-small cell lung cancer (NSCLC)

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.