Saturday, July 11, 2026

Intelligence · Clinical pipeline

Phase II Pipeline Programs

Proof-of-concept and dose-finding clinical programs in Phase II development.

Programs 7,238
Sponsors 1,771
Drugs 4,798

Quick answer

NovaPharmaNews tracks 7,238 phase ii pharmaceutical pipeline programs from ClinicalTrials.gov. Proof-of-concept and dose-finding clinical programs in Phase II development.

Top sponsors

Pipeline programs

Page 42 of 151
  1. Cognitive Behavioral Therapy (CBT)

    BRIGHT MINDS BIOSCIENCES INC.

    Stress Disorders, Post Traumatic

    phase 2 other completed

    1 trial
  2. Cohort A: ORMD-0801

    ORAMED PHARMACEUTICALS INC.

    T2DM (Type 2 Diabetes Mellitus)

    phase 2 small molecule completed

    1 trial
  3. Cohort A: vilobelimab

    Edesa Biotech

    Acute Respiratory Distress Syndrome (ARDS)

    phase 2 small molecule active

    2 trials
  4. Cohort B: paridiprubart

    Edesa Biotech

    Acute Respiratory Distress Syndrome (ARDS)

    phase 2 small molecule active

    1 trial
  5. Cohort C: bevacizumab

    Edesa Biotech

    Acute Respiratory Distress Syndrome (ARDS)

    phase 2 small molecule active

    1 trial
  6. Colchicine

    Ultragenyx UK Limited

    Primary Cutaneous Vasculitis

    phase 2 small molecule active

    1 trial
  7. Colchicine 0.5mg

    Xiyuan Hospital of China Academy of Chinese Medical Sciences

    Cerebral Amyloid Angiopathy

    phase 2 small molecule active

    1 trial
  8. Colchicine, 0.6 mg PO BID

    Takeda

    Atrial Fibrillation

    phase 2 small molecule completed

    1 trial
  9. Cold Stored Platelets (CSP)

    United Therapeutics Europe Ltd

    Trauma

    phase 2 mab completed

    1 trial
  10. Cold stored platelets in 100% plasma stored for 10-14 days

    United Therapeutics Europe Ltd

    Hemorrhage

    phase 2 mab active

    1 trial
  11. Colonoscopy with enhanced dye

    Cardiff Oncology

    Colorectal Cancer

    phase 2 other completed

    1 trial
  12. Combination of MK3475 with Metronomic CP

    Lxo Ireland Designated Activity Company

    Sarcoma

    phase 2 small molecule completed

    1 trial
  13. Combination of Palbociclib and aromatase inhibitor (Letrozole or Anastrozole)

    United Therapeutics Europe Ltd

    Hormonal Receptors Positive, HER2 Negative, Advanced Breast Cancer

    phase 2 small molecule active

    1 trial
  14. Combination therapy (COMB)

    The First People's Hospital of Lianyungang

    Esophageal Squamous Cell Carcinoma (ESCC)

    phase 2 small molecule active

    1 trial
  15. Combinations

    The First People's Hospital of Lianyungang

    Colorectal Cancer

    phase 2 small molecule completed

    1 trial
  16. Combined intervention

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 2 other completed

    1 trial
  17. Community Reinforcement Approach (CRA) + HIV prevention

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 other completed

    1 trial
  18. Comparator: MK0594 5 mg/day

    VYNE Therapeutics

    Alcohol Dependence

    phase 2 small molecule terminated

    1 trial
  19. Computer-based Motivational Interviewing

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Abuse

    phase 2 other completed

    1 trial
  20. Computer-delivered brief intervention (5As)

    BRIGHT MINDS BIOSCIENCES INC.

    Smoking

    phase 2 other completed

    1 trial
  21. Computerized cognitively stimulating activities

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Use Disorders

    phase 2 other completed

    1 trial
  22. Computerized tasks

    BRIGHT MINDS BIOSCIENCES INC.

    Substance Use Disorders

    phase 2 other completed

    1 trial
  23. Concord grape juice

    United Therapeutics Europe Ltd

    Gulf War Illness

    phase 2 other completed

    1 trial
  24. Contingency Management-Family Engagement (CM-FAM)

    BRIGHT MINDS BIOSCIENCES INC.

    Adolescent Substance Use

    phase 2 other completed

    1 trial
  25. Convalescent Plasma

    United Therapeutics Europe Ltd

    COVID-19

    phase 2 mab terminated

    1 trial
  26. Conventional Roux-en-Y Gastrojejunostomy

    The First People's Hospital of Lianyungang

    Gastric Cancer

    phase 2 other active

    1 trial
  27. Conventional therapy

    Chinese Academy of Sciences

    Decompensated Cirrhosis

    phase 2 mab active

    1 trial
  28. Copegus

    Hoffmann-La Roche

    Hepatitis C, Chronic

    phase 2 small molecule completed

    1 trial
  29. Coreg

    BRIGHT MINDS BIOSCIENCES INC.

    Anxiety

    phase 2 small molecule terminated

    1 trial
  30. Coriolus Versicolor

    Hospital Authority, Hong Kong

    Carcinoma

    phase 2 small molecule terminated

    1 trial
  31. CoronaVac®

    Sinovac Research and Development Co.,

    COVID-19

    phase 2 mab completed

    1 trial
  32. Coronary Artery Stenting

    Medtronic BioPharma B.V.

    Coronary Artery Disease

    phase 2 other completed

    1 trial
  33. Cotellic 20 mg film-coated tablets, Ginisortamab

    Ningbo Cancer Hospital

    Metastatic pancreatic ductal adenocarcinoma

    phase 2 small molecule active

    1 trial
  34. Cotinine fumarate

    BRIGHT MINDS BIOSCIENCES INC.

    Tobacco Use Disorder

    phase 2 small molecule completed

    2 trials
  35. Coversin

    Akari Therapeutics Plc

    Paroxysmal Nocturnal Haemoglobinuria (PNH)

    phase 2 small molecule completed

    1 trial
  36. Coversin

    Akari Therapeutics Plc

    Paroxysmal Nocturnal Hemoglobinuria (PNH)

    phase 2 small molecule completed

    1 trial
  37. Cretostimogene Grenadenorepvec

    CG Oncology

    High-Risk Non-Muscle-Invasive Bladder Cancer

    phase 2 small molecule active

    1 trial
  38. Crinecerfont

    NEUROCRINE BIOSCIENCES INC

    CAH - Congenital Adrenal Hyperplasia

    phase 2 small molecule completed

    1 trial
  39. Crofelemer Placebo Powder for Oral Solution

    Lacuna Pharma Pty Ltd

    Microvillous Inclusion Disease (MVID)

    phase 2 small molecule active

    1 trial
  40. Crystalline Lactulose

    CUMBERLAND PHARMACEUTICALS INC

    Colonoscopy

    phase 2 small molecule completed

    1 trial
  41. Curosurf for Premature infants with Respiratory Distress Syndrome (RDS)

    The George Institute

    Premature infants with Respiratory Distress Syndrome (RDS)

    phase 2 small molecule active

    1 trial
  42. Cutting balloon followed by paclitaxel coated balloon

    Hospital Authority, Hong Kong

    Dialysis Access Malfunction

    phase 2 other completed

    1 trial
  43. Cx611

    Takeda

    Bacterial Pneumonia

    phase 2 mab completed

    1 trial
  44. Cyclobenzaprine HCl

    Tonix Pharmaceuticals Holding

    Acute Stress Reaction

    phase 2 small molecule active

    1 trial
  45. Cyclophosphamide

    Iovance Biotherapeutics B.V.

    Clinical Stage IV Cutaneous Melanoma AJCC v8

    phase 2 small molecule completed

    1 trial
  46. Cyclophosphamide

    United Therapeutics Europe Ltd

    Metastatic Melanoma

    phase 2 small molecule terminated

    1 trial
  47. Cyclophosphamide

    Karyopharm Therapeutics Inc

    Myeloma Multiple

    phase 2 small molecule terminated

    1 trial
  48. Cyclophosphamide

    The First People's Hospital of Lianyungang

    Acute Lymphoblastic Leukemia, Pediatric

    phase 2 small molecule active

    1 trial

Frequently asked questions

How many Phase II pipeline programs are in the directory?

7,238 published programs match this development stage in our ClinicalTrials.gov index.

What defines this pipeline stage?

Phase and status reflect ClinicalTrials.gov registry fields at last sync. See our clinical trial phases reference for methodology.